ID K7N5J8_SOYBN Unreviewed; 634 AA.
AC K7N5J8;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 24-JAN-2024, entry version 66.
DE RecName: Full=SAP domain-containing protein {ECO:0000259|PROSITE:PS50800};
GN Name=100775475 {ECO:0000313|EnsemblPlants:KRG93118};
GN ORFNames=GLYMA_20G248800 {ECO:0000313|EMBL:KRG93118.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EMBL:KRG93118.1};
RN [1] {ECO:0000313|EMBL:KRG93118.1, ECO:0000313|EnsemblPlants:KRG93118}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRG93118};
RC TISSUE=Callus {ECO:0000313|EMBL:KRG93118.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [2] {ECO:0000313|EnsemblPlants:KRG93118}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRG93118};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [3] {ECO:0000313|EMBL:KRG93118.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRG93118.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ku70 family.
CC {ECO:0000256|ARBA:ARBA00005240}.
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DR EMBL; CM000853; KRG93118.1; -; Genomic_DNA.
DR RefSeq; XP_006606601.1; XM_006606538.2.
DR AlphaFoldDB; K7N5J8; -.
DR SMR; K7N5J8; -.
DR STRING; 3847.K7N5J8; -.
DR PaxDb; 3847-GLYMA20G39280-2; -.
DR EnsemblPlants; KRG93118; KRG93118; GLYMA_20G248800.
DR GeneID; 100775475; -.
DR Gramene; KRG93118; KRG93118; GLYMA_20G248800.
DR KEGG; gmx:100775475; -.
DR eggNOG; KOG2327; Eukaryota.
DR InParanoid; K7N5J8; -.
DR OMA; FWANVKH; -.
DR OrthoDB; 21093at2759; -.
DR Proteomes; UP000008827; Chromosome 20.
DR ExpressionAtlas; K7N5J8; baseline.
DR GO; GO:0043564; C:Ku70:Ku80 complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0003690; F:double-stranded DNA binding; IEA:EnsemblPlants.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0042162; F:telomeric DNA binding; IBA:GO_Central.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IBA:GO_Central.
DR GO; GO:0009408; P:response to heat; IEA:EnsemblPlants.
DR GO; GO:0000723; P:telomere maintenance; IBA:GO_Central.
DR CDD; cd00788; KU70; 1.
DR CDD; cd01458; vWA_ku; 1.
DR Gene3D; 1.10.1600.10; -; 1.
DR Gene3D; 2.40.290.10; -; 1.
DR Gene3D; 4.10.970.10; Ku70, bridge and pillars; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR006165; Ku70.
DR InterPro; IPR006164; Ku70/Ku80_beta-barrel_dom.
DR InterPro; IPR027388; Ku70_bridge/pillars_dom_sf.
DR InterPro; IPR047087; KU70_core_dom.
DR InterPro; IPR005160; Ku_C.
DR InterPro; IPR005161; Ku_N.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR InterPro; IPR016194; SPOC-like_C_dom_sf.
DR InterPro; IPR036465; vWFA_dom_sf.
DR NCBIfam; TIGR00578; ku70; 1.
DR PANTHER; PTHR12604; KU AUTOANTIGEN DNA HELICASE; 1.
DR PANTHER; PTHR12604:SF2; X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 6; 1.
DR Pfam; PF02735; Ku; 1.
DR Pfam; PF03730; Ku_C; 1.
DR Pfam; PF03731; Ku_N; 1.
DR Pfam; PF02037; SAP; 1.
DR PIRSF; PIRSF003033; Ku70; 1.
DR SMART; SM00559; Ku78; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR SUPFAM; SSF100939; SPOC domain-like; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50800; SAP; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008827}.
FT DOMAIN 598..632
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT REGION 552..574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 634 AA; 71727 MW; B3335AD72765B7DB CRC64;
MDLDGDDNDN DIFRDDEDDP QAQLSLLENE SSKEYVVYLV DASPKMFSTT CPAEEDDQNG
ETHFHIAISC ISQTLESQII NRSYDQVAIC FFNTREKNNL QDLNSVFVFN VPEREFLDRP
TARLIKEFYQ LEESFSKIIG SQHGIVSGTR ENSLYNAIWA AQALLRKGSA KTVDKRILLF
TNDDDPFGSI KGAVKSDMTR MTLQRAKDAQ DLGISIELLP LSHPDEVFNV SQFYADLIGL
EGDDLVDFMP SAGKKLEDMK DQLRKRMFTK RIVKRLKFMI VNGISIELNS YALIRPTVPG
AITWLDSVTN HPLKIERTFI CVDTGALVEE PTKRFLPYKN QNIIFSMKQL SEIKRVSTGH
LHLLGFKPLS CLRDYYNLKP STFLYPSDEG TDSSMCMFIA LHRSMIQLNR FAVAFSGSSS
RPQLVALIAQ EEVIQSGGQI EPPGMHMIYL PYSDDIRFVE ERYSDTSGMV NIASDDQIKK
AANLIKRIDL KDFSVCQISN PALQRHYAVL QALALEEDDI PEMKDESLPD EEGLARPGVV
RALEEFKTSV YGDNYDEENE PGTEKPTEAS KKRKANAEFA TKECENYDWG DLADTGKLKD
LTVVELKYYL TAHNLPVSGK KEAIISRILT HMAK
//
