ID K7R9G5_9CAUD Unreviewed; 211 AA.
AC K7R9G5;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=dTMP kinase {ECO:0000256|ARBA:ARBA00012980};
DE EC=2.7.4.9 {ECO:0000256|ARBA:ARBA00012980};
GN ORFNames=MAR10_074 {ECO:0000313|EMBL:AFV81308.1};
OS Vibrio phage vB_VpaS_MAR10.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Mardecavirus; Mardecavirus MAR10.
OX NCBI_TaxID=1229755 {ECO:0000313|EMBL:AFV81308.1, ECO:0000313|Proteomes:UP000009398};
RN [1] {ECO:0000313|EMBL:AFV81308.1, ECO:0000313|Proteomes:UP000009398}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23166255; DOI=10.1128/JVI.02666-12;
RA Alanis Villa A., Kropinski A.M., Abbasifar R., Abbasifar A.,
RA Griffiths M.W.;
RT "Genome Sequence of Temperate Vibrio parahaemolyticus Bacteriophage
RT vB_VpaS_MAR10.";
RL J. Virol. 86:13851-13852(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + dTMP = ADP + dTDP; Xref=Rhea:RHEA:13517,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58369, ChEBI:CHEBI:63528,
CC ChEBI:CHEBI:456216; EC=2.7.4.9;
CC Evidence={ECO:0000256|ARBA:ARBA00001008};
CC -!- SIMILARITY: Belongs to the thymidylate kinase family.
CC {ECO:0000256|ARBA:ARBA00009776}.
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DR EMBL; JX556418; AFV81308.1; -; Genomic_DNA.
DR RefSeq; YP_007111922.1; NC_019713.1.
DR GeneID; 14181807; -.
DR KEGG; vg:14181807; -.
DR OrthoDB; 28851at10239; -.
DR UniPathway; UPA00575; -.
DR Proteomes; UP000009398; Genome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004798; F:thymidylate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006233; P:dTDP biosynthetic process; IEA:InterPro.
DR GO; GO:0006235; P:dTTP biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01672; TMPK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00165; Thymidylate_kinase; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039430; Thymidylate_kin-like_dom.
DR InterPro; IPR018094; Thymidylate_kinase.
DR NCBIfam; TIGR00041; DTMP_kinase; 1.
DR PANTHER; PTHR10344; THYMIDYLATE KINASE; 1.
DR PANTHER; PTHR10344:SF4; THYMIDYLATE KINASE; 1.
DR Pfam; PF02223; Thymidylate_kin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000313|EMBL:AFV81308.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000009398};
KW Transferase {ECO:0000313|EMBL:AFV81308.1}.
FT DOMAIN 9..163
FT /note="Thymidylate kinase-like"
FT /evidence="ECO:0000259|Pfam:PF02223"
SQ SEQUENCE 211 AA; 23884 MW; 1D3C026018B70AAA CRC64;
MTRGVIVAIE GFDGSGKSTL TKQLVEELSN YNVRVVQTRQ PGGTPFAEEI RSLLMTGQRD
RSQRVEAHLF LAARHDLYDK LIQPEVEAGS IVVCDRHYIS SLANQPECAE MFLQDRVFDP
DVWIMARCPF PVCITRSEAR GDTDAFSDDD LVEKRAQYDR YQHGLRSAKQ FSATDSIFTI
DTDLGLTSSR EQVKKVASYI VNLNKQRPYN S
//
