ID K7WFP5_9NOST Unreviewed; 459 AA.
AC K7WFP5;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Carotenoid oxygenase {ECO:0000313|EMBL:AFW94328.1};
GN ORFNames=ANA_C11554 {ECO:0000313|EMBL:AFW94328.1};
OS Anabaena sp. 90.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Anabaena.
OX NCBI_TaxID=46234 {ECO:0000313|EMBL:AFW94328.1, ECO:0000313|Proteomes:UP000010101};
RN [1] {ECO:0000313|EMBL:AFW94328.1, ECO:0000313|Proteomes:UP000010101}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=90 {ECO:0000313|EMBL:AFW94328.1};
RX PubMed=23148582; DOI=10.1186/1471-2164-13-613;
RA Wang H., Sivonen K., Rouhiainen L., Fewer D.P., Lyra C., Rantala-Ylinen A.,
RA Vestola J., Jokela J., Rantasarkka K., Li Z., Liu B.;
RT "Genome-derived insights into the biology of the hepatotoxic bloom-forming
RT cyanobacterium Anabaena sp. strain 90.";
RL BMC Genomics 13:613-613(2012).
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787}.
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DR EMBL; CP003284; AFW94328.1; -; Genomic_DNA.
DR AlphaFoldDB; K7WFP5; -.
DR STRING; 46234.ANA_C11554; -.
DR KEGG; anb:ANA_C11554; -.
DR PATRIC; fig|46234.3.peg.1740; -.
DR eggNOG; COG3670; Bacteria.
DR HOGENOM; CLU_016472_0_2_3; -.
DR Proteomes; UP000010101; Chromosome chANA01.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR PANTHER; PTHR10543:SF89; CAROTENOID 9,10(9',10')-CLEAVAGE DIOXYGENASE 1; 1.
DR Pfam; PF03055; RPE65; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000010101}.
FT BINDING 166
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 214
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 278
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 454
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ SEQUENCE 459 AA; 51527 MW; F79489A66898FFAC CRC64;
MTIASTAVNP YLAGNFAPIN TEVSTDNLEV IGEIPPELSG MFVRNGPNPQ WSPIGQYHWF
DGDGMLHGVQ INDGKATYHN RYVRTRGWNI EHEAGKAVWS GLLEPPQMDN PHGPGKNTAN
TALVWHNQQL LALWEGGAPH HINTADLATI GEHTYNGKLI SAFTAHPKVD PVTGEMMFFG
YGFRPPYLQY GVVSAQGELL RTVPIEIPTA VMMHDFAITE NYTIFMDLPL TFSAERMMRG
EPMMMFESDR PSRFGIMPRH GDSSNIRWFE CPPCYVFHTL NAYEAGDEVL LIACRMNSTN
VLISQDTHSD PKGDIPFLHR WRFNLSTGVV TEEQLDDVPG EFPRVNEKLL GRKTQYGYVG
KMANNPNPLF DGLIKYDFEN GKSQTHEFGK NRYGGEAVFA PDPNSTVEDK GWLVTFIYDE
NSQTSELVVI NAQDITSEPI ARVMIPQRVP YGFHGIWIS
//
