ID K7VX72_9NOST Unreviewed; 909 AA.
AC K7VX72;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 24-JAN-2024, entry version 56.
DE RecName: Full=FtsK domain-containing protein {ECO:0000259|PROSITE:PS50901};
GN ORFNames=ANA_C10598 {ECO:0000313|EMBL:AFW93397.1};
OS Anabaena sp. 90.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Anabaena.
OX NCBI_TaxID=46234 {ECO:0000313|EMBL:AFW93397.1, ECO:0000313|Proteomes:UP000010101};
RN [1] {ECO:0000313|EMBL:AFW93397.1, ECO:0000313|Proteomes:UP000010101}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=90 {ECO:0000313|EMBL:AFW93397.1};
RX PubMed=23148582; DOI=10.1186/1471-2164-13-613;
RA Wang H., Sivonen K., Rouhiainen L., Fewer D.P., Lyra C., Rantala-Ylinen A.,
RA Vestola J., Jokela J., Rantasarkka K., Li Z., Liu B.;
RT "Genome-derived insights into the biology of the hepatotoxic bloom-forming
RT cyanobacterium Anabaena sp. strain 90.";
RL BMC Genomics 13:613-613(2012).
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
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DR EMBL; CP003284; AFW93397.1; -; Genomic_DNA.
DR RefSeq; WP_015078561.1; NC_019427.1.
DR AlphaFoldDB; K7VX72; -.
DR STRING; 46234.ANA_C10598; -.
DR KEGG; anb:ANA_C10598; -.
DR PATRIC; fig|46234.3.peg.676; -.
DR eggNOG; COG0349; Bacteria.
DR eggNOG; COG1674; Bacteria.
DR HOGENOM; CLU_015451_0_0_3; -.
DR OrthoDB; 9807790at2; -.
DR Proteomes; UP000010101; Chromosome chANA01.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR CDD; cd06142; RNaseD_exo; 1.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000010101}.
FT DOMAIN 678..868
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 518..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 518..534
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 697..704
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 909 AA; 103021 MW; 6528F491F73FBFB3 CRC64;
MHYLTEASEI YKQISQLSLS KTLWIDTEIA DWYTDKPKLA LIQVLANYTD LTGESAYIFD
VLDKPDLAVY FINQIMVNPQ IEKVFHNAGF DLKYLGKELA QNVTCTLKIA RKITKEVLET
TNLKLKTLAA ELCQFSHVDA EEGTSDWGKR PLTQKQLNYA AMDTVYLATV HYRLLEISNP
DVINRVFNMV NHKSENSSLT PTKVRLAFEC PRLFYLNHHF NCKAIFSPKD TLGGVGNVFH
KLADDFINLL LIEPRFKNLF NPSTTQLNVD QITSEIQQLF YQIKFFPYLQ NTIVQDGSKA
PVLLQVWQGL QGLIKKFTEL LVINRRYCSA EKLISNTFIS GERNLEHYFD LPNGTKQLIR
GEFDCLVFNF ELKRLCMVEF KTYQPVDSAA QLAQVSLYSY MLWKQKKAPV DSAVYCVLPE
FKEYKYSWEQ LENTVHQLIP YKLLQMQQWL SWESPNPNPP PATTQPHLCE ICPQQQKCQT
FFDVESNAPP NKVIPDNDNP DFIAPSKKRE DISDFSHYLE NPTRNLTPQP PSLRGKGENS
KPLSLQERGL ERGFSDTFKS QKDTFINADE IGASLVAILE SFKVNVDYYG ADVSPAFIRV
KIKPHLGVKV PSILRLSADL QVQLGLEYPP LIAPQAGYVS IDLPRQDRQI AKFEDFIQKQ
FLAPTAPVKI AIGVGIDGKL LEADLSDPNT CHFLVGGTTG SGKSEFLRSL LLSLIYRHSP
QHLKIALVDP KRVTFPEFEQ MSWLYAPVVK DSDRAVELMQ ELVAEMESRY QKFEKAKCAD
LTTYNQRSSP ALPRIVCIFD EYADFMAEKE IRTILEQSIK RLGAMARAAG IHLIISTQRP
EASIVTPIIR SNLPGRVALR TSSQADSCII LGGKETTAAY LLGKGDLVYQ GGSHGQRLQS
LLAQTIKLP
//
