ID K7G6I7_PELSI Unreviewed; 436 AA.
AC K7G6I7;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=55 kDa erythrocyte membrane protein {ECO:0000256|ARBA:ARBA00020455};
DE AltName: Full=Membrane protein, palmitoylated 1 {ECO:0000256|ARBA:ARBA00031599};
GN Name=MPP1 {ECO:0000313|Ensembl:ENSPSIP00000015898.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000015898.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000015898.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MAGUK family.
CC {ECO:0000256|ARBA:ARBA00007014}.
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DR EMBL; AGCU01008222; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01008223; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01008224; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01008225; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01008226; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01008227; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01008228; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01008229; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01008230; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7G6I7; -.
DR STRING; 13735.ENSPSIP00000015898; -.
DR Ensembl; ENSPSIT00000015973.1; ENSPSIP00000015898.1; ENSPSIG00000014074.1.
DR eggNOG; KOG0609; Eukaryota.
DR GeneTree; ENSGT00940000158744; -.
DR HOGENOM; CLU_001715_5_1_1; -.
DR OMA; KETQGMV; -.
DR TreeFam; TF314263; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0034451; C:centriolar satellite; IEA:Ensembl.
DR GO; GO:0030863; C:cortical cytoskeleton; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0090022; P:regulation of neutrophil chemotaxis; IEA:Ensembl.
DR CDD; cd00071; GMPK; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd12080; SH3_MPP1; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR020590; Guanylate_kinase_CS.
DR InterPro; IPR035475; MPP1_SH3.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23122:SF37; 55 KDA ERYTHROCYTE MEMBRANE PROTEIN; 1.
DR PANTHER; PTHR23122; MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 41..122
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 128..198
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 252..421
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
SQ SEQUENCE 436 AA; 48867 MW; 0230D53EE67DBFF1 CRC64;
LPRQAVAYPS NAVTEDIYTN GSAMPGTPAA GNAREVRKIR LVQFERVTEE PMGITLKLNE
KQSCMVARIL HGGMIHRQGS LHVGDEIIEI NGQSASNHSV EQLQKMLREA KGTVSIKVIP
NQQSRLPALQ MFMRAQFDYD PKADSLIPCK EAGLKFKTGD IIQIINKDDS NWWQGRVEGS
SLESAGLIPS PELQEWLVAR ESQAGQREAQ SCSPFGKKKK CKDKYLAKHS SIFDQLDVVS
YEEVVRLPAF KRRTLVLIGA SGVGRSHIKN ALLSKSPERF GYPAPYTTRP MRKSEAPGQD
YHFVSTEEMT RDIAANAFLE FGSYQGNIFG TKFETVHQIH QLEKVAILDI EPQTLKIVRT
AELAPFIVFI APPDQADQSE ALQQLHKESE SIRSRYAHYF DLALVNNGVE ESLKLLQEAW
DQACSSPQWV PVSWVY
//
