ID K7F2L7_PELSI Unreviewed; 322 AA.
AC K7F2L7;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=CD200 receptor 1 {ECO:0000313|Ensembl:ENSPSIP00000002277.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000002277.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000002277.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CD200R family.
CC {ECO:0000256|ARBA:ARBA00008215}.
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DR EMBL; AGCU01013637; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7F2L7; -.
DR STRING; 13735.ENSPSIP00000002277; -.
DR Ensembl; ENSPSIT00000002284.1; ENSPSIP00000002277.1; ENSPSIG00000002262.1.
DR eggNOG; ENOG502S9IV; Eukaryota.
DR GeneTree; ENSGT00390000014496; -.
DR HOGENOM; CLU_069156_0_1_1; -.
DR OMA; TCKSPKP; -.
DR TreeFam; TF335960; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0009986; C:cell surface; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR GO; GO:0150077; P:regulation of neuroinflammatory response; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR040012; CD200R.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR21462:SF2; CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 1; 1.
DR PANTHER; PTHR21462; CELL SURFACE GLYCOPROTEIN OX2 RECEPTOR PRECURSOR; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 233..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 42..147
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 322 AA; 35743 MW; A14A3953D5D631E8 CRC64;
MVTRGSQARN STGADTKCCQ GYNSSIDKKE DTQNLVQWTS LPNGNTNVHG IAGDSVNLIC
VNTSSLVDIT SVIWKIIPKT GEPCTLAYRT DKNKTDRINC SERIDWKSSP DTDTALQIQN
VILSDEGIYI CEFVSAEGNF NQNYTLIVLV PPEMNLICDS NRDAVCKAAA GKPAAQIFWA
PRGDSKNETE NHPNGTVTVL STYSFNKTGV TCTVSHPAWN MNQSKECKPV HVWTIWLCAI
AAGILGILFI LTSIFLWKLH HGRLGYKSER PETAPTHNVQ DSNEQHELEP YASYVQKENT
IYSTMYEVVE CEHPPPRLQS AT
//
