ID K7FMZ6_PELSI Unreviewed; 621 AA.
AC K7FMZ6;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Carboxypeptidase X, M14 family member 2 {ECO:0000313|Ensembl:ENSPSIP00000009406.1};
GN Name=CPXM2 {ECO:0000313|Ensembl:ENSPSIP00000009406.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000009406.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000009406.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the peptidase M14 family.
CC {ECO:0000256|ARBA:ARBA00005988}.
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DR EMBL; AGCU01172457; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172458; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172459; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172460; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172461; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172462; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172463; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172464; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172465; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01172466; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7FMZ6; -.
DR Ensembl; ENSPSIT00000009453.1; ENSPSIP00000009406.1; ENSPSIG00000008503.1.
DR GeneTree; ENSGT00940000156414; -.
DR HOGENOM; CLU_006722_4_0_1; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00057; FA58C; 1.
DR CDD; cd03869; M14_CPX_like; 1.
DR CDD; cd11308; Peptidase_M14NE-CP-C_like; 1.
DR Gene3D; 2.60.40.1120; Carboxypeptidase-like, regulatory domain; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR008969; CarboxyPept-like_regulatory.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR000834; Peptidase_M14.
DR PANTHER; PTHR11532:SF45; INACTIVE CARBOXYPEPTIDASE-LIKE PROTEIN X2; 1.
DR PANTHER; PTHR11532; PROTEASE M14 CARBOXYPEPTIDASE; 1.
DR Pfam; PF13620; CarboxypepD_reg; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR Pfam; PF00246; Peptidase_M14; 1.
DR PRINTS; PR00765; CRBOXYPTASEA.
DR SMART; SM00231; FA58C; 1.
DR SMART; SM00631; Zn_pept; 1.
DR SUPFAM; SSF49464; Carboxypeptidase regulatory domain-like; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00132; CARBOXYPEPT_ZN_1; 1.
DR PROSITE; PS01285; FA58C_1; 1.
DR PROSITE; PS01286; FA58C_2; 1.
DR PROSITE; PS50022; FA58C_3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 1..158
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
SQ SEQUENCE 621 AA; 71343 MW; 08A2F61C3B3B59A8 CRC64;
CPPLGLETLK ITDFQLHAST VKRYGLGAHR GRLNIQAGVN ENDFYDGAWC AGRNDPYQWI
ELDARRLTKF TGIITQGRNS LWLSDWVTSY KVMVSNDSHA WITVKNGSGD MIFEGNSEKE
IPVLNELPVP IVARYIRINP RSWYEEGSIC MRLEILGCPL PDPNNYYHRR NEMTTTDDLD
FKHHNYKEMR QLMKVVNEMC PNITRIYNIG KSHQGLKLYA VEISDNPGEH EVGEPEFRYI
AGAHGNEVLG RELILLLMQF MCQEYLAGNQ RIIHLIEDTR IHLLPSVNPD GYEMAYEVGS
ELGGWSLGRW TKDGIDINNN FPDLNTMLWE AEDRKKFQRK VPNHHIPIPE WYLSENTTVA
VETRAVIAWM EKIPFVLGGN LQGGELVVAY PYDMVRSTWK TQEHTPTPDD HVFRWLAYSY
ASTHRLMTDA RRRVCHTEDF QKEDGTVNGA SWHTVAGSIN DFSYLHTNCF ELSIYVGCDK
YPHESELPEE WENNRESLIV FMEQVHRGIK GMVRDLSGKG IPNAIISVEG VNHDIRTASD
GDYWRLLNPG EYVVTAKAEG YTSSTKNCAV GYDMGATLCD FTISKTNLAR IKEIMEKFGK
QPISLSIRRL RQRARQRRQQ R
//
