ID K7MP06_SOYBN Unreviewed; 1197 AA.
AC K7MP06;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN Name=100781090 {ECO:0000313|EnsemblPlants:KRH05917};
GN ORFNames=GLYMA_17G256200 {ECO:0000313|EMBL:KRH05918.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EMBL:KRH05918.1};
RN [1] {ECO:0000313|EMBL:KRH05918.1, ECO:0000313|EnsemblPlants:KRH05917}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRH05917};
RC TISSUE=Callus {ECO:0000313|EMBL:KRH05918.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [2] {ECO:0000313|EnsemblPlants:KRH05917}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRH05917};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [3] {ECO:0000313|EMBL:KRH05918.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRH05918.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CM000850; KRH05917.1; -; Genomic_DNA.
DR EMBL; CM000850; KRH05918.1; -; Genomic_DNA.
DR EMBL; CM000850; KRH05919.1; -; Genomic_DNA.
DR EMBL; CM000850; KRH05920.1; -; Genomic_DNA.
DR RefSeq; XP_006601342.1; XM_006601279.2.
DR RefSeq; XP_014625284.1; XM_014769798.1.
DR AlphaFoldDB; K7MP06; -.
DR SMR; K7MP06; -.
DR STRING; 3847.K7MP06; -.
DR PaxDb; 3847-GLYMA17G37551-1; -.
DR EnsemblPlants; KRH05917; KRH05917; GLYMA_17G256200.
DR EnsemblPlants; KRH05918; KRH05918; GLYMA_17G256200.
DR EnsemblPlants; KRH05919; KRH05919; GLYMA_17G256200.
DR EnsemblPlants; KRH05920; KRH05920; GLYMA_17G256200.
DR GeneID; 100781090; -.
DR Gramene; KRH05917; KRH05917; GLYMA_17G256200.
DR Gramene; KRH05918; KRH05918; GLYMA_17G256200.
DR Gramene; KRH05919; KRH05919; GLYMA_17G256200.
DR Gramene; KRH05920; KRH05920; GLYMA_17G256200.
DR KEGG; gmx:100781090; -.
DR eggNOG; KOG0922; Eukaryota.
DR HOGENOM; CLU_001832_2_4_1; -.
DR InParanoid; K7MP06; -.
DR OMA; QRSESHI; -.
DR OrthoDB; 3682876at2759; -.
DR Proteomes; UP000008827; Chromosome 17.
DR GO; GO:0071013; C:catalytic step 2 spliceosome; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IBA:GO_Central.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0000390; P:spliceosomal complex disassembly; IBA:GO_Central.
DR CDD; cd17971; DEXHc_DHX8; 1.
DR CDD; cd21691; GH2-like_DHX8; 1.
DR CDD; cd05684; S1_DHX8_helicase; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR044762; DHX8/Prp22_DEXHc.
DR InterPro; IPR049588; DHX8_GH2-like.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049621; S1_DHX8_helicase.
DR InterPro; IPR003029; S1_domain.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF85; ATP-DEPENDENT RNA HELICASE DHX8; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR Pfam; PF00575; S1; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008827}.
FT DOMAIN 245..314
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 554..717
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 735..915
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 117..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 322..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..340
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1197 AA; 137038 MW; D7FD7F01FE85315B CRC64;
MAVENPEDGL KKLEYLSLVS KVCTELESHT GTGDKVLAEF ITELGRSSEN VEEFDEKLKE
NGAEMPDYFV RTLLTIIHAI LPPKPMDSKK EKDSVNGKTT KFKALAIADD RDRAKELQKE
LESEAREKQK PEIEEDDDGY RDRDRRDRRR DRYEDDRRDY GRRGRDRDDE DDRRDYGRRG
RDRDDEDDRR DYGRRGRDKY DRDRDRYERR RRDEHEEEHG RGRENGDRDG NRKGLQHGSG
ELELYAVYKG RISRVMETGC FVQLDDFRGK EGLVHVSQMA TRRITNAKDV VKRDQEVYVK
VISVSGQKLS LSMRDVDQHT GKDLLPLKKS SEDDALRMNP QDSKDGPVAR TGLSGIRIVE
EGDVGSSRRP LKRMSSPERW EAKQLIASGV LSVSEYPTYD DEGDGLLYQE EGAEEELEIE
LNEDEPAFLQ GQSRYSMDMS PVKIFKNPEG SLGRAAALQS ALIKERREVR EQQQRTMLDS
IPKDLNRPWE DPMPESGERH LAQELRGVGL SAYDMPEWKK DAYGKTITFG QRSKLSIQEQ
RQSLPIYKLK KELIQAVHDN QVLVVIGETG SGKTTQVTQY LAEAGYTTRG KIGCTQPRRV
AAMSVAKRVA EEFGCRLGEE VGYAIRFEDC TGPDTVIKYM TDGMLLREIL VDENLSQYSV
IMLDEAHERT IHTDVLFGLL KQLVKRRPEL RLIVTSATLD AEKFSGYFFN CNIFTIPGRT
FPVEILYTKQ PESDYLDAAL ITVLQIHLTE PEGDILLFLT GQEEIDFACQ SLYERMKGLG
KNVPELIILP VYSALPSEMQ SRIFDPAPPG KRKVVVATNI AEASLTIDGI FYVIDPGFAK
QNVYNPKQGL DSLVITPISQ ASAKQRAGRA GRTGPGKCYR LYTESAYRNE MSPTTIPEIQ
RINLGMTTLN MKAMGINDLL SFDFMDPPSP QALISAMEQL YSLGALDEEG LLTKLGRKMA
EFPLDPPLSK MLLASVDLGC SDEILTIIAM IQTGNIFYRP REKQAQADQK RAKFFQPEGD
HLTLLAVYEA WKAKNFSGPW CFENFVQSRS LRRAQDVRKQ LLTIMDKYKL DVVSAGKNFT
KVRKAITAGF FFHASRKDPQ EGYRTLVENQ PVYIHPSSAL FQRQPDWVIY HELVMTTKEY
MREVTVIDPK WLVELAPRYF KVADPTKMSK RKRQERIEPL YDRYHEPNSW RLSKRRA
//
