ID K7KB78_SOYBN Unreviewed; 869 AA.
AC K7KB78;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 08-NOV-2023, entry version 67.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=100820132 {ECO:0000313|EnsemblPlants:KRH73541};
GN ORFNames=GLYMA_02G279300 {ECO:0000313|EMBL:KRH73541.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EMBL:KRH73541.1};
RN [1] {ECO:0000313|EMBL:KRH73541.1, ECO:0000313|EnsemblPlants:KRH73541}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRH73541};
RC TISSUE=Callus {ECO:0000313|EMBL:KRH73541.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [2] {ECO:0000313|EnsemblPlants:KRH73541}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRH73541};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [3] {ECO:0000313|EMBL:KRH73541.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRH73541.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM000835; KRH73541.1; -; Genomic_DNA.
DR RefSeq; XP_006575623.1; XM_006575560.2.
DR AlphaFoldDB; K7KB78; -.
DR EnsemblPlants; KRH73541; KRH73541; GLYMA_02G279300.
DR GeneID; 100820132; -.
DR Gramene; KRH73541; KRH73541; GLYMA_02G279300.
DR HOGENOM; CLU_011283_1_0_1; -.
DR OrthoDB; 5395569at2759; -.
DR Proteomes; UP000008827; Chromosome 2.
DR ExpressionAtlas; K7KB78; baseline and differential.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00821; PH; 1.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR025757; MIP1_Leuzipper.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR46265; RHO GTPASE-ACTIVATING PROTEIN 7; 1.
DR PANTHER; PTHR46265:SF2; RHO GTPASE-ACTIVATING PROTEIN 7; 1.
DR Pfam; PF14389; Lzipper-MIP1; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008827}.
FT DOMAIN 18..125
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 172..372
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 382..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 454..572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 756..795
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 603..637
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 662..696
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 823..850
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 454..480
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..518
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..566
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 869 AA; 95910 MW; 84C7345278DF4CEA CRC64;
MSAPLAAFER PRPGASNTVF KSGPLFISSK GIGWKSWKKR WFILTRTSLV FFKNDPSALP
QRGGEVNLTL GGIDLNNSGS VVVREDKKLL TVLFPDGRDG RAFTLKAETS EDLLEWKTAL
EQALTQAPSA ALVMGHNGIF RSDASDSIEG SFHQWRDKRP IKSLVVGRPI LLALEDIDGG
PSFLEKALRF LEKYGTKVEG ILRQSADVEE VDRRVQEYEQ GKTEFGPEED AHVVGDCVKH
VLRELPSSPV PASCCTALLE AYKIDRKEAR INAMRCAILE TFPEPNRRLL QRILKMMHTI
GSHSQENRMT PSAVAACMAP LLLRPLLAGE CELEDEFDAS GDSSAQLLAA ANAANNAQAI
ITTLLEEYES IFDEENIQRC SMSADSRVEN SGSEDSTDDD NIDVKENGYH DAENEVDQET
DDDADRVQSG KLSESSGYAG SDLYDYKAFG GDDSDVGSSS SNHAKTENAN LNAVPDTPGS
EDQNKQRKAS ENPVDENDAS NLLPSSESYR SMGEILSSMD PSNHLPMPVI ESGSGKQTSK
ASSTSFSSKR STFWGRSNPR KTPSVESVDS SGEEELAIQR LEIAKNDLQH RIAKEARGNA
ILQASLERRK QALHERRLAL EQDVSRLQEQ LQAERDLRAA LEVGLSMSSG QLSSSRGMDS
KTKAELEEIA LAEADVARLK QKVAELHHQL NQQRQHHYGS LTDVGDRYQH AQNHPQQRFL
QQDFDSTLAF VNHERKQRTE ESLLGTDWRN IKGQVLASGN GTRQPSRKQF LESSPSDSKS
TEASTSMSVD DLGAIDSASV PSTSRVADVG EYARHPPVAS STLVELTTRL DFFKERRSQL
MEQLHNLDLN YGSTTSQDFV YKPSSPSWS
//
