ID K7K518_SOYBN Unreviewed; 679 AA.
AC K7K518;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 22-FEB-2023, entry version 49.
DE RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN Name=100819924 {ECO:0000313|EnsemblPlants:KRH77388};
GN ORFNames=GLYMA_01G210600 {ECO:0000313|EMBL:KRH77388.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EnsemblPlants:KRH77388};
RN [1] {ECO:0000313|EMBL:KRH77388.1, ECO:0000313|EnsemblPlants:KRH77388}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRH77388};
RC TISSUE=Callus {ECO:0000313|EMBL:KRH77388.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [2] {ECO:0000313|EnsemblPlants:KRH77388}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRH77388};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [3] {ECO:0000313|EMBL:KRH77388.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRH77388.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in the transport of sterols.
CC {ECO:0000256|ARBA:ARBA00003361}.
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DR EMBL; CM000834; KRH77388.1; -; Genomic_DNA.
DR AlphaFoldDB; K7K518; -.
DR EnsemblPlants; KRH77388; KRH77388; GLYMA_01G210600.
DR Gramene; KRH77388; KRH77388; GLYMA_01G210600.
DR Proteomes; UP000008827; Chromosome 1.
DR ExpressionAtlas; K7K518; baseline and differential.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR Gene3D; 2.40.160.120; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR037239; OSBP_sf.
DR InterPro; IPR000648; Oxysterol-bd.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10972; OXYSTEROL-BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR10972:SF88; OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 2B; 1.
DR Pfam; PF01237; Oxysterol_BP; 1.
DR Pfam; PF15413; PH_11; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF144000; Oxysterol-binding protein-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000008827};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 51..186
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
SQ SEQUENCE 679 AA; 77156 MW; E75D318A97C6A223 CRC64;
MRVKEMHPLC CISLESPGIG KYSPEREPAA LFRTRSLPAA GSHGNAAQGS ETTVAGVLYK
WTNYGKGWRS RWFLLRNGVL SYAKIRCPEN LNLLTPSDDV RLIGEISTNR LARVDSAATV
TRRKHRKASS SSSSGVVHLK QISSFRESKS DDRRFYIFTA TKTLHLRTDS RKDRVAWIQA
LVSTRGLYPL QPLNDHLLLA PNDISLSTER LKTRLLEEGT GENLVKECEQ IMLSEFSEMQ
GQLEVLCQER SNLLDTIRQL EAANTEPEAS AIHDGEYQLT KNEFSSLGRG KYSECSTTES
SDDIEKQEME EVSDEDEISY YDTRECFTEP DCKCESAEAM NQVDRCREAN TQYTDTENIH
PEKMVCNYKH PQLARRKKLP DPVEKEKGVS LWSMIKDNVG KDLTRVCLPV YFNEPISSLQ
KCCEDLEYSY LLDQAYEYGK SGNGLLRALY VAAFAVSGYA SSEGRNCKPF NPLLGETYEA
DYPDKGIRFF SEKVSHHPTL IACHCEGRGW KFWADSNIHS KFWGRSIQLD PVGVLTLEFS
DGEIFQWSKV TTTIYNLILG KIYCDHHGSM DIRGNRTYSC RLKFKEQTIL DRNPRQVHGF
VEDVTGKRVA TLFGKWDDNM YYMSGNINVK PKDFTSANAS LLWKRTMPSP NLTRYNLTPF
AITLNELTPG LKLFLIPGI
//
