ID K7EMP0_HUMAN Unreviewed; 117 AA.
AC K7EMP0;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Major facilitator superfamily domain containing 11 {ECO:0000313|Ensembl:ENSP00000466584.1};
DE Flags: Fragment;
GN Name=MFSD11 {ECO:0000313|Ensembl:ENSP00000466584.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000466584.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000466584.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16625196; DOI=10.1038/nature04689;
RA Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT human lineage.";
RL Nature 440:1045-1049(2006).
RN [2] {ECO:0000313|Ensembl:ENSP00000466584.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AC005837; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC027694; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7EMP0; -.
DR SMR; K7EMP0; -.
DR PeptideAtlas; K7EMP0; -.
DR Ensembl; ENST00000585584.5; ENSP00000466584.1; ENSG00000092931.12.
DR UCSC; uc060knj.1; human.
DR HGNC; HGNC:25458; MFSD11.
DR VEuPathDB; HostDB:ENSG00000092931; -.
DR GeneTree; ENSGT00390000012918; -.
DR HOGENOM; CLU_2090250_0_0_1; -.
DR ChiTaRS; MFSD11; human.
DR Proteomes; UP000005640; Chromosome 17.
DR Bgee; ENSG00000092931; Expressed in buccal mucosa cell and 168 other cell types or tissues.
DR ExpressionAtlas; K7EMP0; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR010291; Ion_channel_UNC-93.
DR PANTHER; PTHR23294; ET TRANSLATION PRODUCT-RELATED; 1.
DR PANTHER; PTHR23294:SF0; UNC93-LIKE PROTEIN MFSD11; 1.
DR Pfam; PF05978; UNC-93; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSP00000466584.1"
SQ SEQUENCE 117 AA; 13210 MW; 603E24E37AD2FE0E CRC64;
QGNCLTINSD EHSIGRNSGI FWALLQSSLF FGNLYIYFAW QGKTQISESD RRTVFIALTV
ISLVGTVLFF LIRKPDSENV LGEDESSDDQ DMEVNEHWVF YKLKACGNPA SSLPRTI
//
