ID K7FQG0_PELSI Unreviewed; 961 AA.
AC K7FQG0;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=HEAT repeat-containing protein 6 {ECO:0000256|ARBA:ARBA00015263};
GN Name=HEATR6 {ECO:0000313|Ensembl:ENSPSIP00000010270.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000010270.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000010270.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGCU01199385; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01199386; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01199387; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01199388; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01199389; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7FQG0; -.
DR STRING; 13735.ENSPSIP00000010270; -.
DR Ensembl; ENSPSIT00000010322.1; ENSPSIP00000010270.1; ENSPSIG00000009325.1.
DR eggNOG; KOG4535; Eukaryota.
DR GeneTree; ENSGT00390000016675; -.
DR HOGENOM; CLU_007141_1_0_1; -.
DR OMA; VRTNAAW; -.
DR TreeFam; TF324244; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR025283; DUF4042.
DR PANTHER; PTHR13366:SF0; HEAT REPEAT-CONTAINING PROTEIN 6; 1.
DR PANTHER; PTHR13366; MALARIA ANTIGEN-RELATED; 1.
DR Pfam; PF13251; DUF4042; 1.
DR Pfam; PF13646; HEAT_2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 195..376
FT /note="DUF4042"
FT /evidence="ECO:0000259|Pfam:PF13251"
FT REGION 108..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 384..419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 384..400
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 961 AA; 105722 MW; 16887A6F373EB418 CRC64;
MANLCLSVPG QPYLDDSYRS LCFQTFLNVL QSSKASDIDD ITFCMLLQNA LKGIQSLLNG
GKMKLIQTDE LGSLLAVLKK CIYYGLPGLN VEVPAVLYPT PLPQYDGRSP VKQEQLELST
IKQTGTRRKK SKGKQKKGQL GEEVKEELED AAYMPAGKGH LSSCCPTWKR ISSSESEYSD
AEGGIQSKMR SYQAKVRQGA LACLLSTIKS IEKKVLYGYW SAFVPDTPGI GSPQSVSLMT
IALKDPSPKT RACALQVLSA ILEGSKQFLS VAEDAHDHKR AFTPFSVTIA SSIRELHRCL
LLALVAESSS QTLTQIIKCL ANLVSNAPYS RLKPGLLTRV WNQIKPYVHH KDVNVRVSSL
TLLGAVVSAQ APSPEVQLLL QQPNSSGLSN SGTATPHRLS SSEWWRRAPP TQGEPTGNWE
SSSLEPCWLI RLCISTAVLP REDSYSDSDA SFTAGTVYEP SPVRLESLQV LALLVKGYFP
VAQSYLLELG EVACKCMEET DPSIQLHGAK LLEELGTGII QQHKPDSTIS VSQRVPVNLV
VTFWTMMLNG PLPGALQNAQ HPTLQTSACD ALSSILPEAF SILQDDRQIL CITLLLGLTH
SENPLVKAAA ARALGVYILF SCLRQDVMFV ADTANAVLNS LHDKSPNVRA KAAWSLGNLT
DTLIVNMEVM GQSFQEEFSD LLLLKMLRSA TEATKDKDKV KSNAVRALGN LLHFLQPYHI
VKPRFSEAIK ESIQALISTV QGEATMKVRW NACYALGNVF KNPALPLGEA PWTAQAYNAL
TSVVKSCKNF KVRIKSAMAL SIPTKRERYG TTDQFSQIWS ALVIALQKSE DTEDFLEFKY
SASLRTQICQ ALIHLLSLAN STDLPFIRKT IAENGDVIRS YILQYMKSGV EDEAGIHTNS
RERERMLKTA IEHICGIEEL SEGKTRVAVA AYLEGKSVCA IEFCKREGYL VKVQDRRTPQ
L
//
