ID K7GRY9_PIG Unreviewed; 198 AA.
AC K7GRY9;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Interleukin 17D {ECO:0000313|Ensembl:ENSSSCP00000030669.3};
GN Name=IL17D {ECO:0000313|Ensembl:ENSSSCP00000030669.3};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000030669.3, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000030669.3, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000030669.3,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000030669.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the IL-17 family.
CC {ECO:0000256|ARBA:ARBA00007236}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; K7GRY9; -.
DR SMR; K7GRY9; -.
DR STRING; 9823.ENSSSCP00000030669; -.
DR PaxDb; 9823-ENSSSCP00000023910; -.
DR Ensembl; ENSSSCT00000035652.4; ENSSSCP00000030669.3; ENSSSCG00000025308.5.
DR eggNOG; ENOG502RXIG; Eukaryota.
DR GeneTree; ENSGT00940000161739; -.
DR InParanoid; K7GRY9; -.
DR OrthoDB; 4208634at2759; -.
DR Proteomes; UP000008227; Chromosome 11.
DR Bgee; ENSSSCG00000025308; Expressed in endocardial endothelium and 42 other cell types or tissues.
DR ExpressionAtlas; K7GRY9; baseline and differential.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR GO; GO:1903707; P:negative regulation of hemopoiesis; IEA:Ensembl.
DR GO; GO:1900017; P:positive regulation of cytokine production involved in inflammatory response; IEA:Ensembl.
DR GO; GO:0032725; P:positive regulation of granulocyte macrophage colony-stimulating factor production; IEA:Ensembl.
DR GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR GO; GO:0032757; P:positive regulation of interleukin-8 production; IEA:Ensembl.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR020440; IL-17_chr.
DR InterPro; IPR010345; IL-17_fam.
DR Pfam; PF06083; IL17; 1.
DR PRINTS; PR01932; INTRLEUKIN17.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
PE 3: Inferred from homology;
KW Cytokine {ECO:0000256|ARBA:ARBA00022514};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..198
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5023943828"
FT REGION 72..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 198 AA; 21087 MW; BBCC02991DFFE741 CRC64;
MLGPPVWALV AGVLLALSPG RAGGAPRAGR RPARARGCAD RPEELLEQLY GRLAAGVLGA
FHHTLQLGPR EQARNASCPA GGRPADRRFR PPTNLRSVSP WAYRISYDPG RFPKYLPEAY
CLCRGCLTGP AGAEDLRLRS APVLVPAVVL RRTPACAGGR AVYTEEYVTV PVGCTCVPQQ
QQQEAGGVPS GLDKQARP
//
