ID K7F7E7_PELSI Unreviewed; 1237 AA.
AC K7F7E7;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Neurexin 2 {ECO:0000313|Ensembl:ENSPSIP00000003957.1};
GN Name=NRXN2 {ECO:0000313|Ensembl:ENSPSIP00000003957.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000003957.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000003957.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; AGCU01142840; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01142841; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01142842; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01142843; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01142844; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01142845; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01142846; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01142847; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01142848; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01142849; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7F7E7; -.
DR Ensembl; ENSPSIT00000003977.1; ENSPSIP00000003957.1; ENSPSIG00000003726.1.
DR GeneTree; ENSGT00940000155978; -.
DR HOGENOM; CLU_001710_0_1_1; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR CDD; cd00053; EGF; 1.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00110; LamG; 6.
DR Gene3D; 2.60.120.200; -; 6.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR15036:SF52; NEUREXIN-2; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF02210; Laminin_G_2; 6.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00282; LamG; 6.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 6.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS50025; LAM_G_DOMAIN; 6.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..1237
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003904757"
FT DOMAIN 31..207
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 203..241
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 287..469
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 476..668
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 672..709
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 714..886
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 900..1075
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1078..1115
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1119..1237
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
SQ SEQUENCE 1237 AA; 136023 MW; EA2A33F4366BBBA0 CRC64;
MQLGAMARLG ALMPLVLLMG ALLGPGAGGA ALEFGGATGQ WARYARWDAS SLGELSFSLK
TNVSWALVLY LDDGGNCDFL ELMIAEGRLR LRFTISCAEP ANLHLETPVD DDRWHMVLLT
RNYRETMLVV DGEAKVAEVK SKRRDMAVES DLFVGGIPPD VRLSALTLST VKYEVPFKGL
VANLKVGDMP PALLGSQGIR SDTEYLCTKQ NPCAHGGLCS VLNGEVQCDC SMTGFQGKFC
SEEEHTMEGP AHLTLNSQVG SILYSEGGEG RGASEVQHTS KGKEEYVATF KGNEFFCYDL
SHNPIQSSTD EITLSFRTLQ RNGLMLHTGK SADYVNLSLK SGAVWLVINL GSGAFEALVE
PVNGKFNDNN WHDIRVTRNL RQVTISVDGI LTTTGYTQED YTMLGSDDFF YIGGSPNTAD
LPGSPVSNNF MGCLKDVVYK NNDFKLELSR LAKEGDPKMK INGDLVFRCE NVAALDPVTF
ESPEAYISLP KWNTKKTGSI SFDFRTTEPN GLLLFSHGRL QPPRESRAER PHKADYFAME
LLDGHLYLLL DMGSGGIKMR ASNKKVNDGE WCHVDFQRDG RKGSISVNSR SIPFLASGES
EILDLDSEMY LGGLPENRLD LILPPEVWTA FLNYGYVGCV RDLFIDGKSR DVRRLAEVQS
VPGVSSFCSR ETLKQCSSAP CRNGGVCREG WNRFICDCLG TGYLGRVCER EATVLSYDGS
MYMKIMLPGV MHTEAEDVSL RFMSQRAYGF MLATTSKESA DTLRLELDGG QMKLTVNLDC
VRIGCNPSKG PETLFAGHKL NDNEWHTVRV VRRGKSLQLS VDNVTVEGQM AGAHTRLEFH
NIETGIMTER RFISVVPSNF IGHLSSLVFN GLPYMDLCKN GDISYCELNA RFGLRSIIAD
PVTFKSRSSY LALATLQAYA SMHLFFQFKT TATDGLILFN SGNGNDFIVV ELVKGYIHYV
FDLGNGPSLM KGNSDKPVND NQWHNVIVSR DTSNVHTLKI DSRTVTQHSN GARNLDLKGE
LYIGGLSKNM FNNLPKLVAS RDGFQGCLAS VDLNGRLPDL IADALHRIGQ VERGCDGPST
TCTEDSCANQ GVCLQQWDGY TCDCTMTSYG GPVCNDPGTT YIFGKGGALI TYTWPPNDRP
STRADRLAVG FSTHQKNAIL VRVDSASGLG DYLQLHIDQG TIGVIFNVGT DDITIEETNA
MVNDGKYHVV RFTRSGGNAT LQVDNWPVNE RYPAEHR
//
