ID K7F684_PELSI Unreviewed; 601 AA.
AC K7F684;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=FERM domain containing 1 {ECO:0000313|Ensembl:ENSPSIP00000003544.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000003544.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000003544.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01085566; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01085567; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01085568; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01085569; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006122989.1; XM_006122927.1.
DR AlphaFoldDB; K7F684; -.
DR Ensembl; ENSPSIT00000003562.1; ENSPSIP00000003544.1; ENSPSIG00000003374.1.
DR GeneID; 102454885; -.
DR KEGG; pss:102454885; -.
DR CTD; 79981; -.
DR GeneTree; ENSGT00940000155517; -.
DR HOGENOM; CLU_036910_1_1_1; -.
DR OrthoDB; 3795301at2759; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13185; FERM_C_FRMD1_FRMD6; 1.
DR CDD; cd17197; FERM_F1_FRMD1; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR041781; FRMD6-FERM_C.
DR InterPro; IPR047145; FRMD6-like.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR13429; FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY; 1.
DR PANTHER; PTHR13429:SF7; FERM DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 15..319
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 345..395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 419..446
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 601 AA; 68389 MW; C6C1A23AAA85187F CRC64;
MSRSLLQSRM QQEYRNVCVL LPNREQLSVT IGVKATGQEL FQQVCDLVKI KDPHFFGLSI
IKNNEYVFMD LEQKLSKYFS KEWKKETNKG TEKFTPPFVA FFRVQYYVEN GRVISDKAAR
HLYYCHLKEQ VLRSRCSHKE EIYFLLAAYS LQADLGSYAE NVHVGKYFEP QAYFPQWIIA
KRGSDYILKH APEIHQEQKG LSTKDAILQF IKESCLLEDV PVHYFRLQKD KKEDRPTVVL
GLTLKGIHIY QEVNHVRQLL YDFPWSHIGK LAFLGKKFEI QPDGLPSARK LVYYTGCPFR
SRHLLQLLSN SHRLFLNVQP VLKQIQKLEE VEEKKRYRES YISDTLEMDL DPSDKHSHGS
GSSGGSQRVN RLSRQSTGSH GSSHTSGIEA DSRHRMSVEM SVDEPFSIER VHRKEKSCSS
TVSCGSSGID SGGKGRVEED SQDDEVELAV DDPVERNQLE EAAEGECASP LALDALCCQA
LKKKPLPVVQ VTLIQMRGQS VESLHQVRQP KGRSCADQHS QSLDDIRLYK HQHPPISSTL
SSDTSHSYTF GCALDDKLAS YGCVYSTADC KTKSALYGKR SMNCLSLDLL GEDQLPEEFV
V
//
