ID K7PMA6_9CAUD Unreviewed; 478 AA.
AC K7PMA6;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=mEp234_044 {ECO:0000313|EMBL:AFM76323.1};
OS Escherichia phage mEp234.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Hendrixvirinae; Wanchaivirus; Wanchaivirus mEp234.
OX NCBI_TaxID=1147157 {ECO:0000313|EMBL:AFM76323.1, ECO:0000313|Proteomes:UP000010394};
RN [1] {ECO:0000313|Proteomes:UP000010394}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Refardt D., Gencoglu M., Kunzli-Gontarczyk M., Bruggmann R.,
RA Kropinski A.M.;
RT "The genomes of several lambdoid coliphages.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. DnaB subfamily.
CC {ECO:0000256|ARBA:ARBA00008428}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JQ182732; AFM76323.1; -; Genomic_DNA.
DR RefSeq; YP_007112057.1; NC_019715.1.
DR GeneID; 14181944; -.
DR KEGG; vg:14181944; -.
DR OrthoDB; 2382at10239; -.
DR Proteomes; UP000010394; Genome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd00984; DnaB_C; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036185; DNA_heli_DnaB-like_N_sf.
DR InterPro; IPR007694; DNA_helicase_DnaB-like_C.
DR InterPro; IPR007693; DNA_helicase_DnaB-like_N.
DR InterPro; IPR019889; DNA_helicase_DnaB-like_phg.
DR InterPro; IPR016136; DNA_helicase_N/primase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03600; phage_DnaB; 1.
DR PANTHER; PTHR30153:SF2; REPLICATIVE DNA HELICASE; 1.
DR PANTHER; PTHR30153; REPLICATIVE DNA HELICASE DNAB; 1.
DR Pfam; PF00772; DnaB; 1.
DR Pfam; PF03796; DnaB_C; 1.
DR SUPFAM; SSF48024; N-terminal domain of DnaB helicase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51199; SF4_HELICASE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000010394}.
FT DOMAIN 184..459
FT /note="SF4 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51199"
FT REGION 456..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 458..478
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 478 AA; 53467 MW; CAEF8A062FC8CC9A CRC64;
MTDNFYAPPH SIEAEQAVIG GLLLDDDSSE RVQKVLAILK PDSFYSRPHK ILFEEITRMH
REQKPVDGLT LFDELERKSL TASVGGFAYI AEIAKNTPSA ANIVAYAMQV RETAMERYAI
NRMTEATELL YSRNGMTATQ KYEAIQSIFT QLTDHAKTGS RRGLRSFGEV MEDWVSDLEK
RFDPSGEQRG MSTGIPSLDR MLSPKGLVKG SLFVIGARPK MGKTTLYSQM AINCAVHEKK
PALMFSLEMP GDQILEKLVG QKSGVNPNIF YLPATNDADD GYQGDYDGDF NRAIETANRL
SEIDLLYIDD TPGLSLAQIV SESRRIKREK GCVGMILVDY LTLMTAEKAD RNDLAYGMIT
KGLKNLAKEL DCVVVLLTQL NRALESRTNK RPLPCDSRDT GQIEQDCDYW VGIHREGAFD
DSVPPGETEL ILRLNRHGNT GTVYCIQANG AIYDTDQQSA EMRRREREEP QSKKKGGF
//
