GenomeNet

Database: UniProt
Entry: K7G568_PELSI
LinkDB: K7G568_PELSI
Original site: K7G568_PELSI 
ID   K7G568_PELSI            Unreviewed;      2675 AA.
AC   K7G568;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   16-JAN-2019, entry version 40.
DE   SubName: Full=Inositol 1,4,5-trisphosphate receptor type 3 {ECO:0000313|Ensembl:ENSPSIP00000015429};
GN   Name=ITPR3 {ECO:0000313|Ensembl:ENSPSIP00000015429};
OS   Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudines; Cryptodira; Trionychia; Trionychidae;
OC   Pelodiscus.
OX   NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000015429, ECO:0000313|Proteomes:UP000007267};
RN   [1] {ECO:0000313|Ensembl:ENSPSIP00000015429}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17381049; DOI=10.1080/10425170600760091;
RA   Jung S.-O., Lee Y.-M., Kartavtsev Y., Park I.-S., Kim D.S., Lee J.-S.;
RT   "The complete mitochondrial genome of the Korean soft-shelled turtle
RT   Pelodiscus sinensis (Testudines, Trionychidae).";
RL   DNA Seq. 17:471-483(2006).
RN   [2] {ECO:0000313|Proteomes:UP000007267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG   Soft-shell Turtle Genome Consortium;
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSPSIP00000015429}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AGCU01059471; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01059472; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01059473; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01059474; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01059475; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01059476; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01059477; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01059478; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01059479; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01059480; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 13735.ENSPSIP00000015429; -.
DR   Ensembl; ENSPSIT00000015501; ENSPSIP00000015429; ENSPSIG00000013648.
DR   eggNOG; KOG3533; Eukaryota.
DR   eggNOG; ENOG410XR97; LUCA.
DR   GeneTree; ENSGT00940000157078; -.
DR   OMA; SFYNLMT; -.
DR   TreeFam; TF312815; -.
DR   Proteomes; UP000007267; Unassembled WGS sequence.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:Ensembl.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:Ensembl.
DR   GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0043235; C:receptor complex; IEA:Ensembl.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:Ensembl.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:Ensembl.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0050913; P:sensory perception of bitter taste; IEA:Ensembl.
DR   GO; GO:0050916; P:sensory perception of sweet taste; IEA:Ensembl.
DR   GO; GO:0050917; P:sensory perception of umami taste; IEA:Ensembl.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 4.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007267};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2218   2243       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2255   2273       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2285   2305       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2340   2366       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2386   2407       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2510   2533       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      114    174       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      175    225       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      233    289       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      296    373       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      379    435       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED       91    111       {ECO:0000256|SAM:Coils}.
FT   COILED     1589   1609       {ECO:0000256|SAM:Coils}.
FT   COILED     2620   2640       {ECO:0000256|SAM:Coils}.
FT   COILED     2648   2668       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2675 AA;  306103 MW;  F93892F406DC3189 CRC64;
     TMNEMSSFLH VGDIVSLYAE GSVNGFISTL GLVDDRCVVE PAAGDLDNPP KKFRDCLFKV
     CPMNRYSAQK QYWKAKQTKQ DKDKIADVVL LQKLQHAAQM EQKQNDTENK KVHGDVVKYG
     SVIQLLHMKS NKYLTVNKRL PALLEKNAMR VTLDATGNEG SWLFIQPFWK LRSAGDNVVV
     GDKVILNPVN AGQPLHASNY ELADNAGCKE VNSVNCNTSW KINLFMQFRD HMEEVLKGGD
     VVRLFHAEQE KFLTCDEYKA KLHVFLRTTL RQSATSATSS NALWEVEVVH HDPCRSGAGH
     WNGLYRFKHL ATGNYLAAEE NPSYKGDAAD PKSAPMGGAV RSSRRKTGEK IKYRLVAVPH
     GNDIASLFEL DPTTLQKTDS FVPRNSFVRL RHLCTNTWIQ STDVPIDIDE ERPIRLMLGT
     CPTKEDKEAF AIVSVPVSEI RDLDFANDAS SMLANVVEKM NEGFISQNDR RFVMQLLEDL
     VFFVSDVPNN GQNVLDIMVT KPNRERQKLM REQNILKQIF GILKAPFKDK GGEGPLVRLE
     ELSDQKNAPY QYMFRLCYRV LRHSQEDYRK NQEHIAKQFG MMQSQIGYDI LAEDTITALL
     HNNRKLLEKH ITKTEVETFV SLVRKNREPR FLDYLSDLCV SNHIAIPVTQ ELICKCVLDP
     KNSDILIKTE LRPVKEMSQT HEYLSIEYSE EEVWLTWSDK NNEPHEKSIR QLAQEARAGN
     AHDENVLSYY RYQLKLFARM CLDRQYLAIK EISKQLGVDL IFLCMADEML PFDLRASFCH
     LMLHVHVDRD PQELVMPVKF ARLWTEIPTA ITIKDYDSNL NDSRDDKKNK FASTMEFVED
     YLNNVVSEAV PFANDEKNKL TFEVVSLAHN LIYFGFYSFS ELLRLTRTLL GIIDCVQNPQ
     LMMQMPYSED MAGKNVRKSI QGVGQMMSTM VLSRKQSIFS PPSHSTVVAS ESTDRERTID
     NENIVVMETK LKILEILQFI LNVRLDYRIS YLLSVFKKEF IEVYPMQDSG ADGTAPAFDS
     TNAAMNLEKI GEQAEAMFGV GKSSSMLEVD DEGGRMFLRV LIHLTMHDYP PLVSGSLQLL
     FKHFSQRQEM LHTFKQVQLL ISAQDVENYK VIKSELDKLR TMVEKSELWV DKKGSTKGED
     AGEGAKKEKK EQPHEETSIT EEKSSENYQI VKGILERLNK MCGVGEQVRR KQQRLMKNMD
     AHKVMLDLLQ IPYEKGDAKM LEILKYTHQF LQKFCAGNQG NQALLHKHLN LFLTPGLLEA
     ETMQHIFLNN YQLCSEISET VLQHFVHCLA THGRHVQYLD FLHSIIKAEG KYVKKCQDMI
     MTELTNAGDD VVVFYNDKAS LATMLEMMTA AREGVEENSP LMYHISLVDL LAACAEGKNV
     YTEIKCTSLL PLEDIVRVVT HEDCITEVKM AYVNFVNHCY VDTEVEMKEI YTSNHIWTLF
     ENFILDMATM CKKREKRLTD PALEKYVLTV VLDTINAFFS SPFSENSTSL QMCKKREKRL
     TDPALEKYXC SWLQQQHKRA VEACIRTLAM VGAGGTGQAG GVDDALCAER RHSGAQPHGP
     HAHRAWRRSA SSYKATTRTF PRVSAMPNQW DYKNIIEKLQ EIINALEERF KPLVEAELSV
     LVDVLHRPEL LFMEGTDAYQ RCESGGFLSK LVQHTKDLME SEEKLCIRVL RTLQQMLMKK
     NKYGERGNEL RKTLLGNYLQ NKKSSSKGSG MPLGLSSPCV MMGDSSGTGQ DQDWSVIAAI
     QCRLDREGAT KLVSDLIMNT KNEKIFQESI LLAIRLLDGG NTEIQKSFYN LMMSDRKCEK
     FFKVLHDRMK KAQQETKSTV SVNMSDIGNK PQEDKDAPDP GTKGKWEGRV RVSGQPLLSS
     QLGMCLSPLS AFSLRRGTLM LSHPPSRHPI ALGFRKGHDA GERSQNNEMG LSVLIMEPIL
     RFLQLLCENH NRDLQNFLRC QNNKTNYNLV CETLQFLDIM CGSTTGGLGL LGLYINEYNV
     ALITQTLETL TEYCQGPCHE NQSCIVTHES NGIDIITALI LNEISPLCKY RMDLVLQLKD
     NASKLLLALM ESRHDSETAE RILISLRPQQ LVDVIKKAYL EEEECENSEV SPREVGHNIY
     ILALQLSLHN KQLTQMLKST APVQEEEEDP LAYYERHTSQ IEIVRLDRSM EQIIFPVPNI
     CEFLTRETKY RLFTTTEQDD QGSKVSDFFD QSSFLHNEME WQKKLRSMPL MYWFSRRMTL
     WGSISFNLAV FINIIIAFFY PYVEATSMGV LDSPLISLLF WFLICFSVMA MFTRRYGIRP
     LLVALILRSI YYLGIGLTLN ILGALNLTNK IVFVVSFVGN RGTFIRGYKA MIMDMEFLYH
     VAYIVTSILG LFVHELFYSI LLFDLIYREE TLFNVIKSVT RNGRSILLTA LLALILVYLF
     SIVGFLFLKD DFIMEVDRLP DNKSKGLYTC SAMQLWVVVQ WVVQGLGSPS DPNVCKNDDE
     DKSERACDTL LMCIVTVLNH GLRNGGGVGD ILRKPSKDES LFPARVIYDL LFFFIVIIIV
     LNLIFGVIID TFADLRSEKQ KKEEVLKTTC FICGLERDKF DNKTVSFEEH IKYEHNMWNY
     LYFIVLVRVK NKTDYTGPES YVAQMIKNKN LDWFPRMRAM SLVSNEGEGE QNEIRNLQEK
     LNSTMKLVSY LTSQLNELKE QMTEQRKRRQ RLGFV
//
DBGET integrated database retrieval system