GenomeNet

Database: UniProt
Entry: K7GD67_PELSI
LinkDB: K7GD67_PELSI
Original site: K7GD67_PELSI 
ID   K7GD67_PELSI            Unreviewed;      1507 AA.
AC   K7GD67;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   11-DEC-2019, entry version 52.
DE   SubName: Full=Rho GTPase activating protein 5 {ECO:0000313|Ensembl:ENSPSIP00000018228};
GN   Name=ARHGAP5 {ECO:0000313|Ensembl:ENSPSIP00000018228};
OS   Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudines; Cryptodira; Trionychia; Trionychidae;
OC   Pelodiscus.
OX   NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000018228, ECO:0000313|Proteomes:UP000007267};
RN   [1] {ECO:0000313|Ensembl:ENSPSIP00000018228}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17381049; DOI=10.1080/10425170600760091;
RA   Jung S.-O., Lee Y.-M., Kartavtsev Y., Park I.-S., Kim D.S., Lee J.-S.;
RT   "The complete mitochondrial genome of the Korean soft-shelled turtle
RT   Pelodiscus sinensis (Testudines, Trionychidae).";
RL   DNA Seq. 17:471-483(2006).
RN   [2] {ECO:0000313|Proteomes:UP000007267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG   Soft-shell Turtle Genome Consortium;
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSPSIP00000018228}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2012) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AGCU01049646; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01049647; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AGCU01049648; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_006117720.1; XM_006117658.2.
DR   STRING; 13735.ENSPSIP00000018228; -.
DR   Ensembl; ENSPSIT00000018313; ENSPSIP00000018228; ENSPSIG00000016183.
DR   GeneID; 102452056; -.
DR   KEGG; pss:102452056; -.
DR   CTD; 394; -.
DR   eggNOG; KOG4271; Eukaryota.
DR   eggNOG; ENOG410XR4E; LUCA.
DR   GeneTree; ENSGT00940000154553; -.
DR   KO; K13709; -.
DR   OMA; HIDKVND; -.
DR   OrthoDB; 110157at2759; -.
DR   TreeFam; TF324451; -.
DR   Proteomes; UP000007267; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0042169; F:SH2 domain binding; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.10.440; -; 3.
DR   Gene3D; 1.10.555.10; -; 1.
DR   InterPro; IPR002713; FF_domain.
DR   InterPro; IPR036517; FF_domain_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR039007; pG1.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR032835; RhoGAP-FF1.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   InterPro; IPR039006; RhoGAP_pG2.
DR   InterPro; IPR001806; Small_GTPase.
DR   Pfam; PF01846; FF; 1.
DR   Pfam; PF00071; Ras; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   Pfam; PF16512; RhoGAP-FF1; 1.
DR   SMART; SM00441; FF; 4.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; SSF48350; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF81698; SSF81698; 1.
DR   PROSITE; PS51676; FF; 4.
DR   PROSITE; PS51852; PG1; 1.
DR   PROSITE; PS51853; PG2; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT   DOMAIN          267..325
FT                   /note="FF"
FT                   /evidence="ECO:0000259|PROSITE:PS51676"
FT   DOMAIN          367..420
FT                   /note="FF"
FT                   /evidence="ECO:0000259|PROSITE:PS51676"
FT   DOMAIN          427..481
FT                   /note="FF"
FT                   /evidence="ECO:0000259|PROSITE:PS51676"
FT   DOMAIN          482..548
FT                   /note="FF"
FT                   /evidence="ECO:0000259|PROSITE:PS51676"
FT   DOMAIN          590..763
FT                   /note="PG1 pseudoGTPase"
FT                   /evidence="ECO:0000259|PROSITE:PS51852"
FT   DOMAIN          779..944
FT                   /note="PG2 pseudoGTPase"
FT                   /evidence="ECO:0000259|PROSITE:PS51853"
FT   DOMAIN          1266..1453
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          981..1004
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1025..1052
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1065..1093
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1134..1160
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1172..1259
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1026..1040
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1077..1093
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1172..1203
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1236..1252
FT                   /note="Basic"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1507 AA;  172741 MW;  D3D5E5FBDDEAB7B4 CRC64;
     MMAKNKEPRP PSYAISVVGL SGTEKDKGNC GVGKSCLCNR FVRSKADEYY PEHTSVLSTI
     DFGGRVVNND HFLYWGDITQ SGEEGIECKI HVIEQTEFID DQTFLPHRST NLQPYIKRAA
     ASKLQSAEKL MYICTDQLGL EQDFEQKQMP EGKLNIDGFL LCIDVSQGCN RKFDDQLKFV
     NNLYVQLSKS KKPIIIAATK CDECVDHYLR EVQAFASNKK NLVVVETSAR FNINVETCFT
     ALVQMMDKTR GKPKIIPYLD AYKTQRQLVV TATDKFEKLV QTVRDYHATW KSVSNKLKNH
     PDYEEYINLE GTKKAKNTFS KHTEQLKQEH IRKRREEYIN TLPRAFNTLL SNLDEIEHLN
     WSEALKIMEK RPDFQLCFVV LEKTPWDETD QIDKVNDRRI PFDLLSTLEA EKVYQNHVQH
     LISEKRRVEM KEKFKKTLEK IQFISPGQPW EEVMCFVMED EAFKYITDAD SKEVYSRHQR
     EIVEKAKEEF QEMLFEHSEL FYDLDLNATP SSDKMSEIHA VLSEEPRYKA LQKLAPDRES
     LLLKHIGFVY HPTKETCLSG QNCTDMKVEQ LLANSLLQLD HGRQNLYHDS ANIDKINLFI
     LGKDGLAQEL ANEIRTQSTD DEYALDGKIY ELDLRPVDAK SPYLLSQLWT SAFKPHGFFC
     VFNSIESLNF IGECIGKIRV EASQIRRDKY MANLPFTLIL ANQRDSISKN LPILRHQGQQ
     LANKLQCPFV DVPAGTYPRK FNETQIKQAL RGVLEAVKRN LDVVSPVPTI KDLSEADLRI
     VMCAMCGDPF SVDLILSPFL DSHSCSAAQA GQNNTLMLDK IIGEKRRRIQ ITILSYHSSI
     GVRKDELVHG YILVYSAKRK ASMGMLRAFL SEVQDTIPVQ LVAVTDSQAD FFENEAIKEL
     MTEGEHIATE ITAKFTALYS LSQYHRQTEV FTLFFSDVLE KKNMIENSYM SDSTRESTHT
     SEDVFLQSPR GNSLAYNYYP DSEDDTEAPP PYSPIGDDVQ LLPTPSDRSK YRLDLEGNEY
     PVHSTPLNCH DHERNHKVPP PIKPKPLVPK TNVKKLDPNL VKTIEAGIGK NPKKQSSRVP
     LAPTEDSDQS DNYAEPIDTV FKHRGFTDDI YAVPDDSQNR IIKIRNSFVI NNAQGDEENG
     FSDRISKSHG ERRPSKYKYK SKTLFSKAKS YYRRTHSDAS DDEAFTTSKT KRKGRHRGSE
     EDPLLSPVET WKGGIDNPAI TSDQELDDKK MKKKTQKVKE DKKQKKKTKT FNPPTRRNWE
     SNYFGMPLQD LVTPEKPIPL FVEKCVEFIE DTGLCTEGLY RVSGNKTDQD NIQKQFDQDH
     NINLESMEVT VNAVAGALKA FFADLPDPLI PYSLHPELVE ASKILEKTER MHELKEIVKK
     FHPVNYDVFK FIITHLNRVS QQNRTNLMTA DNLSICFWPT LMRPDFENRE FLSTTKIHQS
     VIETFIQQCQ FFFYNGEIVE TSNTAACQPP TSNAVQMVEP MVPLQLPPPL QPQLIQPQLQ
     ADPLGII
//
DBGET integrated database retrieval system