ID K7FR40_PELSI Unreviewed; 322 AA.
AC K7FR40;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Unc-13 homolog C {ECO:0008006|Google:ProtNLM};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000010500.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000010500.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01017436; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01017437; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01017438; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01017439; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01017440; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01017441; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01017442; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7FR40; -.
DR STRING; 13735.ENSPSIP00000010500; -.
DR Ensembl; ENSPSIT00000010553.1; ENSPSIP00000010500.1; ENSPSIG00000009526.1.
DR eggNOG; KOG1011; Eukaryota.
DR GeneTree; ENSGT00940000155174; -.
DR HOGENOM; CLU_032451_0_0_1; -.
DR OMA; RWQTASV; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0045202; C:synapse; IEA:GOC.
DR GO; GO:0019992; F:diacylglycerol binding; IEA:InterPro.
DR GO; GO:0007268; P:chemical synaptic transmission; IEA:InterPro.
DR GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR CDD; cd08395; C2C_Munc13; 1.
DR Gene3D; 1.20.58.1100; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR010439; MUN_dom.
DR InterPro; IPR014772; Munc13_dom-2.
DR InterPro; IPR027080; Unc-13.
DR PANTHER; PTHR10480; PROTEIN UNC-13 HOMOLOG; 1.
DR PANTHER; PTHR10480:SF2; PROTEIN UNC-13 HOMOLOG C; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF06292; MUN; 1.
DR SMART; SM00239; C2; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS51259; MHD2; 1.
PE 4: Predicted;
KW Exocytosis {ECO:0000256|ARBA:ARBA00022483};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 1..136
FT /note="MHD2"
FT /evidence="ECO:0000259|PROSITE:PS51259"
FT DOMAIN 150..277
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
SQ SEQUENCE 322 AA; 36564 MW; EE704567A4B60A87 CRC64;
MDFLDKILSL SAKICEKTVL KRVLKELWKT VLNKIEKQIV LPPLTDQTGP QMIFSAAKDL
GQLSKLKDHV TREEARSLTL RQCAVMEIAL ATIKQYFHAG GNGLKKNYLE KSPALQSLKY
ALSLYTQTTD ALIKKFIATQ TSQSQSTNNA VGEIFVQVDV FTHPGTGEHR VTVKVIAINN
LNWQTTAMFR PFVEVCILGP NLSDKKRKHG TKTKSNTWSP KYNETFQFIL SNEEGLRSYE
LHLSVKDYCF AREDRIVGMT VIQLQHTAEK GSNTSWYPLL KNIYMDDTGL TILRILSQRT
NDEVAKEFVR LKSETRSVEE TA
//
