ID K7FL91_PELSI Unreviewed; 309 AA.
AC K7FL91;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Chromosome 12 open reading frame 66 {ECO:0000313|Ensembl:ENSPSIP00000008801.1};
GN Name=KICS2 {ECO:0000313|Ensembl:ENSPSIP00000008801.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000008801.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000008801.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01134333; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01134334; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7FL91; -.
DR STRING; 13735.ENSPSIP00000008801; -.
DR Ensembl; ENSPSIT00000008847.1; ENSPSIP00000008801.1; ENSPSIG00000008044.1.
DR eggNOG; ENOG502QTBE; Eukaryota.
DR GeneTree; ENSGT00390000009583; -.
DR HOGENOM; CLU_050627_0_0_1; -.
DR OMA; RHYCHIN; -.
DR TreeFam; TF329125; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0045171; C:intercellular bridge; IEA:Ensembl.
DR GO; GO:0140007; C:KICSTOR complex; IEA:Ensembl.
DR GO; GO:0005764; C:lysosome; IEA:Ensembl.
DR GO; GO:0034198; P:cellular response to amino acid starvation; IEA:Ensembl.
DR GO; GO:0042149; P:cellular response to glucose starvation; IEA:Ensembl.
DR GO; GO:1904262; P:negative regulation of TORC1 signaling; IEA:Ensembl.
DR GO; GO:0061462; P:protein localization to lysosome; IEA:Ensembl.
DR Gene3D; 1.10.3450.30; -; 1.
DR InterPro; IPR038060; C12orf66-like_central_sf.
DR InterPro; IPR018544; KICS_2.
DR PANTHER; PTHR31581; KICSTOR COMPLEX PROTEIN C12ORF66; 1.
DR PANTHER; PTHR31581:SF1; KICSTOR SUBUNIT 2; 1.
DR Pfam; PF09404; C12orf66_like; 1.
DR SUPFAM; SSF160651; FLJ32549 C-terminal domain-like; 1.
DR SUPFAM; SSF158548; FLJ32549 domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
SQ SEQUENCE 309 AA; 35623 MW; 652763BAF9D81E4C CRC64;
MEIADFYEKM FTLSTQKFIN SEELVNILES ILKKYSSRFH HPILSPLESS FQLEVDVLAH
LLKAQAQISE WKFLPSLVNL HSAHAKLQTW GQIFERQRET KKHLFGGQSQ KAVQPPHLFL
WLMKLKNILL AKFSFYFHEA LSRQTAASEM KTLTAKTNPD YFGKISSFIR KYDAVNVSLI
FDNRGSESFQ GHGYHHPHSY REAPKGVDQY PAVVSLPSDR PVMHWPNVIM IMTDRTSDLN
SLDKVVHFYD DKVQSTYFLT RPEPHFTIVV IFEAKKSERD SHFISFLNEI SQSLKNSKAF
ASLKPGAKG
//
