ID K7MFR5_SOYBN Unreviewed; 693 AA.
AC K7MFR5;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Mechanosensitive ion channel protein {ECO:0000256|PIRNR:PIRNR017209};
GN Name=100808521 {ECO:0000313|EnsemblPlants:KRH07222};
GN ORFNames=GLYMA_16G075000 {ECO:0000313|EMBL:KRH07222.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EnsemblPlants:KRH07222};
RN [1] {ECO:0000313|EMBL:KRH07222.1, ECO:0000313|EnsemblPlants:KRH07222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRH07222};
RC TISSUE=Callus {ECO:0000313|EMBL:KRH07222.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [2] {ECO:0000313|EnsemblPlants:KRH07222}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRH07222};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [3] {ECO:0000313|EMBL:KRH07222.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRH07222.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|PIRNR:PIRNR017209}.
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DR EMBL; CM000849; KRH07222.1; -; Genomic_DNA.
DR RefSeq; XP_003548581.1; XM_003548533.3.
DR AlphaFoldDB; K7MFR5; -.
DR STRING; 3847.K7MFR5; -.
DR PaxDb; 3847-GLYMA16G08150-2; -.
DR EnsemblPlants; KRH07222; KRH07222; GLYMA_16G075000.
DR GeneID; 100808521; -.
DR Gramene; KRH07222; KRH07222; GLYMA_16G075000.
DR KEGG; gmx:100808521; -.
DR eggNOG; KOG4629; Eukaryota.
DR HOGENOM; CLU_013552_1_0_1; -.
DR InParanoid; K7MFR5; -.
DR OMA; TCFQKEE; -.
DR OrthoDB; 11155at2759; -.
DR Proteomes; UP000008827; Chromosome 16.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0050982; P:detection of mechanical stimulus; IBA:GO_Central.
DR GO; GO:0006820; P:monoatomic anion transport; IBA:GO_Central.
DR Gene3D; 2.30.30.60; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR016688; MscS-like_plants/fungi.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR PANTHER; PTHR31618:SF10; MECHANOSENSITIVE ION CHANNEL PROTEIN; 1.
DR PANTHER; PTHR31618; MECHANOSENSITIVE ION CHANNEL PROTEIN 5; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR PIRSF; PIRSF017209; Memb_At2g17000_prd; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR017209};
KW Reference proteome {ECO:0000313|Proteomes:UP000008827};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00023065}.
FT TRANSMEM 126..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..491
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 516..572
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 79..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..106
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 693 AA; 80541 MW; 140A79ACCA16B902 CRC64;
MEKTRPSDQV VLFLDQHNPK PPSIESENHQ NKPKHPLKVR TLNRLSFSKP KSRILEYNYN
VPRNKVAISE EISDVIQPTY KLSSNDDDKE DDEDDCEWDE DETEEDGSEH GPKLHQKRKC
KIKWRLMMEW ILFLNILTCL VCSLTISSIT NMHLLGLEIW KWCLMAMVTF SGRLVSGWLV
GLTVFIIERN FMLREKVLYF IYGLRKSIRN CMWLGLVLLS YWSVVFDDVQ KKNHKFLNKV
FQALVAVLVG ATIWLLKIVL VKMLASSFHV TTYFDRMKES VFHHYILETL SDPPMMDDVA
EQQHHLTRWN NAKNLNKSKK FGSRRIDMEK LRKLSMESTA SAWSVKRLVN YVRSSGLSTI
SRTVDDFGNA ESEINSEWEA RNCAQRIFKN VAKPGAKYIE EEDLMRFLKR VEIHTIFPLF
EGALETGHIS RSSFRNWVIR AYYERKALAQ SLNDTKTAVQ QLHKIASAIV SVIIIIVMLL
VMEVATLKII LFCITQTVLI GVAFQGTCKT VLEAIIFVFV MHPFDIGDRC VIDGVHMIVE
EMNILTTVFL RYDNEKIYYP NAVLLSKPIS NFYRSPEMCD SIDFTIDVST SMETILALKK
SIQMYIESKP KYWNPKHSMI AKGIENMDKL KLCLSVQHTI NHQNYGERNV RITELLLELK
KIFEIHGIKY HLLPQEIQIT HMNIEHGKVL FQS
//
