ID K7FPW8_PELSI Unreviewed; 370 AA.
AC K7FPW8;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Leucine rich repeats and transmembrane domains 2 {ECO:0000313|Ensembl:ENSPSIP00000010078.1};
GN Name=LRTM2 {ECO:0000313|Ensembl:ENSPSIP00000010078.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000010078.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000010078.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01168444; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01168445; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006135522.1; XM_006135460.2.
DR RefSeq; XP_014435204.1; XM_014579718.1.
DR AlphaFoldDB; K7FPW8; -.
DR STRING; 13735.ENSPSIP00000010078; -.
DR Ensembl; ENSPSIT00000010129.1; ENSPSIP00000010078.1; ENSPSIG00000009149.1.
DR GeneID; 102463202; -.
DR KEGG; pss:102463202; -.
DR CTD; 654429; -.
DR eggNOG; KOG0619; Eukaryota.
DR GeneTree; ENSGT00940000157572; -.
DR HOGENOM; CLU_038584_1_0_1; -.
DR OMA; QISWIAC; -.
DR OrthoDB; 4193933at2759; -.
DR TreeFam; TF351114; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0051965; P:positive regulation of synapse assembly; IEA:Ensembl.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR24369; ANTIGEN BSP, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR24369:SF175; LEUCINE RICH REPEATS AND TRANSMEMBRANE DOMAINS 2; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF01462; LRRNT; 1.
DR SMART; SM00369; LRR_TYP; 4.
DR SMART; SM00082; LRRCT; 1.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..370
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003902009"
FT TRANSMEM 307..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 38..72
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
FT DOMAIN 198..251
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
FT REGION 261..294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 351..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 370 AA; 41244 MW; 3548532799CB4590 CRC64;
MLPGSLGHWW RNKFSMRWQQ TCLLACWLSL CAADSLFTCP SSCQCNSGSL EVDCSGLGLS
SIPSDIPTNT RIFLFLNNKL STLPGPVFSN LSALQRLDLS NNFLDQLPQN IFSDLGNLTE
LQLRNNSIRT LDKDLLQHMA LLRQLDLSIN GLAQIPSGIF DDLPALRLLS LRSNRLHSLD
RVTFEPLVSL QQLQVGDNPW ECDCNLREFK HWMEWFSYRG GKIDQLACTL PKELKGKDMR
MVPMEMFNYC SQLEDENGSV VLDNSGPPCT KGSPTPSKSK SGPEPEVEPS VGCPQKQKYR
PVSVRRAIGT VIIAGVVCGI VCIMMVVAAA YGCIYASLMA KYHRELKKRQ PLMGDTEGEH
EEQKQISSVA
//
