ID K7F3L8_PELSI Unreviewed; 356 AA.
AC K7F3L8;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Phosphoribosyl pyrophosphate synthetase associated protein 1 {ECO:0000313|Ensembl:ENSPSIP00000002628.1};
GN Name=PRPSAP1 {ECO:0000313|Ensembl:ENSPSIP00000002628.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000002628.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000002628.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the ribose-phosphate pyrophosphokinase family.
CC {ECO:0000256|ARBA:ARBA00006478}.
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DR EMBL; AGCU01174253; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01174254; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01174255; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01174256; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01174257; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01174258; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01174259; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01174260; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01174261; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006136538.1; XM_006136476.2.
DR RefSeq; XP_006136539.1; XM_006136477.1.
DR AlphaFoldDB; K7F3L8; -.
DR STRING; 13735.ENSPSIP00000002628; -.
DR Ensembl; ENSPSIT00000002637.1; ENSPSIP00000002628.1; ENSPSIG00000002568.1.
DR GeneID; 102453213; -.
DR CTD; 5635; -.
DR eggNOG; KOG1503; Eukaryota.
DR GeneTree; ENSGT00950000182803; -.
DR HOGENOM; CLU_033546_0_0_1; -.
DR OMA; GIIACPG; -.
DR OrthoDB; 276387at2759; -.
DR TreeFam; TF106367; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
DR GO; GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 2.
DR InterPro; IPR029099; Pribosyltran_N.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR005946; Rib-P_diPkinase.
DR NCBIfam; TIGR01251; ribP_PPkin; 1.
DR PANTHER; PTHR10210:SF28; PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE-ASSOCIATED PROTEIN 1; 1.
DR PANTHER; PTHR10210; RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER; 1.
DR Pfam; PF14572; Pribosyl_synth; 1.
DR Pfam; PF13793; Pribosyltran_N; 1.
DR SMART; SM01400; Pribosyltran_N; 1.
DR SUPFAM; SSF53271; PRTase-like; 2.
PE 3: Inferred from homology;
KW Nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022727};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 15..126
FT /note="Ribose-phosphate pyrophosphokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13793"
SQ SEQUENCE 356 AA; 39284 MW; F6C1BB8C48E28E57 CRC64;
MNAARSGYRV FSANSTAACT ELAKKITERL GAELGKSVVY QETNGETRVE IKESVRGQDI
FIIQTIPRDV NTAVMELLIM AYALKTSCAK NIIGVIPYFP YSKQSKMRKR GSIVCKLLAS
MLAKAGLTHI ITMDLHQKEI QGFFSFPVDN LRASPFLLQY IQEEIPNYRN AVIVAKSPDA
AKRAQSYAER LRLGLAVIHG EAQCTEQDMD DGRHSPPTVK NTTVHSGLEL PLMMAKEKPP
ITVVGDVGGR IAIIVDDIID DVESFVAAAD ILKERGAYKI FVMATHGLLS ADAPRLIEES
AVDEVVVTNT VPHEVQKLQC PKIKTVDISL ILSEAIRRIH NGESMAYLFR NITVDD
//
