UniProt: K7FQM1

Database: UniProt
Entry: K7FQM1_PELSI

LinkDB:  K7FQM1_PELSI 
Original site:  K7FQM1_PELSI

All links

Ontology (8)   
   GO (8)   
Gene (5)   
   KEGG GENES (1)   
   NCBI-Gene (1)   
   ENSEMBL-UP (3)   
Protein sequence (7)   
   RefSeq(pep) (7)   
DNA sequence (10)   
   EMBL (10)   
Protein domain (31)   
   InterPro (18)   
   Pfam (7)   
   PROSITE (3)   
   SMART (3)   
Literature (1)   
   PubMed (1)   
All databases (62)   

Download RDF

ID   K7FQM1_PELSI            Unreviewed;      2542 AA.
AC   K7FQM1;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   SubName: Full=Talin 2 {ECO:0000313|Ensembl:ENSPSIP00000010331.1};
GN   Name=TLN2 {ECO:0000313|Ensembl:ENSPSIP00000010331.1};
OS   Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC   Trionychidae; Pelodiscus.
OX   NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000010331.1, ECO:0000313|Proteomes:UP000007267};
RN   [1] {ECO:0000313|Proteomes:UP000007267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG   Soft-shell Turtle Genome Consortium;
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000007267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX   PubMed=23624526; DOI=10.1038/ng.2615;
RA   Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA   White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA   Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA   Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA   Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT   "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT   into the development and evolution of the turtle-specific body plan.";
RL   Nat. Genet. 45:701-706(2013).
RN   [3] {ECO:0000313|Ensembl:ENSPSIP00000010331.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AGCU01115205; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01115206; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01115207; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01115208; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01115209; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01115210; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01115211; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01115212; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01115213; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01115214; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_006127396.1; XM_006127334.2.
DR   RefSeq; XP_006127397.1; XM_006127335.2.
DR   RefSeq; XP_006127398.1; XM_006127336.2.
DR   RefSeq; XP_006127399.1; XM_006127337.2.
DR   RefSeq; XP_006127400.1; XM_006127338.2.
DR   RefSeq; XP_006127401.1; XM_006127339.2.
DR   RefSeq; XP_014431119.1; XM_014575633.1.
DR   STRING; 13735.ENSPSIP00000010331; -.
DR   Ensembl; ENSPSIT00000010383.1; ENSPSIP00000010331.1; ENSPSIG00000008923.1.
DR   GeneID; 102458626; -.
DR   KEGG; pss:102458626; -.
DR   CTD; 83660; -.
DR   eggNOG; KOG4261; Eukaryota.
DR   GeneTree; ENSGT00940000154699; -.
DR   HOGENOM; CLU_000364_1_1_1; -.
DR   OMA; NMVKHSK; -.
DR   OrthoDB; 25353at2759; -.
DR   TreeFam; TF314677; -.
DR   Proteomes; UP000007267; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR   GO; GO:0005925; C:focal adhesion; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0001726; C:ruffle; IEA:InterPro.
DR   GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   CDD; cd14473; FERM_B-lobe; 1.
DR   CDD; cd10569; FERM_C_Talin; 1.
DR   CDD; cd17172; FERM_F0_TLN2; 1.
DR   CDD; cd17174; FERM_F1_TLN2; 1.
DR   CDD; cd12150; talin-RS; 1.
DR   Gene3D; 1.20.80.10; -; 1.
DR   Gene3D; 1.20.120.230; Alpha-catenin/vinculin-like; 5.
DR   Gene3D; 1.20.1410.10; I/LWEQ domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 1.20.1420.10; Talin, central domain; 7.
DR   InterPro; IPR036723; Alpha-catenin/vinculin-like_sf.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR   InterPro; IPR035963; FERM_2.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR019747; FERM_CS.
DR   InterPro; IPR000299; FERM_domain.
DR   InterPro; IPR032425; FERM_f0.
DR   InterPro; IPR018979; FERM_N.
DR   InterPro; IPR035964; I/LWEQ_dom_sf.
DR   InterPro; IPR002558; ILWEQ_dom.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR037438; Talin1/2-RS.
DR   InterPro; IPR015224; Talin_cent.
DR   InterPro; IPR036476; Talin_cent_sf.
DR   InterPro; IPR049108; Talin_R4.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   InterPro; IPR015009; Vinculin-bd_dom.
DR   PANTHER; PTHR19981; TALIN; 1.
DR   PANTHER; PTHR19981:SF34; TALIN-2; 1.
DR   Pfam; PF16511; FERM_f0; 1.
DR   Pfam; PF00373; FERM_M; 1.
DR   Pfam; PF09379; FERM_N; 1.
DR   Pfam; PF01608; I_LWEQ; 2.
DR   Pfam; PF09141; Talin_middle; 1.
DR   Pfam; PF21692; Talin_R4; 1.
DR   Pfam; PF08913; VBS; 1.
DR   SMART; SM00295; B41; 1.
DR   SMART; SM00307; ILWEQ; 1.
DR   SMART; SM01244; IRS; 1.
DR   SUPFAM; SSF109880; A middle domain of Talin 1; 1.
DR   SUPFAM; SSF47220; alpha-catenin/vinculin-like; 5.
DR   SUPFAM; SSF109885; I/LWEQ domain; 5.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF47031; Second domain of FERM; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS00661; FERM_2; 1.
DR   PROSITE; PS50057; FERM_3; 1.
DR   PROSITE; PS50945; I_LWEQ; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT   DOMAIN          88..406
FT                   /note="FERM"
FT                   /evidence="ECO:0000259|PROSITE:PS50057"
FT   DOMAIN          2294..2533
FT                   /note="I/LWEQ"
FT                   /evidence="ECO:0000259|PROSITE:PS50945"
FT   COILED          2501..2528
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   2542 AA;  271751 MW;  CFBACB377D81BCF7 CRC64;
     MVALSLKICV RQCNVVKTMQ FEPSTAVYDA CRVIRERVPE AQTGQASDYG LFLSDEDPRK
     GIWLEAGRTL DYYMLRSGDI LEYKKKQRPQ KIRMLDGSVK TVMVDDSKTV GELLVTICSR
     IGITNYEEYS LIQESIEEKK EEGTGTLKKD RTLLRDERKM EKLKAKLHTD DDLNWLDHSR
     TFREQGVDEN ETLLLRRKFF YSDQNVDSRD PVQLNLLYVQ ARDDILNGSH PVSFEKACEF
     GGFQAQIQFG PHVEHKHKPG FLDLKEFLPK EYIKQRGAEK KIFQEHKNCG EMTEIEAKVK
     YVKLARSLRT YGVSFFLVKE KMKGKNKLVP RLLGITKDSV MRVDEKTKEV LQEWPLTTVK
     RWAASPKSFT LDFGEYQESY YSVQTTEGEQ ISQLIAGYID IILKKKQSKD RFGLEGDEES
     TMLEESVSPK KSTILQQQFN RTGKVEHGSV ALPAVMRSGS SGPETFNIGS MPSPQQQVMI
     GQMHRGHMPP LTSAQQALMG TINTSMHAVH QAQSDLNEVD NLPPLGQDMA SRMWVQNKVD
     ESKHEIHSQV DAITAGTASV VNLTAGDPVD TDYTAVGCAI TTISSNLTEM SKGVKLLAAL
     MDDEVGSGED LLKAARTLAG AVSDLLKAVQ PTSGEPRQTV LTAAGSIGQA SGELLRQIGE
     NETDERFQDV LMSLAKAVAN AAAMLVLKAK NVAQVAEDMV LQNRVIAAAT QCALSTSQLV
     ACAKVVSPTI SSPVCQEQLI EAGKLVDRSV ENCVRACQAA TDDSELLKQV SAAASIVSQA
     LNDLLQHVRQ FASRGEPIGR YDQATDTIMC VTESIFSSMG DAGEMVRQAR VLAQATSDLV
     NAMRSDAEAE IDMDNSKKLL AAAKLLADST ARMVEAAKGA AANPENEDQQ QRLREAAEGL
     RVATNAAAQN AIKKKIVNRL EIAAKQAAAA ATQTIAASQN AAVSNKNTVA HQQLVQSCKN
     VADHIPQLVQ GVRGSQAQAE DLSAQLALIN SSQNFLQPGS KMVASAKAAV PTVSDQAAAM
     QLSQCAKNLA TSLAELRTAS QKAHEACGPM EIDSALNTVQ TLRNELQDAK MAALDGQLKP
     LPGETLEKCA QDLGSTSKAV GSSMAQLLTC AAQGNEHYTG VAARETAQAL KTLAQAARGV
     SASTTDPVAA HAMLDSARDV MEGSAMLIQE AKQALVAPGD AESQQRLAQV AKAVSHSLNN
     CVNCLPGQKD VDVALKSIGE SSKKLLIDSL PPSSKSFQEA QSELNQAAAD LNQSAGEVVH
     ATRGQSGELA AASGKFSDDF DEFLDAGIEM AGQAQTKEDQ IQVIGNLKNI SMASSKLLLA
     AKSLSVDPGA PNAKNLLAAA ARAVTESINQ LITLCTQQAP GQKECDNALR ELETVKGMLD
     NPNEPVSDLS YFDCIEGVME NSKVLGESMA GISQNAKIGD LLVFGECVGV ASKALCGLTE
     AAAQAAYLVG ISDPNSQAGH QGLVDPIQFA RANQAIQMAC QNLVDPASSP SQVLSAATIV
     AKHTSALCNA CRIASSKTAN PVAKRHFVQS AKEVANSTAN LVKTIKALDG DFSEDNRNKC
     RIATAPLIEA VENLTAFASN PEFVSVPAQI SMEGSRAQEP ILISAKTMLE SSALLIKTAR
     SLAINPKDPP TWSVLAGHSH TVSDSIKSLI TSIRDKAPGQ RECDYSIDGI NRCIRDIEQA
     SLAAVSQNLA TRDDISVEAL QEQLTSVVQE IGHLIDPIAT AARGEAAQLG HKVTQLASYF
     EPLILAAVGV ASKMLDHQQQ MTVLDQTKTL AESALQMLYA AKEGGGNPKA SHTHDAITEA
     AQLMKEAVDD IMVTLNEAAS EVGMVGGMVD SIAEAMNKLD EGTPPDPKGS FVDYQTTVVK
     YSKAIAVTAQ EMMTKSVTNP EELGGLASQM TNDYGHLALQ GRMAAATAEP EEIGFQIRTR
     VQDLGHGCIF LVQKAGALQI CPTDGYTKRE LIECARAVTE KVSLVLSALQ AGNKGTQACI
     TAASAVSGII ADLDTTIMFA TAGTLNAENN ESFADHRENI LKTAKALVED TKLLVSGAAS
     SPDKLAQAAQ SSATTITQLA EVVKLGAASL GSDDPETQVV LINAIKDVAK ALSDLIGATK
     GAASKPADDP SMYQLKGAAK VMVTNVTSLL KTVKAVEDEA TRGTRALEAT IECIKQELTV
     FQSKEVPEKT SSPEESIRMT KGITMATAKA VAAGNSCRQE DVIATANLSR KAVADMLTAC
     KQASYHSDVS EDVRARALRF GTECTLGYLE LLEHVLLILQ KPTPELKHPL AALSKRVAGA
     VTELIQAAEA MKGTEWVDPE DPTVIAETEL LGAAASIEAA AKKLEQLKPR AKPKQADETL
     DFEEQILEAA KSIAAATSAL VKSASAAQRE LVAQGKVGAI PANAADDGQW SQGLISAARM
     VAAATSNLCE AANASVQGHA SEEKLISSAK QVAASTAQLL VACKVKADQD SEAMRRLQAA
     GNAVKRASDN LVRAAQKAAF RKADDDDVVV KTKFVGGIAQ IIAAQEEMLK KERELEEARK
     KLAQIRQQQY KFLPTELRED EG
//

DBGET integrated database retrieval system