ID K7F3H8_PELSI Unreviewed; 1331 AA.
AC K7F3H8;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Zinc finger protein 521 {ECO:0000313|Ensembl:ENSPSIP00000002588.1};
GN Name=ZNF521 {ECO:0000313|Ensembl:ENSPSIP00000002588.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000002588.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000002588.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01113927; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01113928; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01113929; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01113930; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01113931; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01113932; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01113933; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01113934; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01113935; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01113936; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 13735.ENSPSIP00000002588; -.
DR Ensembl; ENSPSIT00000002597.1; ENSPSIP00000002588.1; ENSPSIG00000002538.1.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000159287; -.
DR HOGENOM; CLU_004018_0_0_1; -.
DR OMA; HCESAFS; -.
DR TreeFam; TF331504; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0019904; F:protein domain specific binding; IEA:Ensembl.
DR GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 14.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24406; TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED; 1.
DR PANTHER; PTHR24406:SF30; ZINC FINGER PROTEIN 423; 1.
DR Pfam; PF00096; zf-C2H2; 4.
DR Pfam; PF13912; zf-C2H2_6; 6.
DR Pfam; PF12874; zf-met; 2.
DR SMART; SM00355; ZnF_C2H2; 30.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 11.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 26.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 24.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 138..165
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 166..193
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 194..221
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 222..249
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 266..294
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 301..329
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 330..357
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 457..485
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 497..525
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 533..561
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 654..676
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 684..706
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 714..738
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 742..770
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 772..800
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 803..830
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 829..852
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 906..933
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 950..977
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 979..1006
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1158..1186
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1245..1272
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1276..1304
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1306..1331
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 101..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 378..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 883..902
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1188..1208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..394
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1331 AA; 150347 MW; 10A84EEAD680ACBD CRC64;
MSRRKQAKPR SLKVEENETE DQQAGVGQIT AQTDANCKLE EKAEDGEVID CKKRPEEGEE
LEEEAVHSCD SCLQVFESLS DITEHKINQC QLTDGVDIED DPTCSWPASS PSSKDQTSPS
HGEGCDFGEE EGGPGLPYPC QFCDKSFSRL SYLKHHEQSH SDKLPFKCTY CSRLFKHKRS
RDRHIKLHTG DKKYHCSECD AAFSRSDHLK IHLKTHTSNK PYKCAICRRG FLSSSSLHGH
MQVHERNKDG SQSASRMEEW KMKDTQKCSQ CEEGFDFPED LQKHIAECHP ECSPNEDRAA
LQCVYCHELF VEESSLVNHM EQVHNGEKKN SCSVCSENFH TVEELYSHMD SHQQPESCNH
SNSPSLVTVG YTSVSSTTPD SNLSVDSSTM VETAPPITKG RGRKRAAQQV PDITGPSNKQ
AKVTYSCIYC NKQLFSSLAV LQIHLKTMHL DKPEQAHICQ YCLEVLPSLY NLNEHLKQVH
EAPDPALIVS TMPAMVYQCN FCSEVFNDLN TLQEHIRCSH GFANPAAKDS NAFFCPHCYM
GFLTDSSLEE HIRQVHCDLS SSRFGSPVLG TPKDPVVEVY SCSYCTNSPI FNSVLKLNKH
IKENHKNIPL ALNYIHNGKK SRALSPLSPV TIEQTSLKMM QAVGGAPPRP AGEYVCNQCG
AKYTSLDGFQ THLKTHLDTV LPKLTCPQCN KEFPNQESLL KHVTIHFMIT STYYICESCD
KQFTSVDDLQ KHLLDMHTFV FFRCTLCQEV FDSKVSIQLH LAVKHSNEKK VYRCTSCNWD
FRNETDLQLH VKHNHLENQG KVHKCIFCGE SFGTEVELQC HITTHSKKYN CKFCSKAFHA
IILLEKHLRE KHCVFETKTP NCGTNGASEQ VQKEEVELQT LLTNSQESHN SHDGSEEDVD
TSEPMYGCDI CGAAYTMETL LQNHQLRDHN IRPGESAIVK KKAELIKGNY KCNVCSRTFF
SENGLREHMQ THLGPVKHYM CPICGERFPS LLTLTEHKVT HSKSLDTGNC RICKMPLQSE
EEFLEHCQMH PDLRNSLTGF RCVVCMQTVT STLELKIHGT FHMQKTGNGS SVQSTGRAQH
LQKLYKCASC LKEFRSKQDL VKLDINGLPY GLCAVCVNLS KSGSPSVNIP SSSNRQGLGQ
NENLSSIENK SKAGGLKTRC SSCNVKFESE SELQNHIQSI HRELVPDSNS TQLKTPQVSP
MPRISPSQSD EKKTYQCIKC QMVFYNEWDI QVHVANHMID EGLNHECKLC NQTFDSPAKL
QCHLIEHSFE GMGGTFKCPV CFTVFVQANK LQQHIFSAHG QEDKIYDCTQ CPQKFFFQTE
LQNHTMTQHS S
//
