ID K7GGC8_PELSI Unreviewed; 538 AA.
AC K7GGC8;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=SRCR domain-containing protein {ECO:0000259|PROSITE:PS50287};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000019339.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000019339.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR EMBL; AGCU01001475; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01001476; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01001477; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7GGC8; -.
DR Ensembl; ENSPSIT00000019429.1; ENSPSIP00000019339.1; ENSPSIG00000017166.1.
DR eggNOG; ENOG502QQ5W; Eukaryota.
DR GeneTree; ENSGT00940000164042; -.
DR HOGENOM; CLU_002555_11_3_1; -.
DR OMA; AKDQCAG; -.
DR TreeFam; TF329295; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.10.250.10; SRCR-like domain; 4.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR19331:SF22; DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN; 1.
DR PANTHER; PTHR19331; SCAVENGER RECEPTOR DOMAIN-CONTAINING; 1.
DR Pfam; PF00530; SRCR; 4.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 4.
DR SUPFAM; SSF56487; SRCR-like; 4.
DR PROSITE; PS00420; SRCR_1; 2.
DR PROSITE; PS50287; SRCR_2; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 481..504
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..99
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 130..230
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 235..335
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 356..456
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DISULFID 37..98
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 68..78
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 155..219
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 168..229
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 199..209
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 259..323
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 303..313
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 381..445
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 394..455
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 425..435
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 538 AA; 58264 MW; 4ABB909AAF415D68 CRC64;
LLSGESRCDG RVEISLRGVW SRVLDDQWDM NDASVVCRQL QCGAAERAYN PPSSERGMGP
VGMRRVQCAG NETHLIGCDN STSELAQARI AEDIGVVCSG ESFPDLTHVL WAAGRQALTA
GICPTGSRRI RLVNGPGRCA GRVEIYYNGT WGTVCDDSWD LPDADVVCKQ LGCGHALNAT
VSAHYGQGSG QIWLDDVKCS GNESDLWACP FAPWGQHNCR HKEDAGVLCS EFTDLRLVNS
RDCAGRLEVF YNGTWGSVCS NQMSGVTPSI VCKQLDCGDK RNIESGPEYG EGSGPTWLDH
VTCREQHSSL WQCPSRPWEQ QSCDNRAEET HITCPGTSTS TPSSPSPWGC RGRDKLRLVG
GESNCSGRVE VWYRGSWGTV CDDSWDLADA NVACKQLGCG AAVSAPGEAA FGEGTGPIWV
EMLNCRGTEL SLWDCRAKPW GDSNCGHKED AAVSCSGVAQ RMDSVNIPAP PRHPATDSGR
FMVPVVVCII LGALLCLVLI ILGVQVQSAR AQRRGSRRSS DPFSEAVYEE IDYDLMRK
//
