ID K7ESA3_HUMAN Unreviewed; 125 AA.
AC K7ESA3;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Vesicle amine transport 1 {ECO:0000313|Ensembl:ENSP00000468621.1};
DE Flags: Fragment;
GN Name=VAT1 {ECO:0000313|Ensembl:ENSP00000468621.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000468621.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000468621.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16625196; DOI=10.1038/nature04689;
RA Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT human lineage.";
RL Nature 440:1045-1049(2006).
RN [2] {ECO:0007829|PubMed:21269460}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Burckstummer T.,
RA Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [3] {ECO:0007829|PubMed:25944712}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=25944712;
RA Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M., Ayoub D.,
RA Lane L., Bairoch A., Van Dorsselaer A., Carapito C.;
RT "N-terminome analysis of the human mitochondrial proteome.";
RL Proteomics 15:2519-2524(2015).
RN [4] {ECO:0000313|Ensembl:ENSP00000468621.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC055866; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC135721; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7ESA3; -.
DR SMR; K7ESA3; -.
DR MassIVE; K7ESA3; -.
DR MaxQB; K7ESA3; -.
DR PeptideAtlas; K7ESA3; -.
DR Antibodypedia; 29494; 124 antibodies from 25 providers.
DR Ensembl; ENST00000587147.1; ENSP00000468621.1; ENSG00000108828.16.
DR UCSC; uc060frc.1; human.
DR HGNC; HGNC:16919; VAT1.
DR VEuPathDB; HostDB:ENSG00000108828; -.
DR GeneTree; ENSGT00940000157579; -.
DR HOGENOM; CLU_1883493_0_0_1; -.
DR ChiTaRS; VAT1; human.
DR Proteomes; UP000005640; Chromosome 17.
DR Bgee; ENSG00000108828; Expressed in right adrenal gland cortex and 206 other cell types or tissues.
DR ExpressionAtlas; K7ESA3; baseline and differential.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR44054:SF1; SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG; 1.
DR PANTHER; PTHR44054; SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:K7ESA3,
KW ECO:0007829|MaxQB:K7ESA3};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSP00000468621.1"
SQ SEQUENCE 125 AA; 13576 MW; D22B3E09BA189A0F CRC64;
SPKGVDIVMD PLGGSDTAKG YNLLKPMGKV VTYGMANLLT GPKRNLMALA RTWWNQFSVT
ALQLLQANRA VCGFHLGYLD GEVELVSGVV ARLLALYNQG HIKPHIDSVW PFEKVNVRTL
QGGLG
//
