ID K7F9L3_PELSI Unreviewed; 1240 AA.
AC K7F9L3;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Zinc finger and AT-hook domain containing {ECO:0000313|Ensembl:ENSPSIP00000004723.1};
GN Name=ZFAT {ECO:0000313|Ensembl:ENSPSIP00000004723.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000004723.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000004723.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01090565; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01090566; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01090567; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01090568; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01090569; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01090570; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01090571; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01090572; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01090573; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01090574; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7F9L3; -.
DR STRING; 13735.ENSPSIP00000004723; -.
DR Ensembl; ENSPSIT00000004749.1; ENSPSIP00000004723.1; ENSPSIG00000004396.1.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000156658; -.
DR HOGENOM; CLU_008355_0_0_1; -.
DR OMA; ACELCDH; -.
DR TreeFam; TF350017; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IEA:Ensembl.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 11.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24388; ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR24388:SF73; ZINC FINGER PROTEIN ZFAT; 1.
DR Pfam; PF00096; zf-C2H2; 5.
DR Pfam; PF13909; zf-H2C2_5; 1.
DR SMART; SM00355; ZnF_C2H2; 19.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 8.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 10.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 13.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 117..147
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 269..296
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 297..324
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 352..380
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 402..429
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 430..452
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 456..484
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 740..767
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 828..851
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 907..934
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 935..962
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 964..991
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 992..1020
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 75..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 144..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 662..699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..183
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1240 AA; 140008 MW; 1F971F39AD53C81F CRC64;
LSLSFSGINS IFMCKLCNLF SPNQSELLSH VSEKHAEEGI NVDDIVIPLR PLTAPTNASK
SGEELLVVKR KRGRPKGSTK KFCADEESAE NNCIPSEETQ QGPEEGTELT EVLPGNLECR
KCSRKFSNPR QLRKHICIIV SNEGEEEEDP GNDSDVDLDR KEDEREKTPK RPRIQKTEKA
LSTKEGDQIS GAKNPIISVV LTAHEAIPGA TKIVPVEAVP PETESAANPE PALPDTSQRR
GYQEYAIQQT PYEQPMKSSR LGPTQLKIFT CEYCNKVFKF KHSLQAHLRI HTNEKPYKCS
YCSYASAIKA NLNVHMRKHT GEKFSCDYCA FTCLSKGHLK VHIERVHKKI KQHCRFCKKK
YSDVKNLIKH IKETHDLQDK KVKDVFDELR LMTREGKRQL LYDCNICERK FKNELDRDRH
MLVHGDERPF ACELCGHGAT KYQALELHVR KHPFVYVCSV CSKKFVSSVR LRAHIKELHG
NLQETSVFNS SINQSFCLLE PGGDIQQEAI GEQLSQTADE FVSLSAKVLS IPKQSTYEDD
SNAIDRSHND QHGGLLKIET ALSLEFENSL AKNAPEPQCQ PPTDQAAPAP QSDCFLLKNA
TRASDELKAS CENVQEVNHD SSVNMQGEEI QLLLSGGKKS NINQNDIAIE NLSVSEEKTQ
PICFSESETS KSPNQNTDDS TNPPPVSEGS TAFSPQLDSL NMASDNRSGA VAFMQILDSL
QKRQMNTDLC EKIRKVYGDL ECEYCGKLFW YQVHYDMHVR THTREHLYYC SQCNYSSITK
NCLKRHVIQK HSNILLKCPT EDCDYSTPDK YKLQAHLKVH TELDKKSYSC PVCEKSFSED
RLIKSHIKTN HPEVSMSTIS EILGRRVQLK GLIGKRAVKC PYCDFYFMKN GSDLQRHIWA
HEGVKPFKCS LCEYATRSKS NLKAHMNRHS TEKTHLCDMC GKKFKSKGTL KSHKLLHTAD
GKQFKCTVCD YTAAQKPQLL RHMEQHVSFK PFRCAHCHYS CNISGSLKRH YNRKHPNEEY
VNVGTGERSA DTFLQSGGIK CPVCSFVYGT KWEFNRHLKN KHGLKLVEHD GEAKWELTTE
ISEESSTQYL HITDTEDVQG TQAAVAALQD LRYTSENGER LDPTAVNILQ QIIELGSETH
DAAAVASVVT MAPGTVTVVK QVKEEEQSAN HTVMIQETLQ QASVELAEQH HLVVSSDEVE
GIETVTVYTQ GGEPSEFIVY VQEAMQPVEE ETVEQSVQEI
//
