ID K7UGV9_MAIZE Unreviewed; 425 AA.
AC K7UGV9;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=E2F transcription factor-like E2FE {ECO:0000313|EMBL:AQK83467.1};
DE SubName: Full=E2F-DP transcription factor {ECO:0000313|EMBL:AIB05518.1};
DE Flags: Fragment;
GN Name=E2F12 {ECO:0000313|EMBL:AIB05518.1};
GN Synonyms=103629955 {ECO:0000313|EnsemblPlants:Zm00001eb280090_P001};
GN ORFNames=ZEAMMB73_Zm00001d037274 {ECO:0000313|EMBL:AQK83467.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:AIB05518.1};
RN [1] {ECO:0000313|EnsemblPlants:Zm00001eb280090_P001, ECO:0000313|Proteomes:UP000007305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb280090_P001,
RC ECO:0000313|Proteomes:UP000007305};
RX PubMed=19965430; DOI=10.1126/science.1178534;
RA Schnable P.S., Ware D., Fulton R.S., Stein J.C., Wei F., Pasternak S.,
RA Liang C., Zhang J., Fulton L., Graves T.A., Minx P., Reily A.D.,
RA Courtney L., Kruchowski S.S., Tomlinson C., Strong C., Delehaunty K.,
RA Fronick C., Courtney B., Rock S.M., Belter E., Du F., Kim K., Abbott R.M.,
RA Cotton M., Levy A., Marchetto P., Ochoa K., Jackson S.M., Gillam B.,
RA Chen W., Yan L., Higginbotham J., Cardenas M., Waligorski J., Applebaum E.,
RA Phelps L., Falcone J., Kanchi K., Thane T., Scimone A., Thane N., Henke J.,
RA Wang T., Ruppert J., Shah N., Rotter K., Hodges J., Ingenthron E.,
RA Cordes M., Kohlberg S., Sgro J., Delgado B., Mead K., Chinwalla A.,
RA Leonard S., Crouse K., Collura K., Kudrna D., Currie J., He R.,
RA Angelova A., Rajasekar S., Mueller T., Lomeli R., Scara G., Ko A.,
RA Delaney K., Wissotski M., Lopez G., Campos D., Braidotti M., Ashley E.,
RA Golser W., Kim H., Lee S., Lin J., Dujmic Z., Kim W., Talag J., Zuccolo A.,
RA Fan C., Sebastian A., Kramer M., Spiegel L., Nascimento L., Zutavern T.,
RA Miller B., Ambroise C., Muller S., Spooner W., Narechania A., Ren L.,
RA Wei S., Kumari S., Faga B., Levy M.J., McMahan L., Van Buren P.,
RA Vaughn M.W., Ying K., Yeh C.-T., Emrich S.J., Jia Y., Kalyanaraman A.,
RA Hsia A.-P., Barbazuk W.B., Baucom R.S., Brutnell T.P., Carpita N.C.,
RA Chaparro C., Chia J.-M., Deragon J.-M., Estill J.C., Fu Y., Jeddeloh J.A.,
RA Han Y., Lee H., Li P., Lisch D.R., Liu S., Liu Z., Nagel D.H., McCann M.C.,
RA SanMiguel P., Myers A.M., Nettleton D., Nguyen J., Penning B.W.,
RA Ponnala L., Schneider K.L., Schwartz D.C., Sharma A., Soderlund C.,
RA Springer N.M., Sun Q., Wang H., Waterman M., Westerman R., Wolfgruber T.K.,
RA Yang L., Yu Y., Zhang L., Zhou S., Zhu Q., Bennetzen J.L., Dawe R.K.,
RA Jiang J., Jiang N., Presting G.G., Wessler S.R., Aluru S.,
RA Martienssen R.A., Clifton S.W., McCombie W.R., Wing R.A., Wilson R.K.;
RT "The B73 maize genome: complexity, diversity, and dynamics.";
RL Science 326:1112-1115(2009).
RN [2] {ECO:0000313|EMBL:AIB05518.1}
RP NUCLEOTIDE SEQUENCE.
RA Burdo B., Gray J., Goetting-Minesky M.P., Wittler B., Hunt M., Li T.,
RA Velliquette D., Thomas J., Gentzel I., Dos Santos Brito M.,
RA Mejia-Guerra M.K., Connolly L.N., Qaisi D., Li W., Casas M.I., Doseff A.I.,
RA Grotewold E.;
RT "The Maize TFome - Development of a transcription factor open reading frame
RT collection for functional genomics.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AQK83467.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Seedling {ECO:0000313|EMBL:AQK83467.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EnsemblPlants:Zm00001eb280090_P001}
RP IDENTIFICATION.
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb280090_P001};
RG EnsemblPlants;
RL Submitted (MAY-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU003796}.
CC -!- SIMILARITY: Belongs to the E2F/DP family.
CC {ECO:0000256|ARBA:ARBA00010940, ECO:0000256|RuleBase:RU003796}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KJ728027; AIB05518.1; -; mRNA.
DR EMBL; CM000782; AQK83467.1; -; Genomic_DNA.
DR EMBL; CM000782; AQK83469.1; -; Genomic_DNA.
DR RefSeq; XP_008649275.1; XM_008651053.1.
DR RefSeq; XP_008649276.1; XM_008651054.1.
DR AlphaFoldDB; K7UGV9; -.
DR SMR; K7UGV9; -.
DR PaxDb; 4577-GRMZM2G060000_P02; -.
DR EnsemblPlants; Zm00001eb280090_T001; Zm00001eb280090_P001; Zm00001eb280090.
DR EnsemblPlants; Zm00001eb280090_T002; Zm00001eb280090_P002; Zm00001eb280090.
DR GeneID; 103629955; -.
DR Gramene; Zm00001eb280090_T001; Zm00001eb280090_P001; Zm00001eb280090.
DR Gramene; Zm00001eb280090_T002; Zm00001eb280090_P002; Zm00001eb280090.
DR KEGG; zma:103629955; -.
DR eggNOG; KOG2578; Eukaryota.
DR OrthoDB; 1761at2759; -.
DR Proteomes; UP000007305; Chromosome 6.
DR ExpressionAtlas; K7UGV9; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR015633; E2F.
DR InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12081:SF75; OS06G0245900 PROTEIN; 1.
DR PANTHER; PTHR12081; TRANSCRIPTION FACTOR E2F; 1.
DR Pfam; PF02319; E2F_TDP; 2.
DR SMART; SM01372; E2F_TDP; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
PE 1: Evidence at protein level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003796};
KW Nucleus {ECO:0000256|RuleBase:RU003796};
KW Proteomics identification {ECO:0007829|PeptideAtlas:K7UGV9};
KW Reference proteome {ECO:0000313|Proteomes:UP000007305};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU003796};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU003796}.
FT DOMAIN 55..120
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT DOMAIN 200..280
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 147..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..169
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 425
FT /evidence="ECO:0000313|EMBL:AIB05518.1"
SQ SEQUENCE 425 AA; 47027 MW; EE201435AC0110AD CRC64;
MDASAATPAP GPSFSGAESS AAAAQPPAEA PQLRVHGAGS GSGVARACRH HAYSRKQKSL
GLLCSNFVAL YDREDVEVIG LDDAAKRLGV ERRRIYDIVN VLESVGILVR RAKNRYTWLG
FGGVPAALKE LKERALRKMS GSPVLLSMED SSTANLSDDE DDEKLGDADE DAESEKLSQP
VDNTSDKPDA PSCRLRSDHR KEKSLGLLTQ NFVKLFLNME VGTISLDEAA RLLLGEGHAD
SNMRTKVRRL YDIANVLSSL NLIEKTQQAD TRKPAFRWLG QAKRKQDNNV MVSVPPSMKA
MPNKRAFGTD LTNIDNKRGK LDSAAENKVK LMQGAGNIVK TFERQLVQGK RSDFVYGPFH
PAGAKKHETD DQTVKQQERK NIQDWENLAV SFRPQYQNQA LNDLFGHYVE AWKSWYVDLT
QETAS
//
