ID K7FWM1_PELSI Unreviewed; 741 AA.
AC K7FWM1;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Kelch like family member 5 {ECO:0000313|Ensembl:ENSPSIP00000012431.1};
GN Name=KLHL5 {ECO:0000313|Ensembl:ENSPSIP00000012431.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000012431.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000012431.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01130279; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01130280; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01130281; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01130282; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01130283; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01130284; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01130285; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01130286; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01130287; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01130288; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7FWM1; -.
DR STRING; 13735.ENSPSIP00000012431; -.
DR Ensembl; ENSPSIT00000012492.1; ENSPSIP00000012431.1; ENSPSIG00000011040.1.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000155358; -.
DR HOGENOM; CLU_004253_12_0_1; -.
DR OMA; TSSCHTM; -.
DR TreeFam; TF329218; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR CDD; cd18337; BTB_POZ_KLHL5; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR030606; KLHL5_BTB/POZ.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632:SF3; KELCH-LIKE PROTEIN DIABLO; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 6.
DR PRINTS; PR00501; KELCHREPEAT.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 2.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 206..273
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 80..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 136..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 741 AA; 82615 MW; E3FC1FC7C84185D2 CRC64;
TGRVCISLVL VGCTNPFLCA LLLACLDDHL LSLRMSGSRK EFDVKQILKI RWRWFSHQSS
TTNSTVNSHR GDFWNRGQNA TTGGTKFLDP GNPPLASIGY RKSNQQNFQN SPPWPMASSS
EVPTFEFTTE NCGDARWLDK PEADDGASEE ENESDSSSCR TSNSSPTLSS CQTMEPCTSD
EFFQALNHAE QTFKKMENYL RHKQLCDVIL VAGDRRIPAH RLVLSSVSDY FAAMFTNDVR
EARQEEIKME GVEPNALWAL VQYAYTGRLE LKEDNIECLL STACLLQLSQ VVEACCKFLM
KQLHPSNCLG IRSFADAQGC TDLHKVAHNF TMENFMEVIR NQEFLLLPAT EIAKLLASDD
MNIPNEETIL NALLTWVRHD LEQRRKDLSQ LLAYIRLPLL APQFLADMEN NALFKDDIEC
QKLIMEAMKY HLLPERRPML QSPRTKPRKS TVGVLFAVGG MDATKGATSI EKYELRTNMW
TPVANMNGRR LQFGVAVLDD KLYVVGGRDG LKTLNTVECY NPKTKTWSVM PPMSTHRHGL
GVAVLEGPMY AVGGHDGWSY LNTVERWDPQ ARQWNFVASM STPRSTVGVA VLNGKLYAVG
GRDGSSCLKS VECFDPHTNK WTLCAQMSKR RGGVGVTTWN GFLYAIGGHD APASNLTSRL
SDCVERYDPK TDVWTAVASM SISRDAVGVC LLGDKLYAVG GYDGQTYLNT VESYDPQTNE
WTQVAPLCLG RAGACVVTVK L
//
