ID K7EZR9_PELSI Unreviewed; 757 AA.
AC K7EZR9;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000001279.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000001279.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01166623; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7EZR9; -.
DR Ensembl; ENSPSIT00000001281.1; ENSPSIP00000001279.1; ENSPSIG00000001281.1.
DR eggNOG; KOG3594; Eukaryota.
DR GeneTree; ENSGT00940000163564; -.
DR HOGENOM; CLU_006480_3_0_1; -.
DR OMA; KEMFTID; -.
DR TreeFam; TF332299; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 6.
DR Gene3D; 2.60.40.60; Cadherins; 6.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF133; PROTOCADHERIN ALPHA-9; 1.
DR Pfam; PF00028; Cadherin; 5.
DR Pfam; PF08266; Cadherin_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 6.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 4.
DR PROSITE; PS50268; CADHERIN_2; 6.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..757
FT /note="Cadherin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003904479"
FT TRANSMEM 681..702
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..121
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 130..230
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 231..338
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 339..443
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 444..553
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 568..670
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 757 AA; 80901 MW; F2A67A02677CE66B CRC64;
QLLRWVLLQA AWAASGGQLH YSVPEEAEPG TLVGRLAQDV GLEVAELVSR RLRAVAKGGR
DCFEVNAQSG ALLVKSRLDR EELCGPSPRC ALDLEVLVDK PLRLFPVEVE IRDINDNAPA
FAVNEDFLFI SESRLPGSRF PLEGASDADI GTNSLLSYTL SPNEYFSLDV QRKNDLSKSL
VLVLKKPLDR EETPEHRLLL TATDGGKPEL TGTAQLVISV LDVNDNAPVF NQPVYEVRIL
EGTANGTLVI KLNATDSDEG VNKDVLYFFN NRVPSSVKQM FSIDRNTGEF RVNDELDFED
TNLYEIQIEA IDKGTPPMVG HCKVLVEVLD VNDHAPELAV TSLSLPVPED APPGTVVALL
SVSDRDSGDN GKVSCSIGPG LPFRLVSTFK NYHSLVVAEA LDRERVAEYE VVVRARDQGA
PPLWASRRLV VPLSDVNDNA PAFPQAVYTV FVRENNPAGA PVLSVSAWDP DLGANGRVSY
WAVERRVGER PLSSYISVHS ESGQVSALQP LDYEELQVLQ FEVSARDAGL PALCGNVSVQ
LFVLDANDNA PVVSPPGSGR GALGPELVPL SAGAGHVVGK VRAVDADSGY NAWLRYELQE
PRAAGPFRVG VYSGEISTAR ALEEADGPSR SLVIVVRDHG EPALSATATV SLSLSERAQA
VAWESGPPRA GSAGPAGAMN VSLMIAICSV SGLFVLVIVL YVGLRCPGAP EVTCGPGKGP
GAGASASEAG SWSYSQRQSR LVCVGEGTVR SDLMVFS
//
