ID K7FTX4_PELSI Unreviewed; 384 AA.
AC K7FTX4;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Thioredoxin-interacting protein {ECO:0000256|ARBA:ARBA00039479};
GN Name=TXNIP {ECO:0000313|Ensembl:ENSPSIP00000011484.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000011484.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000011484.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the arrestin family.
CC {ECO:0000256|ARBA:ARBA00005298}.
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DR EMBL; AGCU01164002; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01164003; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006134740.1; XM_006134678.1.
DR AlphaFoldDB; K7FTX4; -.
DR STRING; 13735.ENSPSIP00000011484; -.
DR Ensembl; ENSPSIT00000011541.1; ENSPSIP00000011484.1; ENSPSIG00000010332.1.
DR GeneID; 102453782; -.
DR KEGG; pss:102453782; -.
DR CTD; 10628; -.
DR eggNOG; KOG3780; Eukaryota.
DR GeneTree; ENSGT00940000158522; -.
DR HOGENOM; CLU_039221_1_1_1; -.
DR OMA; GPQQCKQ; -.
DR OrthoDB; 22053at2759; -.
DR TreeFam; TF313650; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:Ensembl.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0071228; P:cellular response to tumor cell; IEA:Ensembl.
DR GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR GO; GO:0051782; P:negative regulation of cell division; IEA:Ensembl.
DR Gene3D; 2.60.40.640; -; 2.
DR InterPro; IPR014752; Arrestin-like_C.
DR InterPro; IPR011021; Arrestin-like_N.
DR InterPro; IPR011022; Arrestin_C-like.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR11188; ARRESTIN DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11188:SF14; THIOREDOXIN-INTERACTING PROTEIN; 1.
DR Pfam; PF02752; Arrestin_C; 1.
DR Pfam; PF00339; Arrestin_N; 1.
DR SMART; SM01017; Arrestin_C; 1.
DR SUPFAM; SSF81296; E set domains; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 167..294
FT /note="Arrestin C-terminal-like"
FT /evidence="ECO:0000259|SMART:SM01017"
SQ SEQUENCE 384 AA; 43023 MW; B5165507A025F38C CRC64;
MVVFKKIKTF ELVFSEPDKV YGSGEMEVAE VTRVSSVKVL ACGEAKVVWI KGPQQCKQEM
EYLRYEDVLT LDDQPTDEDC SVTLRPGNKY EYKFGFELPQ GPLGTSFKGK YGCVDYWVKA
FLDRPSCQTQ EIKKHFEVMD LVDVNTPDLM SPVAAKKEKK VSCMFIPDGH VSVSARIDRK
GFCEGDDICI NADFENTCSR IVVPKAAIVS KHTYLANGQT KVLTQKLSRV RGNHIISGMS
ESWRGKTLRV KKIKPSILGC NILRVEYFLQ IYVSVPGSKK IFLELPLVIG SRSGFASRSS
SMASQASSEM SWVDLNLPDA PEAPPCYLDI VPEDHRLESP TTPLLDDLDS SFDSPIFMYA
PEFKFMPPPT YTEVDPCNAN NNVQ
//
