ID K7FMX1_PELSI Unreviewed; 480 AA.
AC K7FMX1;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Apoptosis inducing factor mitochondria associated 3 {ECO:0000313|Ensembl:ENSPSIP00000009381.1};
GN Name=AIFM3 {ECO:0000313|Ensembl:ENSPSIP00000009381.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000009381.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000009381.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the FAD-dependent oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00006442}.
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DR EMBL; AGCU01059646; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01059647; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01059648; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01059649; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01059650; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01059651; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01059652; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01059653; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7FMX1; -.
DR Ensembl; ENSPSIT00000009428.1; ENSPSIP00000009381.1; ENSPSIG00000008461.1.
DR GeneTree; ENSGT00940000160448; -.
DR HOGENOM; CLU_003291_4_2_1; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.30.390.30; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 2.102.10.10; Rieske [2Fe-2S] iron-sulphur domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR InterPro; IPR017941; Rieske_2Fe-2S.
DR InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR PANTHER; PTHR43557; APOPTOSIS-INDUCING FACTOR 1; 1.
DR PANTHER; PTHR43557:SF8; APOPTOSIS-INDUCING FACTOR 3; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF00355; Rieske; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF55424; FAD/NAD-linked reductases, dimerisation (C-terminal) domain; 1.
DR SUPFAM; SSF50022; ISP domain; 1.
DR PROSITE; PS51296; RIESKE; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 1..47
FT /note="Rieske"
FT /evidence="ECO:0000259|PROSITE:PS51296"
SQ SEQUENCE 480 AA; 53035 MW; 594A6BE0F42D60B0 CRC64;
GVLSKGRVRC PWHGACFSIG TGDIEDFPGL DSLPKFQVKI EKEKVYIRAS KQALLTQRRT
KVMAKCISIS NYSISSTNVL IIGAGAAGLV CAETLRQEGF SDRIVMCTMD RHLPYDRPKL
SKSMDSHSDQ IILRPKEFFR TNDIEVLTET QVAAVDVKNK IAVFKDGFKM EYNKLLIATG
SMPKALSCKG KEVENVFNIR TPEDANRVVK LASSKNAVIV GASFLGMEVA AYLTEKAHSV
SVVELEEVPF KKFFGEKVGQ ALMKMFENNR VKFYMQTEVS ELREQEGKLK EVVLKSGKVL
RADVCVIGIG ASPATGFLKQ SGINIDSKGF IVVNKMMQTN IPGVFAAGDA VTFPLALRNN
KKVNIPHWQM AHMHGRIAAL NMLAHGMEIS TVPYLWTAVF GKSIRYAGHG EGFDDVIFQG
DLDELKFVAF YTKVFLFPLR DPGIIPSVSF PPAEVMASGR VIRKRDVETG DMSWLTGKGS
//
