ID K7ES56_HUMAN Unreviewed; 105 AA.
AC K7ES56;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Regulatory factor X2 {ECO:0000313|Ensembl:ENSP00000468561.1};
DE Flags: Fragment;
GN Name=RFX2 {ECO:0000313|Ensembl:ENSP00000468561.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000468561.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000468561.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [2] {ECO:0007829|PubMed:23186163}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=23186163;
RA Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA Mohammed S.;
RT "Toward a comprehensive characterization of a human cancer cell
RT phosphoproteome.";
RL J. Proteome Res. 12:260-271(2013).
RN [3] {ECO:0000313|Ensembl:ENSP00000468561.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC011444; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC011471; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC104538; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF456482; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF456484; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7ES56; -.
DR MassIVE; K7ES56; -.
DR MaxQB; K7ES56; -.
DR PeptideAtlas; K7ES56; -.
DR Antibodypedia; 24073; 169 antibodies from 25 providers.
DR Ensembl; ENST00000592281.5; ENSP00000468561.1; ENSG00000087903.13.
DR UCSC; uc060sgn.1; human.
DR HGNC; HGNC:9983; RFX2.
DR VEuPathDB; HostDB:ENSG00000087903; -.
DR GeneTree; ENSGT01050000244879; -.
DR OMA; QFIDMSH; -.
DR ChiTaRS; RFX2; human.
DR Proteomes; UP000005640; Chromosome 19.
DR Bgee; ENSG00000087903; Expressed in right uterine tube and 176 other cell types or tissues.
DR ExpressionAtlas; K7ES56; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR InterPro; IPR007668; RFX1_trans_act.
DR Pfam; PF04589; RFX1_trans_act; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|MaxQB:K7ES56,
KW ECO:0007829|PeptideAtlas:K7ES56};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 4..104
FT /note="RFX1 transcription activation region"
FT /evidence="ECO:0000259|Pfam:PF04589"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 105
FT /evidence="ECO:0000313|Ensembl:ENSP00000468561.1"
SQ SEQUENCE 105 AA; 11044 MW; E80A22A197B4CEB0 CRC64;
MQNSEGGADS PASVALRPSA AAPPVPASPQ RVLVQAASSN PKGAQMQPIS LPRVQQVPQQ
VQPVQHVYPA QVQYVEGGDA VYTNGAIRTA YTYNPEPQMY APSST
//
