ID K7GBB9_PELSI Unreviewed; 1721 AA.
AC K7GBB9;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Kinesin family member 13B {ECO:0000313|Ensembl:ENSPSIP00000017580.1};
GN Name=KIF13B {ECO:0000313|Ensembl:ENSPSIP00000017580.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000017580.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000017580.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR EMBL; AGCU01169195; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01169196; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01169197; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01169198; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01169199; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01169200; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01169201; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01169202; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSPSIT00000017659.1; ENSPSIP00000017580.1; ENSPSIG00000015490.1.
DR GeneTree; ENSGT00940000155500; -.
DR HOGENOM; CLU_001485_29_2_1; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd22730; FHA_KIF13B; 1.
DR CDD; cd01365; KISc_KIF1A_KIF1B; 1.
DR CDD; cd22265; UDM1_RNF168; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.250.2520; -; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR InterPro; IPR032405; Kinesin_assoc.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF5; -; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF12473; DUF3694; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF12423; KIF1B; 1.
DR Pfam; PF00225; Kinesin; 1.
DR Pfam; PF16183; Kinesin_assoc; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM01052; CAP_GLY; 1.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 1..309
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT DOMAIN 1622..1664
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 506..537
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1334..1357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1554..1595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1701..1721
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 567..599
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 517..537
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1334..1355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 59..66
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1721 AA; 191676 MW; 76D85E0EFF7C5660 CRC64;
SSGNCRSQPK VFAYDHCFWS MDESVKEKYA GQDVVFMCLG ENILQNAFEG YNACIFAYGQ
TGSGKSYTMM GTADQPGLIP KLCSGLFERA QKEENEEQSF KVEVSYMEIY NEKVRDLLDP
KGSRQSLKVR EHNVFGPYVD GLSKLAVASY KDIESLMSEG NKSRTVAATN MNEESSRSHA
VFKIILTHTL CDVQSGTSGE KVGKLSLVDL AGSERATKTG AAGDRLKEGS NINKSLTTLG
LVISALADQA AGKNKNKFVP YRDSVLTWLL KDSLGGNSKT AMVATVSPAA DNYDETLSTL
RYADRAKNIV NHAVVNEDPN ARIIRELREE VEKLREQLTK AEALKSPELK EQLVESEKLI
QEMTVTWEEK LRKTEEIAQE RQKQLESLGI SLQSSGIKVG DNKCFLVNLN ADPALNELLV
YYLKEHTLIG SDDSQDIQLC GMGILPEHCI IEITSEGQVM LTPKQNTRTC VNGSTVMGPT
QLHHGDRILW GNNHFFRLSL PKKKKKVEHE EEEQDNTMGC SNSVEQLDAD GDNSSEVSSE
MNFSYEYAQM EVTMKALSSN DPMQSILHSL EEKHEEEKRS ALEQQRLMYE HELEQLRRRL
SPEKQHLRSM DRFPFHSPNA QQRLRQWAEE REEMLNHSLR KLREQIVKAN LFVREASFIA
EEMDKKTEYK VTLQIPASSL NANRKRGAAL SEPAIQVRRK GKGKQIWSLE KLENRLIDMR
DLYQEWKNCN EDSPVSRSYF KRADPFYDEQ ENHSLIGVAN VFLESLFYDV KLQYAVPIIN
QKGEVSGRLH VEVVRVSGAI GERIVGGDDS TDSSRENDIQ ENKVVCMIKI LQATGLPQHL
SNFVFCKYTF WDQLDPVTVA PEMDPSLSPI SKEPQCMVVF DHCNEFSVNI SEDFMEHLYE
GALAIEVYGH KQSDPRKNSA LWDLGIIQAK TRSLRDRWSE VTRKVELWLQ ILELNENGEF
YPVEVVPAKD VNTGGIFQLR QGQSRRIQVE VKTVQESGTL PLMEESILSV GVGCVQIRHI
KSQKARGGAQ FHDEVDDMDS YQDRDLERLR RKWLSVLTKR QEYLDQQLQK LVSKPDKTED
DADREAQLLE MRLTLTEERN AVMVPSAGSG IPGAPAEWTP VPGMETHIPV VFLDLNADDF
SSQDNLDDPE PGGWDATLTG EEEDEFFELQ IVKHHESEVK VEASWDSTVH NCIQLSKGTA
TDERVFLIVR VTVQLSHPAE MQLVLRKRIC VNVYGKQSFA QSFLKRMSHR SSIPGCGVTC
EIVSNIPEVD TQGAEEREAL ARMAANAENA ASADSEAYIE KYLRSVLAVE NILTLDRIRQ
EVAVKEQLTG KGKLNRRSLS SPNVNRTSGS RQDLAPVYSL GSHKPVPRIM VQSASIDASA
AKIKQAYKGP SPRAQILTIL GQARNCIKLC DRVFLCNGGN ALIIPSDIQA QDSQEGPPSP
LSEASSGYFS HSVSTATLSD ALAAGNDLIA PTGGQTATTS HISPPTSAVP VPSDISVPMD
RASEGCPALL KSRASKPQLP PDLSSQPSAT VSPFKIQKVR TSELKSFTCM LGGESGCSSN
TEEEKEREKT AQGLSQNGAN TADEKLEVTS DSEDANEIPD WLKEGEYVTV GPNKTGTIRY
IGPTDFQEGM WVGVELDLPS GKNDGSIGGR QYFKCNPGYG LLVKPNRVKK APGVARRRST
GLKLQPASHL ASLTALAKME GSALRPEKIQ KSAENRKSWA N
//
