ID K7FA60_PELSI Unreviewed; 228 AA.
AC K7FA60;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Proteasome 26S subunit, ATPase 5 {ECO:0000313|Ensembl:ENSPSIP00000004920.1};
GN Name=PSMC5 {ECO:0000313|Ensembl:ENSPSIP00000004920.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000004920.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000004920.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AGCU01164551; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01164552; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01164553; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01164554; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01164555; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01164556; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7FA60; -.
DR STRING; 13735.ENSPSIP00000004920; -.
DR Ensembl; ENSPSIT00000004948.1; ENSPSIP00000004920.1; ENSPSIG00000004599.1.
DR eggNOG; KOG0728; Eukaryota.
DR GeneTree; ENSGT01020000230346; -.
DR HOGENOM; CLU_000688_2_5_1; -.
DR OMA; WLEPARE; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0005838; C:proteasome regulatory particle; IEA:Ensembl.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140297; F:DNA-binding transcription factor binding; IEA:Ensembl.
DR GO; GO:0140296; F:general transcription initiation factor binding; IEA:Ensembl.
DR GO; GO:0031531; F:thyrotropin-releasing hormone receptor binding; IEA:Ensembl.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:Ensembl.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032501; Prot_ATP_ID_OB_2nd.
DR PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR23073:SF166; 26S PROTEASOME REGULATORY SUBUNIT 8; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF16450; Prot_ATP_ID_OB_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 65..120
FT /note="Proteasomal ATPase second OB"
FT /evidence="ECO:0000259|Pfam:PF16450"
FT DOMAIN 178..220
FT /note="ATPase AAA-type core"
FT /evidence="ECO:0000259|Pfam:PF00004"
FT COILED 20..61
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 228 AA; 25468 MW; 1AE0EFACA5252AED CRC64;
MEMDEGKGGT GLRQYYLSKI EELQLIVNEK SQNLRRLQAQ RNELNAKVRL LREELQLLQE
QGSYVGEVVR AMDKKKVLVK VHPEGKFVVD VDKNIDINDV TPNCRVALRN DSYTLHKILP
NKVDPLVSLM MVEKVPDSTY EMIGGLDKQI KEIKEVIELP VKHPELFEAL GIAQPKGVLL
YGPPGTGKTL LARAVAHHTD CTFIRVSGSE LVQKFIGEGA PMGRGTAD
//
