ID K7ETN7_PONAB Unreviewed; 508 AA.
AC K7ETN7; A0A2J8X7E3;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=F-box and WD repeat domain containing 11 {ECO:0000313|Ensembl:ENSPPYP00000023910.2};
DE SubName: Full=FBXW11 isoform 3 {ECO:0000313|EMBL:PNJ77954.1};
GN Name=FBXW11 {ECO:0000313|Ensembl:ENSPPYP00000023910.2};
GN ORFNames=CR201_G0004783 {ECO:0000313|EMBL:PNJ77954.1};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000023910.2, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000023910.2, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PNJ77954.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Susie {ECO:0000313|EMBL:PNJ77954.1};
RA Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M.,
RA Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J.,
RA Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M.,
RA Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B.,
RA Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.;
RT "High-resolution comparative analysis of great ape genomes.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPPYP00000023910.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; NDHI03003371; PNJ77954.1; -; Genomic_DNA.
DR Ensembl; ENSPPYT00000033174.2; ENSPPYP00000023910.2; ENSPPYG00000016040.3.
DR GeneTree; ENSGT00940000155898; -.
DR HOGENOM; CLU_000288_57_33_1; -.
DR Proteomes; UP000001595; Chromosome 5.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd22183; F-box_FBXW1B; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 6.10.250.1840; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR021977; Beta-TrCP_D.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR14604:SF6; F-BOX AND WD REPEAT DOMAIN-CONTAINING 11-B; 1.
DR PANTHER; PTHR14604; WD40 REPEAT PF20; 1.
DR Pfam; PF12125; Beta-TrCP_D; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM01028; Beta-TrCP_D; 1.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50181; FBOX; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 4.
DR PROSITE; PS50082; WD_REPEATS_2; 7.
DR PROSITE; PS50294; WD_REPEATS_REGION; 5.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001595};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 95..133
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT REPEAT 202..241
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 242..281
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 282..321
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 325..364
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 365..404
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 405..437
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 454..484
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 508 AA; 58422 MW; 05C691DB32A91B50 CRC64;
MEPDSVIEDK TIELMISNGT SSVIVSRKRP SEGNYQKEKD LCIKYFDQWS ESDQVEFVEH
LISRMCHYQH GHINSYLKPM LQRDFITALP EQGLDHIAEN ILSYLDARSL CAAELVCKEW
QRVISEGMLW KKLIERMVRT DPLWKGLSER RGWDQYLFKN RPTDGPPNSF YRSLYPKIIQ
DIETIESNWR CGRHNLQRIQ CRSENSKGVY CLQYDDEKII SGLRDNSIKI WDKTSLECLK
VLTGHTGSVL CLQYDERVIV TGSSDSTVRV WDVNTGEVLN TLIHHNEAVL HLRFSNGLMV
TCSKDRSIAV WDMASATDIT LRRVLVGHRA AVNVVDFDDK YIVSASGDRT IKVWSTSTCE
FVRTLNGHKR GIACLQYRDR LVVSGSSDNT IRLWDIECGA CLRVLEGHEE LVRCIRFDNK
RIVSGAYDGK IKVWDLQAAL DPRAPASTLC LRTLVEHSGR VFRLQFDEFQ IISSSHDDTI
LIWDFLNVPP SAQNETRSPS RTYTYISR
//
