ID K7FJI1_PELSI Unreviewed; 277 AA.
AC K7FJI1;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|SMART:SM00181};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000008191.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000008191.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR EMBL; AGCU01102000; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7FJI1; -.
DR STRING; 13735.ENSPSIP00000008191; -.
DR Ensembl; ENSPSIT00000008234.1; ENSPSIP00000008191.1; ENSPSIG00000007523.1.
DR eggNOG; KOG1215; Eukaryota.
DR GeneTree; ENSGT00940000164512; -.
DR HOGENOM; CLU_1006628_0_0_1; -.
DR OMA; YHENTIR; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR CDD; cd00112; LDLa; 4.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 5.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR24270; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24270:SF67; PROLOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1-LIKE PROTEIN; 1.
DR Pfam; PF14670; FXa_inhibition; 1.
DR Pfam; PF00057; Ldl_recept_a; 5.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00192; LDLa; 5.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 5.
DR PROSITE; PS01209; LDLRA_1; 4.
DR PROSITE; PS50068; LDLRA_2; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..277
FT /note="EGF-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003901783"
FT DOMAIN 65..103
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DOMAIN 143..194
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DOMAIN 219..256
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DISULFID 29..41
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 75..93
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 87..102
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 124..139
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 144..156
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 151..169
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 163..178
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 181..193
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 188..206
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 277 AA; 29600 MW; DDD31F89BE141501 CRC64;
MERAALRLLL LALAAGCCRS LPDPGGRNCS ALHQAACGER CVPFLWLCNG EQECPDGTDE
HCEAACRGDV DAWQCDNGRC ISSSWLCDGT SDCRDGSDER NCVCEEKKIP CRGNTQCIDP
WEVCDLHEDC EDGSDEANCP QNHCLPGQWQ CKNKVCIMED WKCNGVNNCG DSSDEDICAH
CPEGMILCDE GKCILGALMC NGAEDCLDGT DELSTCGKNC SVDNGGCVET CTETSWGVRC
SCGAGWELQA DGQNCTGMAT SAPVEQSQGG VSRATSK
//
