GenomeNet

Database: UniProt
Entry: K7IYH0_NASVI
LinkDB: K7IYH0_NASVI
Original site: K7IYH0_NASVI 
ID   K7IYH0_NASVI            Unreviewed;       643 AA.
AC   K7IYH0;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   31-JUL-2019, entry version 42.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:NV14143-PA};
GN   Name=100123847 {ECO:0000313|EnsemblMetazoa:NV14143-PA};
OS   Nasonia vitripennis (Parasitic wasp).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Hymenoptera; Apocrita; Parasitoida;
OC   Chalcidoidea; Pteromalidae; Pteromalinae; Nasonia.
OX   NCBI_TaxID=7425 {ECO:0000313|EnsemblMetazoa:NV14143-PA, ECO:0000313|Proteomes:UP000002358};
RN   [1] {ECO:0000313|EnsemblMetazoa:NV14143-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AsymCX {ECO:0000313|EnsemblMetazoa:NV14143-PA};
RX   PubMed=20075255; DOI=10.1126/science.1178028;
RG   Nasonia Genome Working Group;
RA   Werren J.H., Richards S., Desjardins C.A., Niehuis O., Gadau J.,
RA   Colbourne J.K., Werren J.H., Richards S., Desjardins C.A., Niehuis O.,
RA   Gadau J., Colbourne J.K., Beukeboom L.W., Desplan C., Elsik C.G.,
RA   Grimmelikhuijzen C.J., Kitts P., Lynch J.A., Murphy T., Oliveira D.C.,
RA   Smith C.D., van de Zande L., Worley K.C., Zdobnov E.M., Aerts M.,
RA   Albert S., Anaya V.H., Anzola J.M., Barchuk A.R., Behura S.K.,
RA   Bera A.N., Berenbaum M.R., Bertossa R.C., Bitondi M.M.,
RA   Bordenstein S.R., Bork P., Bornberg-Bauer E., Brunain M.,
RA   Cazzamali G., Chaboub L., Chacko J., Chavez D., Childers C.P.,
RA   Choi J.H., Clark M.E., Claudianos C., Clinton R.A., Cree A.G.,
RA   Cristino A.S., Dang P.M., Darby A.C., de Graaf D.C., Devreese B.,
RA   Dinh H.H., Edwards R., Elango N., Elhaik E., Ermolaeva O., Evans J.D.,
RA   Foret S., Fowler G.R., Gerlach D., Gibson J.D., Gilbert D.G.,
RA   Graur D., Grunder S., Hagen D.E., Han Y., Hauser F., Hultmark D.,
RA   Hunter H.C. IV, Hurst G.D., Jhangian S.N., Jiang H., Johnson R.M.,
RA   Jones A.K., Junier T., Kadowaki T., Kamping A., Kapustin Y.,
RA   Kechavarzi B., Kim J., Kim J., Kiryutin B., Koevoets T., Kovar C.L.,
RA   Kriventseva E.V., Kucharski R., Lee H., Lee S.L., Lees K., Lewis L.R.,
RA   Loehlin D.W., Logsdon J.M. Jr., Lopez J.A., Lozado R.J., Maglott D.,
RA   Maleszka R., Mayampurath A., Mazur D.J., McClure M.A., Moore A.D.,
RA   Morgan M.B., Muller J., Munoz-Torres M.C., Muzny D.M., Nazareth L.V.,
RA   Neupert S., Nguyen N.B., Nunes F.M., Oakeshott J.G., Okwuonu G.O.,
RA   Pannebakker B.A., Pejaver V.R., Peng Z., Pratt S.C., Predel R.,
RA   Pu L.L., Ranson H., Raychoudhury R., Rechtsteiner A., Reese J.T.,
RA   Reid J.G., Riddle M., Robertson H.M., Romero-Severson J.,
RA   Rosenberg M., Sackton T.B., Sattelle D.B., Schluns H., Schmitt T.,
RA   Schneider M., Schuler A., Schurko A.M., Shuker D.M., Simoes Z.L.,
RA   Sinha S., Smith Z., Solovyev V., Souvorov A., Springauf A.,
RA   Stafflinger E., Stage D.E., Stanke M., Tanaka Y., Telschow A.,
RA   Trent C., Vattathil S., Verhulst E.C., Viljakainen L., Wanner K.W.,
RA   Waterhouse R.M., Whitfield J.B., Wilkes T.E., Williamson M.,
RA   Willis J.H., Wolschin F., Wyder S., Yamada T., Yi S.V., Zecher C.N.,
RA   Zhang L., Gibbs R.A.;
RT   "Functional and evolutionary insights from the genomes of three
RT   parasitoid Nasonia species.";
RL   Science 327:343-348(2010).
RN   [2] {ECO:0000313|EnsemblMetazoa:NV14143-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (MAR-2014) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   RefSeq; XP_016838507.1; XM_016983018.1.
DR   STRING; 7425.NV14143-PA; -.
DR   EnsemblMetazoa; NV14143-RA; NV14143-PA; NV14143.
DR   GeneID; 100123847; -.
DR   eggNOG; KOG3827; Eukaryota.
DR   eggNOG; ENOG410XQ62; LUCA.
DR   InParanoid; K7IYH0; -.
DR   OrthoDB; 377675at2759; -.
DR   PhylomeDB; K7IYH0; -.
DR   Proteomes; UP000002358; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002358};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002358};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM    108    131       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    191    215       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       74    220       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      227    399       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION        1     28       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      423    482       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      493    512       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      520    643       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    423    437       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    579    593       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    626    643       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   643 AA;  72375 MW;  067245D7874EE151 CRC64;
     MEDEEEQEEP PPVPIGIRPS ASAPSRLRNP SLVFASSRRN ASRASIRTEA GPLVANRYRQ
     TRFSSRRVRK RVVFKHGDCN VVQGNVAKRR RRYLQDIFTT LVDAQWRWTL LVFAMTFLLS
     WLGFALVWWL VVYAHGDLEA KIAAGEPGSN VSFTPCVEDI HGFTSCFLFS VETQHTIGYG
     SKHTTEECPE AIFIMCIQSM TGVILQAFMV GIVFAKLSRP KKRTQTLLFS RNAVICQRDG
     QPCLMFRVGD MRKSHIIEAH VRAQMIKRKV TREGELLPFF QTELKVGGDG EEDKIFFIWP
     TTIVHKINEQ SPLYHLSASD MLRERFEIIV MLEGVIESTG MTTQARSSYL PSEILWGHRF
     EHIITFRKET GEYEVNYTLF NNTYEVDTPL CSAAELDHVR AMHRAKGERT SSATFAQYRM
     DSSSSLSSGS ASSFASSAGG LHMMPPQAHA TTPPTPIPVM ITAPEDSPSR RGSGSQPGEP
     RRKFATFYTL DETIEPDERT SHFHRAVDQP NSIQVLNDVE EQDEEDEGNL KPLLPNRGHH
     GSPPPFIQPK IIDDHGANNT GLRLHSRRPS IPDSKPANSS NKKVEERNSQ PRDTRRSSIN
     SIGNRRARKN VELIAPEPST NLLRESMPPP PQTSNCNGPK ELV
//
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