ID K7FPR2_PELSI Unreviewed; 505 AA.
AC K7FPR2;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Band 4.1-like protein 5 {ECO:0000256|ARBA:ARBA00023841};
DE AltName: Full=Erythrocyte membrane protein band 4.1-like 5 {ECO:0000256|ARBA:ARBA00030226};
GN Name=EPB41L5 {ECO:0000313|Ensembl:ENSPSIP00000010022.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000010022.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000010022.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Plays a role in the formation and organization of tight
CC junctions during the establishment of polarity in epithelial cells.
CC {ECO:0000256|ARBA:ARBA00023750}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004202};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}. Photoreceptor inner segment
CC {ECO:0000256|ARBA:ARBA00004437}.
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DR EMBL; AGCU01193631; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193632; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193633; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193634; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193635; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193636; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193637; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193638; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193639; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01193640; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7FPR2; -.
DR Ensembl; ENSPSIT00000010073.1; ENSPSIP00000010022.1; ENSPSIG00000008929.1.
DR GeneTree; ENSGT00940000156332; -.
DR HOGENOM; CLU_003623_1_0_1; -.
DR OMA; WPPDAAG; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0001917; C:photoreceptor inner segment; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13186; FERM_C_NBL4_NBL5; 1.
DR CDD; cd17205; FERM_F1_EPB41L5; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF15; BAND 4.1-LIKE PROTEIN 5; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 43..327
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 352..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 505 AA; 57965 MW; CECC1D1DB16AE3EB CRC64;
MLRFFRRTLG RRSMRKHVEK ERLREAQRAV THIPAAGDAK SIITCRVSLL DGTDVSVDLP
KKAKGQHLFE QIMYHLDLIE NDYFGLRFMD SAQVAHWLDN TKSIKKQVKI GPPYCLHLRV
KFYSSEPNNL REELTRYLFV LQLKQDILSG KLECPFDTTV QLAAYTLQAE LGDYDPAEHI
PDLVSEFRFV PTQTEEMELA IFEKWKEYRG QTPAQAETNY LNKAKWLEMY GVDMHIVKAR
DGNDYSLGLT PTGVLVFEGD TKIGLFFWPK ITRLDFKKNK LTLVVVEDDE QGKEQEHTFV
FRLDHPKACK HLWKCAVEHH AFFRLRGPVQ KGSSRSSFIR LGSRFRYSGK TEYQTTKTNK
ARRSASFERR PSKRYSRRTL QMKANVAKLE ETSIPNNVLN QNNGSQKSWN AKPTLPVMTV
SSGPVLVEIE NLPRSPGASL QDKKWPLDAA DRCQHGGSVW NAWAPSSTHS ADRHYTAFVH
ERNVKNSGIH SDAIGYAVQT TMTDL
//
