ID K7GAY1_PELSI Unreviewed; 541 AA.
AC K7GAY1;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Activated leukocyte cell adhesion molecule {ECO:0000313|Ensembl:ENSPSIP00000017442.1};
GN Name=ALCAM {ECO:0000313|Ensembl:ENSPSIP00000017442.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000017442.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000017442.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC Cell projection, axon {ECO:0000256|ARBA:ARBA00004489}. Cell projection,
CC dendrite {ECO:0000256|ARBA:ARBA00004279}.
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DR EMBL; AGCU01044348; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01044349; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01044350; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7GAY1; -.
DR Ensembl; ENSPSIT00000017521.1; ENSPSIP00000017442.1; ENSPSIG00000015483.1.
DR eggNOG; ENOG502RMQM; Eukaryota.
DR GeneTree; ENSGT00940000156881; -.
DR HOGENOM; CLU_028888_2_0_1; -.
DR OMA; SLNVSAX; -.
DR TreeFam; TF321859; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0030424; C:axon; IEA:UniProtKB-SubCell.
DR GO; GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.
DR GO; GO:0009897; C:external side of plasma membrane; IEA:Ensembl.
DR GO; GO:0001772; C:immunological synapse; IEA:Ensembl.
DR GO; GO:0043025; C:neuronal cell body; IEA:Ensembl.
DR GO; GO:0042101; C:T cell receptor complex; IEA:Ensembl.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0007157; P:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; IEA:Ensembl.
DR GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR CDD; cd00096; Ig; 2.
DR CDD; cd00098; IgC1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR PANTHER; PTHR11973:SF2; CD166 ANTIGEN; 1.
DR PANTHER; PTHR11973; CELL SURFACE GLYCOPROTEIN MUC18-RELATED; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 486..508
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 85..194
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 205..287
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 306..368
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 375..454
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 520..541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 541 AA; 60625 MW; C0AD8AD6374CFDF0 CRC64;
MPCPQEVPSE LMFGKWKFET ANDSPVFIAF RSSTKKSVQY DDVPEYKDRL SLSENYTLSI
KNARISDEKR FVCMLVTEDN VFEEPTVVKV FKQPSQPEII HPANFLETGK LKMLGECIAR
ESYPEGNITW YKNGNILQPI EGVVVMSLQK TVDKSNGLFT TTSSLQYMPT KKDANAQFAC
SVTYYGPSGQ DTIPSQPVIF DVRYPTEKVT IKVLSQRNTI KEGDNITLKC SGNGNPPPQE
FLFYIPGELE AIRGSETYVM TDVRRNATGQ YKCSLMDRSM EDSTSITVHY LDLSLTPSGE
VTKQIGEALP VSCTISSSRN ATVFWMKDNT RMPTSPSFSS LKYQDAGNYI CETNLLEVEG
LKKRKTLKLI VEGKPQIKMT KKTESNKSKT IVCHVEGFPK PAVQWTITGS GSIINKTEES
KYVNGRFSSK IVISPEENVT LTCTAENQLE RTVTSMNVSA ISIPEYDEPD ERNGDNREKV
NDQAKLIVGI VVGLLLVALV AGIIYWVYMK RSKTASKHVN KDLGNTEENK KLEENNHKSE
P
//
