ID K7V321_MAIZE Unreviewed; 704 AA.
AC K7V321;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=ATP-dependent zinc metalloprotease FTSH 4 mitochondrial {ECO:0000313|EMBL:AQK96236.1};
GN ORFNames=ZEAMMB73_Zm00001d011220 {ECO:0000313|EMBL:AQK96236.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EnsemblPlants:Zm00001eb357200_P004, ECO:0000313|Proteomes:UP000007305};
RN [1] {ECO:0000313|EnsemblPlants:Zm00001eb357200_P004, ECO:0000313|Proteomes:UP000007305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb357200_P004,
RC ECO:0000313|Proteomes:UP000007305};
RX PubMed=19965430; DOI=10.1126/science.1178534;
RA Schnable P.S., Ware D., Fulton R.S., Stein J.C., Wei F., Pasternak S.,
RA Liang C., Zhang J., Fulton L., Graves T.A., Minx P., Reily A.D.,
RA Courtney L., Kruchowski S.S., Tomlinson C., Strong C., Delehaunty K.,
RA Fronick C., Courtney B., Rock S.M., Belter E., Du F., Kim K., Abbott R.M.,
RA Cotton M., Levy A., Marchetto P., Ochoa K., Jackson S.M., Gillam B.,
RA Chen W., Yan L., Higginbotham J., Cardenas M., Waligorski J., Applebaum E.,
RA Phelps L., Falcone J., Kanchi K., Thane T., Scimone A., Thane N., Henke J.,
RA Wang T., Ruppert J., Shah N., Rotter K., Hodges J., Ingenthron E.,
RA Cordes M., Kohlberg S., Sgro J., Delgado B., Mead K., Chinwalla A.,
RA Leonard S., Crouse K., Collura K., Kudrna D., Currie J., He R.,
RA Angelova A., Rajasekar S., Mueller T., Lomeli R., Scara G., Ko A.,
RA Delaney K., Wissotski M., Lopez G., Campos D., Braidotti M., Ashley E.,
RA Golser W., Kim H., Lee S., Lin J., Dujmic Z., Kim W., Talag J., Zuccolo A.,
RA Fan C., Sebastian A., Kramer M., Spiegel L., Nascimento L., Zutavern T.,
RA Miller B., Ambroise C., Muller S., Spooner W., Narechania A., Ren L.,
RA Wei S., Kumari S., Faga B., Levy M.J., McMahan L., Van Buren P.,
RA Vaughn M.W., Ying K., Yeh C.-T., Emrich S.J., Jia Y., Kalyanaraman A.,
RA Hsia A.-P., Barbazuk W.B., Baucom R.S., Brutnell T.P., Carpita N.C.,
RA Chaparro C., Chia J.-M., Deragon J.-M., Estill J.C., Fu Y., Jeddeloh J.A.,
RA Han Y., Lee H., Li P., Lisch D.R., Liu S., Liu Z., Nagel D.H., McCann M.C.,
RA SanMiguel P., Myers A.M., Nettleton D., Nguyen J., Penning B.W.,
RA Ponnala L., Schneider K.L., Schwartz D.C., Sharma A., Soderlund C.,
RA Springer N.M., Sun Q., Wang H., Waterman M., Westerman R., Wolfgruber T.K.,
RA Yang L., Yu Y., Zhang L., Zhou S., Zhu Q., Bennetzen J.L., Dawe R.K.,
RA Jiang J., Jiang N., Presting G.G., Wessler S.R., Aluru S.,
RA Martienssen R.A., Clifton S.W., McCombie W.R., Wing R.A., Wilson R.K.;
RT "The B73 maize genome: complexity, diversity, and dynamics.";
RL Science 326:1112-1115(2009).
RN [2] {ECO:0000313|EMBL:AQK96236.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Seedling {ECO:0000313|EMBL:AQK96236.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:Zm00001eb357200_P004}
RP IDENTIFICATION.
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb357200_P004};
RG EnsemblPlants;
RL Submitted (MAY-2021) to UniProtKB.
CC -!- FUNCTION: Probable ATP-dependent zinc metallopeptidase.
CC {ECO:0000256|ARBA:ARBA00003497}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: In the C-terminal section; belongs to the peptidase M41
CC family. {ECO:0000256|ARBA:ARBA00010044}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the AAA ATPase
CC family. {ECO:0000256|ARBA:ARBA00010550}.
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DR EMBL; CM000784; AQK96236.1; -; Genomic_DNA.
DR EMBL; CM000784; AQK96237.1; -; Genomic_DNA.
DR EMBL; CM000784; AQK96239.1; -; Genomic_DNA.
DR RefSeq; XP_008655320.1; XM_008657098.1.
DR AlphaFoldDB; K7V321; -.
DR SMR; K7V321; -.
DR IntAct; K7V321; 2.
DR STRING; 4577.K7V321; -.
DR MEROPS; M41.018; -.
DR MEROPS; M41.026; -.
DR PaxDb; 4577-GRMZM2G096764_P01; -.
DR EnsemblPlants; Zm00001eb357200_T004; Zm00001eb357200_P004; Zm00001eb357200.
DR Gramene; Zm00001eb357200_T004; Zm00001eb357200_P004; Zm00001eb357200.
DR eggNOG; KOG0734; Eukaryota.
DR HOGENOM; CLU_000688_9_3_1; -.
DR InParanoid; K7V321; -.
DR OrthoDB; 9585at2759; -.
DR Proteomes; UP000007305; Chromosome 8.
DR ExpressionAtlas; K7V321; baseline and differential.
DR GO; GO:0009534; C:chloroplast thylakoid; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IBA:GO_Central.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IBA:GO_Central.
DR CDD; cd19501; RecA-like_FtsH; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.58.760; Peptidase M41; 1.
DR HAMAP; MF_01458; FtsH; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR005936; FtsH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000642; Peptidase_M41.
DR InterPro; IPR037219; Peptidase_M41-like.
DR NCBIfam; TIGR01241; FtsH_fam; 1.
DR PANTHER; PTHR23076:SF37; ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1; 1.
DR PANTHER; PTHR23076; METALLOPROTEASE M41 FTSH; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF01434; Peptidase_M41; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF140990; FtsH protease domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 1: Evidence at protein level;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000313|EMBL:AQK96236.1};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:AQK96236.1};
KW Proteomics identification {ECO:0007829|PeptideAtlas:K7V321};
KW Reference proteome {ECO:0000313|Proteomes:UP000007305};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT DOMAIN 255..391
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 658..677
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 704 AA; 76044 MW; 19360CCEAB4BD5D0 CRC64;
MAWRRVLTQI ARHRPTKAIY NELVASSPLG AFQSDITAGA RIKNLQERNQ SSYIGSLARR
VRDLESPSQT SLLKEIYRSD PERVIQIFES HPSLHSNPAA LSEYVKALVR VDRLDESALL
KTLQRGVVSL TRGEESFSSI PALIGAGQLT KDGALGTANA PIHMVTAETG QFKDQLWRTF
RSIALTFLLI SGIGALIEDR GISKGLGLNE EVQPSIESTT KFSDVKGVDE AKSELEEIVH
YLRDPKRFTR LGGKLPKGVL LVGPPGTGKT MLARAIAGEA GVPFFSCSGS EFEEMFVGVG
ARRVRDLFAA AKKRSPCIIF IDEIDAIGGS RNPKDQQYMK MTLNQLLVEL DGFKQNQGII
VIAATNFPES LDKALIRPGR FDRHIVVPNP DVEGRRQILE SHMSKILKGD DVDLMIIARG
TPGFSGADLA NLVNVAALKA AMDGAKSVTM NDLEYAKDRI MMGSERKSAV ISDECRKLTA
YHEGGHALVA IHTEGAHPVH KATIVPRGVA LGMVAQLPDK DQTSVSRKQM LAKLDVCMGG
RVAEELIFGD TEVTSGASSD FQQATAMARA MVTKYGMSKH VGLVSYNYED DGKSVSSETR
LVIEQEVKNF LENAYNNAKT ILTKHNKELH ALANALLEHE TLTGAQITNI LAQVRNKQQQ
EHTVEAPQRA PASPASPAAA AAAAAAAAAQ QAAAKAKGVA GMGS
//
