ID K7FUR9_PELSI Unreviewed; 894 AA.
AC K7FUR9;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Family with sequence similarity 171 member A1 {ECO:0000313|Ensembl:ENSPSIP00000011779.1};
GN Name=FAM171A1 {ECO:0000313|Ensembl:ENSPSIP00000011779.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000011779.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000011779.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the FAM171 family.
CC {ECO:0000256|ARBA:ARBA00006818}.
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DR EMBL; AGCU01060467; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01060468; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01060469; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01060470; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01060471; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01060472; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01060473; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01060474; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006119546.1; XM_006119484.2.
DR AlphaFoldDB; K7FUR9; -.
DR STRING; 13735.ENSPSIP00000011779; -.
DR Ensembl; ENSPSIT00000011836.1; ENSPSIP00000011779.1; ENSPSIG00000010577.1.
DR GeneID; 102462588; -.
DR KEGG; pss:102462588; -.
DR CTD; 221061; -.
DR eggNOG; ENOG502QR89; Eukaryota.
DR GeneTree; ENSGT00950000183184; -.
DR HOGENOM; CLU_019729_0_0_1; -.
DR OMA; PAECMMS; -.
DR OrthoDB; 4211644at2759; -.
DR TreeFam; TF331338; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR GO; GO:0043149; P:stress fiber assembly; IEA:Ensembl.
DR InterPro; IPR018890; FAM171.
DR InterPro; IPR049175; FAM171_C.
DR InterPro; IPR048530; FAM171_N.
DR PANTHER; PTHR31626:SF1; PROTEIN FAM171A1; 1.
DR PANTHER; PTHR31626; SUSHI DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF20771; FAM171A1-2-B_C; 1.
DR Pfam; PF10577; FAM171A1-2-B_N; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..894
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003902154"
FT TRANSMEM 303..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 33..286
FT /note="FAM171 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10577"
FT DOMAIN 396..892
FT /note="FAM171 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF20771"
FT REGION 632..651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 734..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 823..894
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 751..784
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 841..860
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 874..894
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 894 AA; 98647 MW; 1DB92F397F1A9E15 CRC64;
MSRSAALLLC LLGCNVWKAV TKTLGAPGAA REVTLKVHVS DASTHQPVTE AFIEIFTNQI
SIASGTSGAD GTAFITFQYQ LGNQLIVTAT KHAYVPNSAP WKPTRLPVFS SLSLGLLPER
SATLMVYDDV VQIVSGFQGA RVQPRVHFQR RALTLPENTS YSDLTAFLTA ASSPWEVDSF
PYLQGLDGNG TGNSTKHDLT PVTAVSVHLL NSDGTPIPVN GPIYVTVPLP TNSNLKHNGH
VPAWRFDQKF GTWLKSSLGL VQQEGNQLTW TYIAPQLGYW VAAMSPTNPG PTVIQDITSY
HTVFLLAILG GMALILVVLL CLLVYYCRRK CLKPRQHHKK LQLSTALDGS KKDQSTSMSH
INLIFSRRES EFPGGRSIAS NGHTENSGAK ELISAVHMEM VSSSGEADLH TPMLKHSYST
SQEFSSREEL LSHKEKDKIR ISLENLTPSG TLRKDYHKSV NTFASKSKNS IETSEGYESP
VKEDYRRSYN AMLSQPLFEK QEREIQASIN HISSGSKYNI QEQMYPSPSA PEKELLDCRP
AECMMSRSVD HLERPTSFPR PGQLICCNSV DQVNDSVYRK VLPTLVIPGH FMKLPGEHSY
ISQSLVAPAD QQIDIERLQA ELSNPHAQLF PHPQQQIQPQ QLSSQAISQQ HLQDAGASEW
SPQNASMSES ISIPASLNDA SLAQMNSEVQ LLTEKALMEL GGGKPLPHPR AWFVSLDGRS
NAHVRHSYID LQRAGRNGSN DASLDSGVDM NEPKSARRGR GDHLPLQHTH QPLKENHKKE
PKVSESTAYT QLVYLDDMDQ SGSECGTAVC SPEDSTLRSL LDGASRRSGV QLPSLQEETI
KRTAETADDP LTSPEHGTSV HDEDEDDDED DQGEDKKSPW QKREERPLMA FNIK
//
