GenomeNet

Database: UniProt
Entry: K7HB22_CAEJA
LinkDB: K7HB22_CAEJA
Original site: K7HB22_CAEJA 
ID   K7HB22_CAEJA            Unreviewed;      6545 AA.
AC   K7HB22;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   31-JUL-2019, entry version 46.
DE   RecName: Full=Toprim domain-containing protein {ECO:0000259|PROSITE:PS50880};
OS   Caenorhabditis japonica.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=281687 {ECO:0000313|EnsemblMetazoa:CJA21342c, ECO:0000313|Proteomes:UP000005237};
RN   [1] {ECO:0000313|EnsemblMetazoa:CJA21342c}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DF5081 {ECO:0000313|EnsemblMetazoa:CJA21342c};
RG   Caenorhabditis japonica Sequencing Consortium;
RA   Wilson R.K.;
RL   Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CJA21342c}
RP   IDENTIFICATION.
RC   STRAIN=DF5081 {ECO:0000313|EnsemblMetazoa:CJA21342c};
RG   EnsemblMetazoa;
RL   Submitted (NOV-2012) to UniProtKB.
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DR   STRING; 281687.CJA21342c; -.
DR   EnsemblMetazoa; CJA21342c; CJA21342c; WBGene00176914.
DR   eggNOG; ENOG410IV4Q; Eukaryota.
DR   eggNOG; KOG1956; Eukaryota.
DR   eggNOG; COG0550; LUCA.
DR   eggNOG; COG0630; LUCA.
DR   eggNOG; COG3451; LUCA.
DR   eggNOG; COG3504; LUCA.
DR   eggNOG; COG3505; LUCA.
DR   eggNOG; COG3704; LUCA.
DR   eggNOG; COG3736; LUCA.
DR   Proteomes; UP000005237; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019867; C:outer membrane; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003917; F:DNA topoisomerase type I activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   GO; GO:0009405; P:pathogenesis; IEA:InterPro.
DR   GO; GO:0030255; P:protein secretion by the type IV secretion system; IEA:InterPro.
DR   CDD; cd00186; TOP1Ac; 1.
DR   CDD; cd03363; TOPRIM_TopoIA_TopoI; 1.
DR   CDD; cd06911; VirB9_CagX_TrbG; 1.
DR   Gene3D; 1.10.290.10; -; 1.
DR   Gene3D; 1.10.460.10; -; 1.
DR   Gene3D; 1.20.58.430; -; 1.
DR   Gene3D; 2.40.128.260; -; 1.
DR   Gene3D; 2.60.40.2500; -; 1.
DR   Gene3D; 2.70.20.10; -; 1.
DR   HAMAP; MF_00952; Topoisom_1_prok; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR004346; CagE_TrbE_VirB.
DR   InterPro; IPR018145; CagE_TrbE_VirB_cntrl_dom.
DR   InterPro; IPR008635; Coiled_stalk_dom.
DR   InterPro; IPR010258; Conjugal_tfr_TrbG/VirB9/CagX.
DR   InterPro; IPR007688; Conjugal_tfr_TrbL/VirB6.
DR   InterPro; IPR040677; LPD7.
DR   InterPro; IPR023346; Lysozyme-like_dom_sf.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001482; T2SS/T4SS.
DR   InterPro; IPR005498; T4SS_VirB10/TraB/TrbI.
DR   InterPro; IPR042217; T4SS_VirB10/TrbI.
DR   InterPro; IPR014158; T4SS_VirB5.
DR   InterPro; IPR023220; T4SS_VirB5-domain.
DR   InterPro; IPR000380; Topo_IA.
DR   InterPro; IPR003601; Topo_IA_2.
DR   InterPro; IPR013497; Topo_IA_cen.
DR   InterPro; IPR013824; Topo_IA_cen_sub1.
DR   InterPro; IPR013825; Topo_IA_cen_sub2.
DR   InterPro; IPR013826; Topo_IA_cen_sub3.
DR   InterPro; IPR023405; Topo_IA_core_domain.
DR   InterPro; IPR003602; Topo_IA_DNA-bd_dom.
DR   InterPro; IPR005733; TopoI_bac-type.
DR   InterPro; IPR028612; Topoisom_1_IA.
DR   InterPro; IPR006171; TOPRIM_domain.
DR   InterPro; IPR034149; TOPRIM_TopoI.
DR   InterPro; IPR003688; TraG/VirD4.
DR   InterPro; IPR008258; Transglycosylase_SLT_dom_1.
DR   InterPro; IPR007039; TrbC/VirB2.
DR   InterPro; IPR009989; TrbM.
DR   InterPro; IPR014155; VirB11.
DR   InterPro; IPR007430; VirB8.
DR   InterPro; IPR014148; VirB9.
DR   InterPro; IPR033645; VirB9/CagX/TrbG_C.
DR   InterPro; IPR038161; VirB9/CagX/TrbG_C_sf.
DR   PANTHER; PTHR42785; PTHR42785; 1.
DR   Pfam; PF03135; CagE_TrbE_VirB; 1.
DR   Pfam; PF03524; CagX; 1.
DR   Pfam; PF18821; LPD7; 1.
DR   Pfam; PF01464; SLT; 1.
DR   Pfam; PF00437; T2SSE; 1.
DR   Pfam; PF07996; T4SS; 1.
DR   Pfam; PF02534; T4SS-DNA_transf; 1.
DR   Pfam; PF01131; Topoisom_bac; 1.
DR   Pfam; PF01751; Toprim; 1.
DR   Pfam; PF04956; TrbC; 1.
DR   Pfam; PF03743; TrbI; 1.
DR   Pfam; PF04610; TrbL; 1.
DR   Pfam; PF07424; TrbM; 1.
DR   Pfam; PF04335; VirB8; 1.
DR   Pfam; PF05662; YadA_stalk; 9.
DR   PRINTS; PR00417; PRTPISMRASEI.
DR   SMART; SM00382; AAA; 2.
DR   SMART; SM00437; TOP1Ac; 1.
DR   SMART; SM00436; TOP1Bc; 1.
DR   SMART; SM00493; TOPRIM; 1.
DR   SUPFAM; SSF52540; SSF52540; 3.
DR   SUPFAM; SSF53955; SSF53955; 1.
DR   SUPFAM; SSF54427; SSF54427; 1.
DR   SUPFAM; SSF56712; SSF56712; 1.
DR   TIGRFAMs; TIGR01051; topA_bact; 1.
DR   TIGRFAMs; TIGR02788; VirB11; 1.
DR   TIGRFAMs; TIGR00929; VirB4_CagE; 1.
DR   TIGRFAMs; TIGR02781; VirB9; 1.
DR   PROSITE; PS50880; TOPRIM; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005237};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005237};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1272   1290       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1310   1329       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2556   2580       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2592   2611       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2675   2695       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2701   2719       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2726   2744       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2870   2892       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   3881   3902       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   3939   3958       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      475    591       Toprim. {ECO:0000259|PROSITE:PS50880}.
FT   REGION      210    234       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1214   1241       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     2809   2832       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     3298   3340       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     3369   3431       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     5327   5361       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COILED     1786   1806       {ECO:0000256|SAM:Coils}.
FT   COILED     2294   2328       {ECO:0000256|SAM:Coils}.
FT   COILED     2835   2855       {ECO:0000256|SAM:Coils}.
FT   COILED     3695   3715       {ECO:0000256|SAM:Coils}.
FT   COILED     5217   5237       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS    220    234       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   3298   3325       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   3369   3383       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS   3411   3430       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   5327   5343       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   6545 AA;  708819 MW;  59C756BB30A9BDA1 CRC64;
     MTSALAQPAT AKLSDTTATI PANILELIGT CAPDVHPNTM WKILGHESGF TPFIIGVNEK
     GKDRQVFRLK TQQEAGQKAR ELIAQGKSID MGLGQIWSGN LRGLKLTPEE VFEPCTNVAA
     AAGLLMEAYE RALKQGFTDA KAMDQALSLY NTGKFDNGIA NGYVSKVRGK RYKVPAMDGE
     AGEAAQPPAV LQAKPEAPPP AWDVFANARY RGPRPDETAN PPSGEQQTAA AEPASVGATH
     SLMVDDVPRV DAQARLRRAH VRIAQLEFES RAIHAIALGR RKNLQDLSPA EVIEAGEAAG
     LFIVSDAPAP KLVPLTSFET HCPGCRGLMR TMTPTGCEMA VAKSAYGYDG DCIPGVPVQF
     AGCASAAMAT VGECPHCAAL YWSLDLVLHT DLTWEAVEAI LADDPEWDAS FIVGANWTAH
     AITTDSGKGY EHFIGPLLIP SARACRVRVI QTAIGGGAAR AGASRVRIGG HAGMTTLMIV
     ESPAKAKSIG GYLGPDFVVM ASYGHIRDLP ATGQQDGELT VGVDSNFALR YEVGSDRAKA
     TVGRLREAVK KATRVVLATD PDREGEAIAW HLQQALRLKN PERVTYQEVT ATAVRAALAK
     PRTIDTKLVH AQEGRRALDR LVGYTVSPKL SQSAGEKLSA GRVQTPALRL VVEREREIRG
     FKVQLHYGAE LTFEGGWKAT WTVKPHLVSG AEYWTDRETA SRIAGVRRLL VHDFTDGKAK
     EAPPAPFTTS TLQQEGGKRL GLSVKEVMDA AQVLFDSGLI TYHRTDSPNF LDDGYALISA
     YALEAGLPLA PERRSWKVKA GAQEGHEAIR PTKLAVEAAG SNETERQLYA LIRMRALASQ
     LADATYATRT VKLGALDTDA VNDVLPGFEA KGRVLIDRGW RVVYAGDAKD ADEDASDDEQ
     ALSNPIPVLA VGSEISAADG RLLEKKTAPP KRYTEAGLVK KLEELGLGRP ATYASILGNI
     TARSYITVEG GKHKVLAPTQ TGERLIDAVV GKCRFADYDF TAGMEDQLDQ VAAGKRPYAD
     VVGAAWRQLE SELPGLQMTA AEPEHKCPDC SRGLRRIKGA NGFFWACTGY SADPQCKTTL
     PDARGKPGKR AEASTEHKCE DPACGKPLIH RVKKETKAAK GYDFWGCSGF PTCKRNYKTG
     PDGKPVMNDN TQPTGVITSM LHIDEQALTL LLQTGGITQI ELRPAGRGYG VFVCMDRKED
     GPSTAMLITA RMKHQKRKST SIKGETTRKP PRTTRSSRRL TGVSQSIPNC LESYNMQATS
     LGERTRSTNR TFVTAVLMAA ALAMLPDLAF AQAAPWEQTA QNTYNLIMSI VRWVAIIGVV
     GCGVAAMFGK LSWDWAGKII IGLVLIFGGT QLVDYFRRSL VRRCHPTGNG RGHHLRGDRF
     HRDGGGHGIR HYGEFPVAAC LRAAPRHRVR DLQERPACLP PPVPDACEQG ALHEPRDLGL
     RLLFTAAIQE EKMNRSQAAT NREVPVSKTI PYRSHVSPYV VNTEAGDLVT VFKVSGVAHE
     SADVEDVDSW HTRLNGLLKT IQSPNVTLWT HTIRQKRGEY PQGDFVRGSF AAEVDGAYRG
     RVTQTEMMAN DLYVTVVYSP NENKLKKLVA KIFDRLDPAE VRAKVEDALE AIEDVARQVK
     AGLGEWGPVR LGWYEEDGVT YSEVMELFGY LLNMEWQRWP VPRLNPGVDT TIAGVLATAR
     PFMGAEAFEI RGATKSRVGG ILALKEYPAW TSPGFVNKLL SLPCEFILTQ SFRFIPKQAA
     LGMLVRQQSK MVQSGEVSDS LVQQMNDALD HLSAGRFVMG EHHLSLTLLA GTVKELNDNI
     AEAKSNLSDC GGVPAREDWG LEAAFWAQLP GNFRWRSRPA PVTSFNFAGF CAMHNYPTGL
     AAGNQWGPAV TMFKTASGTP YYFNFHLPPK KRKRGRDALR QVEVKVDDRV AGNTLIIGPT
     GSGKTVVQTL LLAQLEKFKP TIFYYDKDRG MEIFFRALGG NYLTIENGIP TGFNPFRIEP
     NAGNVSFLQT IVRKLVKAGG DVHLTPVEEK DIDNAIDGVL GLPEEMRRLG SMLQFMDPTD
     PAGPAARLER WCAGGALGWV FDNEVDEIDP NKNRINGFDI TDLLDNDQVR EPVLMYLLHR
     QEEVIDGRRV VLGFDEGWKV LYDEWLSAYV ENKELTIRKQ DGFVIFGTQN PSHVIKSRIA
     DTLVQQSVTQ IYMPNDKASR EDYINGFKLS EREYEIIKDV MPAMPGRYFL VKQGKHSAIC
     ELDLAGLDNI LAVLSGTTST VELLNHIRAE LGPDCTPADW LPALVVGVAL AIGGGAITAP
     AFASGVPTVD VAAIAQMIQQ FQMLEKQLTN MQDQLKQAEQ QVNAVTGKRG MEKMLRNEAE
     GLIPTNWQET LAQMNGGKIG NLAQSIKQNA SRVDSGLLNR LLPSESASAS DSFANSAANA
     QATAGQAYEL SGQRFTRLQK LMDEIGNTTD AKGIAELQAR IGVEQAILQN ETIKMQALAQ
     TASAQQAIQQ QQMREMTLDR ASTSNSMPSP KGQARSRRLR QLCPRDASGC DGQAFGHEPV
     GEEAVMATSN LQLYSWLYAQ FDSVLTGYIA QTSGQIVGAI TPVAYIMFGI YIVLWGFSMV
     RGLIDEPVTD GLFRLLKIAL ILGFALNTGR YQVEVVEFFM RTPDALANVL ALKGSAAAGD
     VSTFQTLDTL INRTVDVART AWNEAGVFNG NMGMYLAAAM VLVFGLLFSA AAGIIVLVGK
     IAMVLLLALG PIFILMTMFK TTQRFFDAWL GQVINYMILL GAGLGRGHDV HVHHGDRRAE
     RRREDAGQVH SRSNFHDHPG VNLLHGPAVP GRADRQCLGG RCRAGHHRGR GPCGCPTATT
     GPSTSRSRSP ENRRMAKATE AMTEKQQTYA ELTKAFESDV VTSARRSAKL AWLGCILLGV
     VAVAQGLAIF GLTPLHRIEP YVVRVDEATG AVDSVAKLNA TSRTETEAVN KYMVGKYVRA
     REEYSAQLAP VNYKTVALMS APPVANLYHE AFKPENPKSP LKVYAGGGNV NIRILNVSFL
     GPNIASVRYE KTIRANDAVT RSMWLATVTF RYSNAPMSED DRLVNPIGFE RAFLAAAMTL
     ATAGAHAEVL PTGGAADLRV KTVNYDGSNV VRIVGHYGFV THIQLGEGET VGSVAMGDSL
     AWEVAPTGNH LFVKPREPNA TTNMSVVTKP NNRVYQFVLT AHQSQNGARP RPNDMFFAVN
     FRYPEDERRA KAAASDKAKA ESSLAMTRIV GKNFNYWACG SKAVAPDQAM DDGRFTYLRF
     SANRDMPAVF EELSKGKEAL VNTHVEGDWI VVQRVLPRLI LRRGDQVACV ENRSFDPNGV
     STPTSTPITG NVMSENDTNQ EAPSQLGEER GVPSVNKRKK NGKAGKIFGA AAMVGLVAVM
     GWMQFAPKEA PEARKEEEST QARRGLPDLT MPVTEVPPAP PVEEAKPTTA SLAAPASNPS
     MDSPQQPRQP TEAELLLERR KRAPIFAFGN AGGEAASGGN GAGGAASLDA GNGGSLGGDG
     EDGPDRNSLA VNLQSTKFES SRASMLTNRN FLLTAGTMLD CTLVTALDST LPGKTKCQLS
     RNIYSDNGKV LLLERGSIVE GACMTSAATN HRPDHALRQY MAPLAKLLAE NVTEVCVNRP
     GEAWTESQAG WQRHEMPELT YPKLKQLGSL IATFNQSGFR EDSPYLSGVM PDRERVQVVM
     APATTEGTIS FTIRKPSLTE KTLEELDGEG SFAGAQLARE GLTEVDEQLV RLRNERRFRE
     FLDLAVQAKK NILLAGATGS GKTTVMRALV ARIPHSERVI TIEDAHELFM EGHPNKVHLF
     YRAARPGEAG VQLTAQEALR SCMRMKPDRI LLAELRGAEA WDYMDSLNTG HPADVLRDDR
     RGALLPEAED AGTVFRSASP AGLVARQLDP LGGSMSKQPP MWAKVVIGVV LVGVMVACWA
     RLGAEIFVPL AKVNVEPGFL TLYQYWQHYG DQHRLMQHMY VAMGGASLPF VFLGWLIFSK
     RDDRPLHGAA RFAKLSEIKK AGLLGDKGIL VGKLGDDYLM YSGDSHARVA APTRGGKGVG
     IVIPNLLNWG ESAVVLDIKQ ENWDLTSGFR TACGQACYLF NPGARDGRSH GWNPLHYVAD
     EPGARVNDIQ KIAGMIWPDP ADGGDPIWTA SCRSLFLGTV LYLMETPGEP VTLGGVLRFG
     MRATAKSLKA KLASRQESDD PLSAECIMAL SDYLDTSDNT RTSIRKSFTS RLELWQNPMI
     DAATSRNDFD LRDLRRKPMT IYIGITPDDL DRLAPIINLL FQQIIDLNTR QLPHQVGPDE
     LPLKYKCLLL MDEFMALGRI PILQKGISYI AGYGLRILAI FQSPGQVRDP RAGYGPDGAD
     TIFDNMDVNV VFTPANIRIA EEISKELGTE TVKKKSKGKS GIAFKSKSHS ENESEHSRAL
     LLPQEVKEIG QWEEILFVRG TKAIQCEKAR YFLDPVFTDR LRSVSKILQE GCEEGMPPAR
     ELLEHAAQSG SLAAPVPVLT PVQMGLQDAA KLALAQLDDS PSRPVTAEDM ENLQNLGADD
     FDMNFSDGGE PNGAQLAAAA RLRNDLDRDG TQDHLAGTSA DSRARPDWET FAREREDERE
     RLQSNYQARR SDLHQAGAEL HTAMGNDPRI AESSLHGELG ESLKAENAAF PLRMTQAINA
     AKAELDRRAK EPGDKAAEAW KVGEVRVGVV AASAAYERAR MELAENTNLQ YSVDRSARNL
     RDAGLQLQDG MSRDPQWQGT AAEAELQASL QEDVARRHPE RMALAVRDVV DELDRQAHEG
     KAAGQMWQDS DLREQVIQRH DQFVRDMGNL DVARRQAAAE RAMDAQRQAA DLGGFADAAA
     PAWEAQHDPV EARELRDEAK AFNAGAALDN IPFSAHGNLE LLRAYREGVT TTEEKLLGDE
     PEKVRSEQWE RLREQLGKVD HSIALMENRE RSEAEFAKAF AAGHSLEDLP ASAGQNLAFI
     MTHAKGLADR ERMLRQQPAE TVATELAQLQ VQLEKSAKAI EAATPGLDRA PESETPSWRS
     GFTEADARFS DQLEAEHNAA VAQMQNRDLI DQHIHNQINL GELHEDLHTR AKLEGRELNA
     EELERSRHYE SEIAGLQGEI DVLSGRLPQP PERVREDKDA QVEQAEANNG RWTVQQYDAE
     RGVYRDTLTT DHALAAYTEV RKSDYHRVLD NDLKDVAADY YDVDLGDGNY PRQFAFHARS
     TFEREVASQD VGDTLQSVLE RRAQLDATVL QRSDAISEAV DKVHDTQVSD ADLVAGYATA
     ARSYAEATRE RAEFEQQPSE NARVTDAYHN VVNHEATIAL LRHNEAAARG NGNDQAAQET
     AKAREAEQAE LARLLTVNGV TKGYRPPENV RNEIEVALSK EQIDRLTGNG KSKVEKDQEA
     DASKTARVVT PPPLPNISEG HNQVRNFSAF ADAGAKDKLI PEDVAARYKK DGQKFLDAND
     PKKVAFVDKG NRLQTSRSFD DKAVEDMVAI AHARGMTAIK VSGDEGFRRK AWIEGTASGM
     DVTGYEPTEK DKLRADQLAK QTGRANAIEK NEVVEAYRAA RDGSVQDKKE AAKKHPELAN
     AFALEQAAKS FAKQRLAPES QEKLVSTIRD SIERDLAQGK KIPEVMTMNN TLMVTVMVGA
     LVAGSVGSAK AQDVLTGDKK LACEAILCLA AVGQRPGECS ASIAKYFSIT ASKPSRLKAK
     RKDFLKMCPS GDDNLVNSLV SGKCNPTYQD CAAAGGGAGI DVTTSFTTLP RRLVAGTSIL
     ALLVGAPPAF AEFPAPPSAP CEGVGNCADD GLRYTDWSFV TQEVSEHADG SGERVQNYMA
     VGPDGWRING IGEGVLYTYI TGSDEYGNPI VEYATSYASA PVMLNAGQTI NMAKASAIPG
     GARIMNLADG IDGMDAVNKR QLDAAMQNAG GNDPLAVKYT DGNRNMVSIG GRMVNLTDGQ
     NWNDAANMGQ LWGVRDLAQD GVNRANTAQG RADAATTQAV GAFNHAEDAR NAALTAQARA
     DKGVNDAATA LSRAEVGVHD ASLAQSRANY AVSAAATAQL QADKGVTDAA AAQSSADRVG
     VDLAALDARA VQFGGNGAIQ AKGARLSNLG DGVDASDAVT KRQLDALAGD VGGIAGDALQ
     FDGTTYNATR GGQSTRISGV ADGTDAGDAV NRRQLDGVEG QAREAQRTAD RVGVDLAALD
     ARAVQFTGPN GAIAAKGSRL VDLADGVDAT DAVNKRQLDA VAGDVANVGR DALLFDGQAY
     NATRGGQRTR ITGVADGVED SDAVNRGQLN TVRNDLQALD DVAVKYTDSS RTAISLGDGS
     RAVRMSNVAE GVATTDAVNK GQLDAVAADL GAVANDALMY DGQAYNATRG GQATRITGVA
     AGTSSSDAAN FGQLDAVASI FGAGGRWANG SYVAPTFVIG GQSFTTVGDA FAAVDGRLAG
     IEDRVTDVEE RPTSTRGVTY DDQSRDAVTL EGKSGTRVSN VADGKADTDA ANVRQVKQAE
     SNSKTYTDTK ATETLQTANS YTDRRVNDVS HGLNELGNRV ERGFQQTNKR ISRQSAMTAA
     MVQMGINAAG GRSERGRLAF GMGFADGEAA FSAGYGKSFG RGSFSVGGSF SGGEVSVGMG
     VGFDM
//
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