ID   K7FW53_PELSI            Unreviewed;       512 AA.
AC   K7FW53;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=Nephrocan-like {ECO:0000313|Ensembl:ENSPSIP00000012263.1};
OS   Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC   Trionychidae; Pelodiscus.
OX   NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000012263.1, ECO:0000313|Proteomes:UP000007267};
RN   [1] {ECO:0000313|Proteomes:UP000007267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG   Soft-shell Turtle Genome Consortium;
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000007267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX   PubMed=23624526; DOI=10.1038/ng.2615;
RA   Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA   White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA   Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA   Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA   Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT   "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT   into the development and evolution of the turtle-specific body plan.";
RL   Nat. Genet. 45:701-706(2013).
RN   [3] {ECO:0000313|Ensembl:ENSPSIP00000012263.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AGCU01086838; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_006123120.1; XM_006123058.1.
DR   AlphaFoldDB; K7FW53; -.
DR   STRING; 13735.ENSPSIP00000012263; -.
DR   Ensembl; ENSPSIT00000012322.1; ENSPSIP00000012263.1; ENSPSIG00000011049.1.
DR   GeneID; 102445730; -.
DR   KEGG; pss:102445730; -.
DR   eggNOG; KOG0619; Eukaryota.
DR   GeneTree; ENSGT00940000162914; -.
DR   HOGENOM; CLU_000288_18_6_1; -.
DR   OMA; TCPRRCS; -.
DR   OrthoDB; 4636306at2759; -.
DR   TreeFam; TF336377; -.
DR   Proteomes; UP000007267; Unassembled WGS sequence.
DR   GO; GO:0005615; C:extracellular space; IEA:Ensembl.
DR   GO; GO:0005614; C:interstitial matrix; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 5.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR45712; AGAP008170-PA; 1.
DR   PANTHER; PTHR45712:SF1; NEPHROCAN; 1.
DR   Pfam; PF13855; LRR_8; 4.
DR   SMART; SM00364; LRR_BAC; 6.
DR   SMART; SM00365; LRR_SD22; 4.
DR   SMART; SM00369; LRR_TYP; 10.
DR   SUPFAM; SSF52058; L domain-like; 2.
DR   PROSITE; PS51450; LRR; 2.
PE   4: Predicted;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..512
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003902195"
SQ   SEQUENCE   512 AA;  58306 MW;  42FAC502DC6D2D57 CRC64;
     MHLYYVLIIL FPLYNSLSTL CPRRCNCDSM QSVQCYRVLQ VPREIPATTR RLYISHSKIK
     HLQITDFSKI SCLEELILSC SGTELVEDNT FKALSTLKSL ELWKNKLRRV PTFLPSSLEI
     LKLGGNSISV LHESDFEGLK KLRVLDIQNN LILAVSFSTL SPLCSLQSLT LDGNNIESVS
     GPLTLPRLKY LSMENNKLHS FSGSFFASLQ YLQFLRLTGN LLTKVPLNLP KSLLSLKLER
     NQLKVIRFRD MKHLENLSEL FLSENQLSSV DGAQLLPNLT TLELSRNHLQ TMPLRLPARL
     QKLDCSNNFI RRVTAQGFQD LRDLKHLFLD NNTVSMFEAG ALHGCAQLSN LALEQNLLIS
     IPLRLPDTLA RLDLKGNDIQ DVGERELKDL KQLQVLNLRN NKISALDRKV LEYLPRLRYL
     YLDGNPWNCT CDLLRTRRVL MAKGTDVKGG QCAAPAERQG ESWMSSKKIL QGCEDNLSSA
     EQSKEVKKKM KVDDLSNEGL KMDDDYYDYE ID
//