ID K7FU26_PELSI Unreviewed; 1013 AA.
AC K7FU26;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 {ECO:0000313|Ensembl:ENSPSIP00000011536.1};
GN Name=SMARCA1 {ECO:0000313|Ensembl:ENSPSIP00000011536.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000011536.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000011536.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
CC {ECO:0000256|ARBA:ARBA00009687}.
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DR EMBL; AGCU01173165; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01173166; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01173167; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01173168; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01173169; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01173170; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01173171; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7FU26; -.
DR STRING; 13735.ENSPSIP00000011536; -.
DR Ensembl; ENSPSIT00000011593.1; ENSPSIP00000011536.1; ENSPSIG00000010101.1.
DR eggNOG; KOG0385; Eukaryota.
DR GeneTree; ENSGT00940000157297; -.
DR OMA; TAFYRKE; -.
DR TreeFam; TF300674; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0031491; F:nucleosome binding; IEA:InterPro.
DR CDD; cd18065; DEXHc_SMARCA1; 1.
DR CDD; cd00167; SANT; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR Gene3D; 1.20.5.1190; iswi atpase; 1.
DR Gene3D; 1.10.1040.30; ISWI, HAND domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR015194; ISWI_HAND-dom.
DR InterPro; IPR036306; ISWI_HAND-dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR InterPro; IPR015195; SLIDE.
DR InterPro; IPR044755; SMARCA1_N.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45623; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED; 1.
DR PANTHER; PTHR45623:SF49; SWI_SNF RELATED, MATRIX ASSOCIATED, ACTIN DEPENDENT REGULATOR OF CHROMATIN, SUBFAMILY A, MEMBER 1; 1.
DR Pfam; PF09110; HAND; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF09111; SLIDE; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF101224; HAND domain of the nucleosome remodeling ATPase ISWI; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51293; SANT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 138..303
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 433..596
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 798..850
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 79..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 761..791
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 974..1013
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 770..791
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 998..1013
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1013 AA; 118527 MW; 2285B737782C5559 CRC64;
QKNDPPFQLK LPPKASKPEK EIDPEYEEKM KTDRAKRFEF LLKQTELFAH FIQPAAQKSP
TSPLKVKLGR PRIKKDEKQS LLSAGDYRHR RTEQEEDEEL LSESRKTSNV CVRFEESPSY
VKGGTLRDYQ VRGLNWMISL YENGVNGILA DEMGLGKTLQ TIALLGYLKH YRNIPGPHMV
LVPKSTLHNW MNEFKRWVPS LRAVCLIGDK DARAAFIRDV MMPGEWDVCV TSYEMVIKEK
SVFKKFNWRY LVIDEAHRIK NEKSKLSEIV REFKTTNRLL LTGTPLQNNL HELWALLNFL
LPDVFNSADD FDSWFDTKNC LGDQKLVERL HAVLKPFLLR RIKAEVEKSL PPKKEVKIYL
GLSKMQREWY TRILMKDIDI LNSAGKMDKM RLLNILMQLR KCCNHPYLFD GAEPGPPYTT
DTHLVNNSGK MVALDKLLAK LKEQGSRVLV FSQMTRLLDI LEDYCMWRGY EYCRLDGQTP
HEEREDTCLQ FEILNNVEAI DTFNAPNSSK FIFMLSTRAG GLGINLATAD VVILYDSDWN
PQVDLQAMDR AHRIGQKKPV RVFRLITDNT VEDRIVERAE LKLRLDSIVI QQGRLIDQQS
NKLGKDEMLQ MIRHGATHVF ASKDSELTEE DITTILERGE KKTAEMNERL QKMGESSLRN
FTMDTEMSLY NFEGEDYREK QKLSMMEWIE PPKRERKANY AVDAYFREAL RVSEPKVPKA
PRPPKQPNIQ DFQFFPPRLF ELLEKEILYY RKTIGYKVPR NPDLPNAAQV QKEEQKKIDE
SAPHTPEETE EKEKLLTQGF TNWNKRDFNQ FIKANEKYGR DDIDNIAREV EGKSPEEVIE
YSAVFWERCN ELQDIERIMA QIERGEARIQ RRISIKKALD AKIARYKAPF HQLRIQYGTN
KGKNYTEEED RFLICMLHKM GFDKENVYEE LRQCVRNAPQ FRFDWFIKSR TAMEFQRRCN
TLISLIEKEN MEIEEKERAE KKKRGTKVPA SQKRKADSAT ENSGKKDAKK VKS
//
