ID K7F6A7_PELSI Unreviewed; 620 AA.
AC K7F6A7;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Keratin, type II cytoskeletal cochleal {ECO:0000313|Ensembl:ENSPSIP00000003567.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000003567.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000003567.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGCU01084180; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01084181; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01084182; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01084183; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01084184; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01084185; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01084186; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01084187; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01084188; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01084189; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7F6A7; -.
DR Ensembl; ENSPSIT00000003586.1; ENSPSIP00000003567.1; ENSPSIG00000003387.1.
DR GeneTree; ENSGT00940000155862; -.
DR HOGENOM; CLU_012560_6_0_1; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR032444; Keratin_2_head.
DR InterPro; IPR003054; Keratin_II.
DR PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45616:SF39; KERATIN, TYPE II CYTOSKELETAL 6A; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF16208; Keratin_2_head; 1.
DR PRINTS; PR01276; TYPE2KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 3.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 181..493
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 599..620
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 178..205
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 235..325
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 391..471
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 620 AA; 63379 MW; 93E109104BFF2D9D CRC64;
GKTCVAGGGG GGGGRRCFSS ASAICSLGGG RASGGGAGGG FGFGGFGFGG GAGAGGGGLG
VGFGGGRSPA GFGGGGAGGG GGAGFGGGFG GFGLGGGGGG FGYGGGSSLG LGGGSGGLGY
GGAGAAGGYG FAGAGFGGGG GGPGFPVCPP GGIQEVTINQ SLLKPLNVEL DPSIQRVKQE
EKEQIKTLNN KFASFIDKVR FLEQQNRVLE TKWSLLQEQG QKTVMNIDPL FENYISNLRR
QLNTLTNDRG RLEGELNNMQ NVVEDFKNKY EDEINRRTVA ENDFVTLKKD VDAAYMNKVE
LGAKVDSLTD EINFLRALYE TELNQMQQHV GDTSVVLSMD NNRSLDLDSI IREVKAQYED
IANRSRAEAE SWYQTKYEEL QLTAGRHGDD LRNTKHEISE LNRSIQRLRA EIDGVKRQCA
NLQAAITEAE ERGELALKDA REKLADLEDA LQKAKQDMAR QLREYQELMN VKLALDIEIA
TYRKLLEGEE SRVKRGSGVC VGGGSFSSGS GRGVGGLSLG GGSGSRSGYA YGLGYGGMGG
RIREAGYGLG GGGSSYNSGS GLSLGSGLGN ASGLAYAAGL GVGGSSFSTS SGRGLVGGYS
SGGGSSSSVK IVSKTTSTKK
//
