ID K7FXF1_PELSI Unreviewed; 1714 AA.
AC K7FXF1;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Lymphocyte antigen 75 {ECO:0000313|Ensembl:ENSPSIP00000012711.1};
GN Name=LY75 {ECO:0000313|Ensembl:ENSPSIP00000012711.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000012711.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000012711.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01009998; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01009999; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01010000; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01010001; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01010002; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01010003; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01010004; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01010005; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01010006; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01010007; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSPSIT00000012772.1; ENSPSIP00000012711.1; ENSPSIG00000011279.1.
DR GeneTree; ENSGT01050000244842; -.
DR HOGENOM; CLU_002069_2_0_1; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd00037; CLECT; 10.
DR CDD; cd00062; FN2; 1.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 2.10.10.10; Fibronectin, type II, collagen-binding; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 10.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR018378; C-type_lectin_CS.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR000562; FN_type2_dom.
DR InterPro; IPR036943; FN_type2_sf.
DR InterPro; IPR013806; Kringle-like.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR22803:SF65; LYMPHOCYTE ANTIGEN 75; 1.
DR PANTHER; PTHR22803; MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED; 1.
DR Pfam; PF00040; fn2; 1.
DR Pfam; PF00059; Lectin_C; 10.
DR SMART; SM00034; CLECT; 10.
DR SMART; SM00059; FN2; 1.
DR SMART; SM00458; RICIN; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 10.
DR SUPFAM; SSF57440; Kringle-like; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS00615; C_TYPE_LECTIN_1; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 9.
DR PROSITE; PS00023; FN2_1; 1.
DR PROSITE; PS51092; FN2_2; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00479}; Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1661..1683
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 134..182
FT /note="Fibronectin type-II"
FT /evidence="ECO:0000259|PROSITE:PS51092"
FT DOMAIN 196..312
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 340..460
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 471..588
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 625..763
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 936..1058
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1088..1190
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1229..1339
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1381..1484
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1525..1651
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DISULFID 139..165
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00479"
FT DISULFID 153..180
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00479"
SQ SEQUENCE 1714 AA; 197861 MW; D7419887D57B3B4A CRC64;
TGNDAFTIRH EKTSKCLQIK DSWIVVADCK ETKETLWKWV SQNRLFHLGS QKCLGLNIAK
PELPLKMVNC DSQFMLWWRC VDASIYGASQ YKLILKDNFV TASINSSDTW RRSNSSEDIC
VYPYQEIYTK DGNSYGRPCE FPFLVNQTWH HDCILDDTHT GGEWCATTYD YIQDGKWGIC
LKPEDGCSDN WEHDPGSESC YQLNTQSALS WKEAYISCQT QGGDLLSITN TNELNYIQAK
DGIAEKFWIG LNQLDISGGW QWSDHTPLNF LNWNPDMQNI SPLDGSSCVA MNATSGQWQS
YYCETALPYV CKKPLNNTKS ELPDVWRYLE TQCDSGWLPY SGFCYMLMNN QASWNMADQS
CKANKSDLIS MHSLADVELI VTKLHNGKSE TKEEIWTGFM NVDTPALFKW SDGSKVVFTY
WDQNEPKIPF NSTPNCVSYS GKLGRWRVKS CEKKLKYVCM KKGEILNETI SDKHCFIKEG
WQRHGDFCYK IHNNKVSFGA QCNLTIMNRF EQEFINSLIG KYSKSEDKYF WTGLQDISRS
GKYTWGDVDG RKNAVMYANW NSLQPAFPGG CVAMSSGKFL GKWDVKDCKT FTALSICKNY
TGPPRQPEVL PKPTDPCPPG WKNGSGLACY KLSAHLSIQL FKRTWGEAER FCEALGGHLP
SFSDITEMKE LHSILRDIIS NDRWVWVGLN KRNPDSLGTW EWSDNNPETT VLLHDFTRDD
VRDCAALKKK QQLYLTAELY EDRQLDFYLK PFHCDARLEW VCQITKGITP KIPDWYTPDV
DGNHGPTFVV DEAEFWFVPD KHLSYQEAAF YCANNDSDLA SVDSYTKLRV LLNKIDQLAS
AEQKWWLKYL DYGVNYRPQI YSEMFLSSLQ LFPRFHDRFW RDCWYISSKS WYRDYPINCH
LKLPFICEKY NVSLLEKHEP EYHPPKGGCP KDWILFQNKC FLKIEHRFLK FKDANEKCET
LGGTLPSISS QAEQDFLTSL LPGLEQNIWI GLQFKFSTKE NQWVDGSRLL YSNFHPLLRG
RLRKVPLDLF DEDVNDQCGV MLNNPNSSYA GTWNFFPCVR EHFLGFCQKQ AGPADNQTQE
VLNETLTYQN VHYTLILKNV SWYDALQECK QKNMQLVSIT DQYQQAFLAV QAAIHNYPLW
IGLSSTDDGK HYTWADGKNV NFSRWSEEDD KTSEECVFLD VDGFWKTSEC FSENPGAICY
LPRNNTEKKQ IAEQIKCPHK FKNTPWISFQ NSCYTFMITK DRWQEMKSQE AHHLCKKINP
DAYVLNIRNE EENNFVVEQL YSFSGLATWV WLGVIYDDND NLLKWYDETP LFYNNWRQGR
PNVKKNQFFA GVNLDGFWDI YNRTLSWQAL QFNQHSILSC KIEMEIGSRE SKPPLPKSIS
HGNSTYRILQ KKITWYQALR ECKQNGSDLV SIHSESQQLF LEDIVKRDGY PLWLGLSSHG
GNESDLEWSD GSEFDYRPWE LENAVSSETC VVLDTKGFWK HARCTNVVEG AICYTTSDHR
RLQPQQTKGS SRCPQGTGTS QWLQYKDHCY AFDMALYNFS VYTAEEAERV CQKLEPSATL
LTIKDAEENT FVSRQIRQND LITRRVWLGL SQNEGCTGVD IQYLYLCGST VEYTNWANGT
AKVNGKCSVI LSTDGIWSEV DCSHSKGRVV CKAPLGTNHT GVAVAFALLI ILVLVAGLIW
YLYKKKRLQW GAFSAVHYER GINEDETDSM FTKD
//
