ID K7FGM8_PELSI Unreviewed; 459 AA.
AC K7FGM8;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Netrin G1 {ECO:0000313|Ensembl:ENSPSIP00000007188.1};
GN Name=NTNG1 {ECO:0000313|Ensembl:ENSPSIP00000007188.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000007188.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000007188.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; AGCU01063165; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01063166; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01063167; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01063168; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01063169; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01063170; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01063171; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01063172; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01063173; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01063174; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006119856.1; XM_006119794.2.
DR AlphaFoldDB; K7FGM8; -.
DR STRING; 13735.ENSPSIP00000007188; -.
DR Ensembl; ENSPSIT00000007229.1; ENSPSIP00000007188.1; ENSPSIG00000006645.1.
DR GeneID; 102459387; -.
DR KEGG; pss:102459387; -.
DR CTD; 22854; -.
DR eggNOG; KOG3512; Eukaryota.
DR GeneTree; ENSGT00940000153601; -.
DR HOGENOM; CLU_039838_1_1_1; -.
DR OMA; ANICEYR; -.
DR OrthoDB; 2916807at2759; -.
DR TreeFam; TF333945; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0098978; C:glutamatergic synapse; IEA:Ensembl.
DR GO; GO:0048787; C:presynaptic active zone membrane; IEA:Ensembl.
DR GO; GO:0098685; C:Schaffer collateral - CA1 synapse; IEA:Ensembl.
DR GO; GO:0098632; F:cell-cell adhesion mediator activity; IEA:Ensembl.
DR GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR GO; GO:0050804; P:modulation of chemical synaptic transmission; IEA:Ensembl.
DR GO; GO:2001222; P:regulation of neuron migration; IEA:Ensembl.
DR GO; GO:0150011; P:regulation of neuron projection arborization; IEA:Ensembl.
DR GO; GO:0010975; P:regulation of neuron projection development; IEA:Ensembl.
DR GO; GO:0099560; P:synaptic membrane adhesion; IEA:Ensembl.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00055; EGF_Lam; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF28; NETRIN-G1; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00053; Laminin_EGF; 1.
DR Pfam; PF00055; Laminin_N; 1.
DR SMART; SM00181; EGF; 1.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..459
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003905182"
FT DOMAIN 46..296
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 384..419
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 409..418
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 459 AA; 52210 MW; AFCC81C8F21BCDDD CRC64;
MYLSRFLSLH ALWVTVSSVM QHYPSVWGHY DVCKTQIYTE EGKVWDYMAC QPEAKDMIKY
VKVTLDPPDI TCGDPPESFC AMGNPYMCNN ECDASTNELA HPPDLMFDLE GRHPSTFWQS
TTWKDYPKPL QVNITLSWNK TIELTDNIVI TFESGRPDQM ILEKSLDYGR TWQPYQYYAT
DCLDAFHMDP KSVKDLSQHT VLEIICTEEY STGYMTNSKI IHFEIKDRFA FFAGPRLHNM
ASLYGQLDTT KKLRDFFTIT DLRIRLLRPA TGEIYVDEQH LARYFYAISD IRVYGRCKCN
LHATGCKEEN KKLFCECEHN TTGPDCGKCK KNYQGRPWSP GSYLPIPKGT ANICIPSISS
IGNPPKFDRI WPNISSLEVS KPNQANVCDK ELLQCQNGGT CLKNMRCQCP PAYTGILCEK
LKCERDPGGC SQNSGQRAVT HGPLLPLTAL LGVTGLFIF
//
