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Database: UniProt
Entry: K7FUC0_PELSI
LinkDB: K7FUC0_PELSI
Original site: K7FUC0_PELSI 
ID   K7FUC0_PELSI            Unreviewed;       423 AA.
AC   K7FUC0;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   16-OCT-2019, entry version 43.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPSIP00000011630};
GN   Name=KCNJ6 {ECO:0000313|Ensembl:ENSPSIP00000011630};
OS   Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudines; Cryptodira; Trionychia; Trionychidae;
OC   Pelodiscus.
OX   NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000011630, ECO:0000313|Proteomes:UP000007267};
RN   [1] {ECO:0000313|Ensembl:ENSPSIP00000011630}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17381049; DOI=10.1080/10425170600760091;
RA   Jung S.-O., Lee Y.-M., Kartavtsev Y., Park I.-S., Kim D.S., Lee J.-S.;
RT   "The complete mitochondrial genome of the Korean soft-shelled turtle
RT   Pelodiscus sinensis (Testudines, Trionychidae).";
RL   DNA Seq. 17:471-483(2006).
RN   [2] {ECO:0000313|Proteomes:UP000007267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG   Soft-shell Turtle Genome Consortium;
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSPSIP00000011630}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; AGCU01106036; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01106037; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01106038; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01106039; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01106040; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01106041; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01106042; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01106043; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01106044; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01106045; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 13735.ENSPSIP00000011630; -.
DR   Ensembl; ENSPSIT00000011687; ENSPSIP00000011630; ENSPSIG00000010501.
DR   eggNOG; KOG3827; Eukaryota.
DR   eggNOG; ENOG410XQ62; LUCA.
DR   GeneTree; ENSGT00970000193368; -.
DR   OMA; NVGYNTG; -.
DR   TreeFam; TF313676; -.
DR   Proteomes; UP000007267; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015467; F:G-protein activated inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003275; K_chnl_inward-rec_Kir3.2.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF19; PTHR11767:SF19; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01328; KIR32CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007267};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     93    117       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    167    191       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       57    196       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      203    373       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      390    423       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    392    423       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   SITE        182    182       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   423 AA;  48599 MW;  0DD08AD0F4FAD0FC CRC64;
     QAYLFLHLSN VLEEDSMEQD VESPITIQQP KLPKQAREDL PKHISKVCTK RKIQRYVRKD
     GKCNVHHGNV RETYRYLSDI FTTLVDLKWR FNLLIFVMVY TVTWLFFGMI WWLIAYIRGD
     MEHIGDNTWT PCVSNLNGFV SAFLFSIETE TTIGYGYRVI TDKCPEGIIL LLVQSVLGSI
     VNAFMVGCMF VKISQPKKRA ETLVFSTNAV ISMRDGKLCL MFRVGDLRNS HIVEASIRAK
     LIKSKQTKEG EFIPLNQTDI NVGYYTGDDR LFLVSPLIIS HEINQQSPFW EISKDQLPKE
     ELEIVVILEG MVEATGMTCQ ARSSYVTSEI LWGHRFTPVL TLEDGFYEVD YNSFHETYET
     NTPSYSAKEL AEMASQAELP LTWSVSSKLN QHADLETEER EKNHEDQTER NGDVANLENE
     SKV
//
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